Gene Information

Name : fliP (CA_C2150)
Accession : NP_348768.1
Strain : Clostridium acetobutylicum ATCC 824
Genome accession: NC_003030
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 2242728 - 2243513 bp
Length : 786 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence :

ATGAAAAAGAAAAGTTTTATCATGCTTGCTGTATTTTTGGTATTCCTTGCTTTTCTTGGAGCTAGGGCTCATGCAGCACC
AGTTGATACTGCAAGTACAATACAGATACCTAAAGTCAATATTTCAGTTGACAATGCGAATTCTAACAATCCTAAGGATT
TTGTAGATAATATAAAACTTCTTTTAGTACTTACTGTTATTACTTTACTTCCTTCAATAATAATGATGATGACAAGTTTT
ACAAGAATAATAGTAGTATTGGGATTTTTAAGAACTTCTATGGGAACACAGCAGTCACCACCTAATCAGGTACTTATAGG
CTTGGCTTTATTTTTAACTATGTTTATTATGATGCCAACATATAAACAAATAAATAAAAATGCAATTCAGCCTTATTTAA
ACAAGTCAATAAGTCAGCAGCAGGCTCTTTTAGAAATGGAAAAGCCTCTTAGAACATTTATGTACAAGCAAACCTATCAA
AAGGATTTGAAATTATTTATTGATTTAGATAATCAGTCAGGGAAAATTACAAAGGACACAGTTCCTTTTCACGATATAGT
TCCAGCGTTTATTATAAGTGAACTTAAGACTGCATTTACAATAGGATTTTTATTATATATACCATTTCTTATAATAGATT
TGGTTGTTGCAAGTATTCTTATGTCAATGGGTATGATGATGCTTCCACCAGTTATGGTCTCTATGCCATTTAAACTTCTT
TTGTTTATAATGGTAGATGGATGGTATCTTATAGTTAAATCTCTTGTCTTAAGTTTTGGAGGGTGA

Protein sequence :

MKKKSFIMLAVFLVFLAFLGARAHAAPVDTASTIQIPKVNISVDNANSNNPKDFVDNIKLLLVLTVITLLPSIIMMMTSF
TRIIVVLGFLRTSMGTQQSPPNQVLIGLALFLTMFIMMPTYKQINKNAIQPYLNKSISQQQALLEMEKPLRTFMYKQTYQ
KDLKLFIDLDNQSGKITKDTVPFHDIVPAFIISELKTAFTIGFLLYIPFLIIDLVVASILMSMGMMMLPPVMVSMPFKLL
LFIMVDGWYLIVKSLVLSFGG

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
XC_3016	YP_244084.1	type III secretion system protein	Virulence	Hrp PAI	Protein	5e-26	45
hrcR	NP_636600.1	type III secretion system protein	Virulence	Hrp PAI	Protein	5e-26	45
hrcR	BAB07862.1	HrcR	Virulence	Hrp PAI	Protein	9e-26	44
hrcR	AAP34349.1	HrcR	Virulence	Hrp PAI	Protein	5e-26	44
hrcR	AAD21321.1	HrcR	Virulence	Hrp PAI	Protein	6e-26	44
hrcR	NP_640757.1	type III secretion system protein	Virulence	Hrp PAI	Protein	8e-26	44
hrcR	YP_362153.1	type III secretion system protein	Virulence	Hrp PAI	Protein	8e-26	44
hrcR	YP_198720.1	type III secretion system protein	Virulence	Hrp PAI	Protein	7e-26	44
escR	AAC31528.1	L0049	Virulence	LEE	Protein	8e-22	43
escR	ACU09473.1	type III secretion system protein EscR	Virulence	LEE	Protein	8e-22	43
escR	YP_003236103.1	T3SS structure protein EscR	Virulence	LEE	Protein	1e-21	43
escR	NP_290283.1	type III secretion system protein	Virulence	LEE	Protein	1e-21	43
escR	AFO66317.1	putative LEE-encoded type III secretion system factor	Virulence	SESS LEE	Protein	6e-24	42
escR	YP_003223490.1	T3SS structure protein EscR	Virulence	LEE	Protein	1e-21	42
escR	AFO66400.1	putative LEE-encoded type III secretion system factor	Virulence	SESS LEE	Protein	6e-24	42
escR	AAC38369.1	EscR	Virulence	LEE	Protein	5e-21	42
escR	YP_003232138.1	type III secretion system protein	Virulence	LEE	Protein	1e-21	42
escR	AAK26700.1	EscR	Virulence	LEE	Protein	1e-21	42
escR	AAL57527.1	EscR	Virulence	LEE	Protein	1e-21	42
escR	CAC81847.1	EscR protein	Virulence	LEE II	Protein	1e-21	42
escR	CAI43889.1	EscR protein	Virulence	LEE	Protein	1e-21	42

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fliP	NP_348768.1	flagellar biosynthesis protein FliP	VFG2338	Protein	2e-39	53
fliP	NP_348768.1	flagellar biosynthesis protein FliP	VFG2494	Protein	2e-39	52
fliP	NP_348768.1	flagellar biosynthesis protein FliP	VFG2016	Protein	6e-42	51
fliP	NP_348768.1	flagellar biosynthesis protein FliP	VFG1259	Protein	8e-47	51
fliP	NP_348768.1	flagellar biosynthesis protein FliP	VFG0827	Protein	5e-22	43
fliP	NP_348768.1	flagellar biosynthesis protein FliP	VFG0715	Protein	3e-21	42