Gene Information

Name : polA (CA_C1098)
Accession : NP_347732.1
Strain : Clostridium acetobutylicum ATCC 824
Genome accession: NC_003030
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 1266368 - 1268983 bp
Length : 2616 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAAGACTGCTTGTGTTAGATGGTAATAGTCTTATGAATAGGGCTTTTTATGCTTTGCCTGAACTTACAAATGCTGA
AGGACTCCATACAAATGGAATATATGGCTTTATGACTATGCTTATAAAAATGCGAGATGAAATAAAGCCTGATTACATAG
TTACAACCTTTGATAGGAAAGCACCTACCTTTAGACATAAGGAATACGAGGATTACAAGGCAGGAAGAAAAAAAATGCCT
CCTGAACTTAGTGAGCAGTTTCCTGTATTAAAAGAATTACTTGAAAAGTTAGCTATAAACATATTTGAAATAGATGGTTT
TGAGGCCGATGACCTCATAGGAACATTAGCATGTTTTGCTAAAGAAAAGGGAATAGAAGTATACATAGTTACAGGGGATA
AAGATGCCCTTCAGCTTGCAGATGATAATGTTAAGGTTGTTATAAATAAAAAAGGAATGACCGAAAAAGAAATATACGAT
AAAAATAGAATGATTGAAGAGTTTGGTGTTACTCCAGTTCAGTTTATAGATGTAAAAGGACTTATGGGAGATAATTCTGA
CAACATACCGGGAGTACCAGGAATAGGCCCTAAGACAGCCTTTAAGCTCATACAAGAATACGGCAGTGTAGAGAATGTTC
TCGACAATATACAAAATATAAAAGGCAAAAAAATAAAAGAGAACTTAGAGAATTATGCAGAGCAAGCAGTTTTTAGTAAA
AAGCTTGCAACCATAATGACTAATGTTCCTATTGAAATAGATATTGAGGAAATAAGATCTAAAGAAAGTTTTGATGTTGA
GGGTGCTAGACATCTTTTAAGAAGACTTCAATTTAAGAGTATAATAGAAAAAATTCCAAGTCTTAATGTTGAAGCGGAAA
AAAGTGATTTTGTTGTAGAGTATAATTTAATAGACGAATTTCCAAAATTTCATGAATTATTTTCAGCTATTAAAGATACT
GAAATTTATATGTCATATTCTATAGGAAATGGAGAGCTGTATTCTAAGATTTATATTGATACAATTTTTATGAAAGTAGA
AGAAAAGACATATATAGTAGATTTAAAGAAAATAATTGAGCAAAATAGAGAAGATGTTCTCAAAGATTTAAAAGAGTTCT
TTGAGAATAAGAAAATAGCTAAGATAATACATGATTCTAAAAATATGTATACAGTGCTTATGAAGAATGGCATAAAAATA
GAGAATCTGGCATTTGATACGGCAATAGCAGAATACCTTATAAATCCATCTAAAAAAGAGTACAATTTAAAAGACGCGGC
GGAAGAGATGCTCTTATTGGATTTGACGGGAGAAGACAATGATATTAAAATAAAAGAAGTTTACGTTATGGATAAAATTT
ACAATAAACTTAAAGACAAAATAAAAGAATATGATATGGATGAGTTATACTATAAAGTAGAGCTTCCACTCATAGAAGTT
TTATCCTCTATGGAGAGTGAAGGATTTAAGGTTGAAAAAAATAAACTTCAACAAATTGGCGATAAATTTACAGTTGAAAT
AGCAAAGGTTAAAGATGAAATATATAACATGGCAGGTGAGGAGTTTAATATAAGTTCTCCAAAGCAACTTGGAAAAATAT
TATTTGAAAAATTGGATTTACCAGTTATAAAGAAAACCAAAACGGGTTACTCCACTAATGCTGAGGTTTTGGAAAAGCTG
ATGGATAAGCATCCTATAATTGAAAAGGTTGTATACTATAGACAGCTTACAAAACTCTATTCAACATATGTTGAAGGACT
TAAACCTGTTATAGATGTTGATGAAAAGATACATTCAAGTTTTAATCAAACTGTAACTACAACAGGTAGGCTTTCAAGTA
CAGAACCAAATCTTCAAAACATACCTATTAAAAATGAGATGGGAAGAGAAATAAGGAAAGTTTTTGTGCCTGAAAATGAT
AATTGTATAATACTTTCAGCAGACTATTCCCAAATAGAATTAAGAGTTTTAGCTCATATTGCTGATGATGAAAATTTAAT
TAATGCATTTAAACATCACAGTGATATCCATACAAAGACAGCTTCGGAGGTTTTTAGAGTACCTATTGAAGAGGTTACGT
CTAGAATGAGAAGTAATGCAAAGGCTGTAAACTTTGGAATTGTCTATGGAATAAGTGATTTCAGTCTAGCTCAGGATATA
AAGGTATCCAAGAAGGAAGCTAAAGAATACATTGATACTTATTTTGAAAGATATCCAAATGTAAAAAAATACTTGGAGGA
TATAGTGGTTACAGCTAAAAAGAATATGTATGTAAACACTATAATGAACAGAAGAAGAATTATTCCAGAAATAGCCTCAT
CAAATAAAATTGTTAAAGGCTTTGGAGAGAGACTTGCTATGAATACACCTATACAGGGAAGTGCAGCAGATCTTATAAAA
CTTTCAATGGTTAATGTGTATAGTAAAATAAAGCAACTAAAGCTTAAAAGTAGGCTTATACTTCAAGTGCATGATGAACT
AATTTTGAATGTACATAAGGATGAACTCGAAAAAGTAAAGGAATTAGTAAAACTTGAAATGGAAGAGGTTATGGAACTTA
AAGTTCCTTTGGAAGTAGATATAGAATCAGGAAATACCTGGTATGAAGCAAAATAA

Protein sequence :
MERLLVLDGNSLMNRAFYALPELTNAEGLHTNGIYGFMTMLIKMRDEIKPDYIVTTFDRKAPTFRHKEYEDYKAGRKKMP
PELSEQFPVLKELLEKLAINIFEIDGFEADDLIGTLACFAKEKGIEVYIVTGDKDALQLADDNVKVVINKKGMTEKEIYD
KNRMIEEFGVTPVQFIDVKGLMGDNSDNIPGVPGIGPKTAFKLIQEYGSVENVLDNIQNIKGKKIKENLENYAEQAVFSK
KLATIMTNVPIEIDIEEIRSKESFDVEGARHLLRRLQFKSIIEKIPSLNVEAEKSDFVVEYNLIDEFPKFHELFSAIKDT
EIYMSYSIGNGELYSKIYIDTIFMKVEEKTYIVDLKKIIEQNREDVLKDLKEFFENKKIAKIIHDSKNMYTVLMKNGIKI
ENLAFDTAIAEYLINPSKKEYNLKDAAEEMLLLDLTGEDNDIKIKEVYVMDKIYNKLKDKIKEYDMDELYYKVELPLIEV
LSSMESEGFKVEKNKLQQIGDKFTVEIAKVKDEIYNMAGEEFNISSPKQLGKILFEKLDLPVIKKTKTGYSTNAEVLEKL
MDKHPIIEKVVYYRQLTKLYSTYVEGLKPVIDVDEKIHSSFNQTVTTTGRLSSTEPNLQNIPIKNEMGREIRKVFVPEND
NCIILSADYSQIELRVLAHIADDENLINAFKHHSDIHTKTASEVFRVPIEEVTSRMRSNAKAVNFGIVYGISDFSLAQDI
KVSKKEAKEYIDTYFERYPNVKKYLEDIVVTAKKNMYVNTIMNRRRIIPEIASSNKIVKGFGERLAMNTPIQGSAADLIK
LSMVNVYSKIKQLKLKSRLILQVHDELILNVHKDELEKVKELVKLEMEEVMELKVPLEVDIESGNTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 7e-150 43