Gene Information

Name : hemC (CA_C0097)
Accession : NP_346742.1
Strain : Clostridium acetobutylicum ATCC 824
Genome accession: NC_003030
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 105680 - 106555 bp
Length : 876 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAGCTTACAATAGCAACTAGAAAGAGCAAGCTTGCTCAGGTGCAGACAGAACTAATAATTAATGTATTAAAAGATAA
ATATGGCATTTCCTCTGAAAAGCTACTGATGGAAACACTTGGAGATAAAATCCTAGATAAGTCACTAGCGGACATAGGGG
GAAAAGGACTTTTTATAAAGGATATAGAAAGAATTCTCTTAGAGGATAAAGCGGATGCAGCAGTTCATAGTATGAAGGAT
GTTCCTTTTGAGGTTCCAGATATGTTTGAAATAGCGGCAGTCACCTTAAGGGTTGATGTAAGGGATGTCTTTGTATCTAG
AGACGGGACTCATTTTAAGGACTTAAAAAATGGAGCGGTTATTGGAACTAGTAGTAACAGAAGAGCAGCTCAGCTTAAAA
TGTTAAGAGATGATATAAAGGTTGTACCCATAAGAGGAAATGTTCAAACCAGAATAAGAAAAATGGGAGAAGAAAAGCTT
GATGGAATAATACTTGCAGCGGCAGGACTTAAGAGACTTAATATGGAGAATATAATTACAGATTATTTTTCTGTAGAGGA
AATGATTCCAGCTGTTGGACAGGGAGCTCTTGGAGTAGAGATAAAGAAGGAAAACAAGAATAGAGATTTATTTAGAAAGT
TAGATAATAAGAATAGCAGAATGTGTGTTGAAGCAGAAAGAAGCTTCATGAGAACTTTAAATGGGGACTGCCATTCTACA
ATTGGAGCTTATGCTGAAATAGTTAATGGGCAAATGAATGTATTGGGATTTTACGAAATTGATGGAAGAAGGGTAAAAAA
AGATGTGAGTGGGAATATAGAGGACTATATGAGTTTAGGGAAAACACTTGCAGAAAAAATTTTGGAGGATAAGTAA

Protein sequence :
MKLTIATRKSKLAQVQTELIINVLKDKYGISSEKLLMETLGDKILDKSLADIGGKGLFIKDIERILLEDKADAAVHSMKD
VPFEVPDMFEIAAVTLRVDVRDVFVSRDGTHFKDLKNGAVIGTSSNRRAAQLKMLRDDIKVVPIRGNVQTRIRKMGEEKL
DGIILAAAGLKRLNMENIITDYFSVEEMIPAVGQGALGVEIKKENKNRDLFRKLDNKNSRMCVEAERSFMRTLNGDCHST
IGAYAEIVNGQMNVLGFYEIDGRRVKKDVSGNIEDYMSLGKTLAEKILEDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-40 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-40 41