|
Name : lysS (SP_0713) Accession : NP_345214.3 Strain : Streptococcus pneumoniae TIGR4 Genome accession: NC_003028 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 676624 - 678099 bp Length : 1476 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGGAAGAACTAAATGACCAGCAGATCGTTCGCCGTGAAAAAATGGCTGCGCTCCGCGAACAAGGAATCGATCCTTTCGG AAAACGTTTTGAACGTACTGCAAATTCACAAGAATTAAAAGATAAATATGCCAACCTCGATAAAGAACAATTACACGATA AAAACGAAACAGCTACTATCGCAGGACGCTTGATAACCAAACGTGGTAAAGGAAAAGTTGGTTTTGCCCACCTTCAAGAC CGCGAAGGCCAGATTCAGATCTACGTTCGTAAGGATGCTGTCGGTGAAGAAAACTACGAAATCTTCAAAAAAGCAGACCT TGGTGACTTCCTTGGTGTCGAAGGTGAAGTGATGCGTACGGATATGGGAGAACTCTCTATCAAGGCAACCCACATCACAC ACTTGTCTAAGGCTCTTCGTCCTCTTCCTGAGAAATTCCATGGTTTGACAGACGTTGAAACAATTTACCGTAAACGTTAC CTTGACTTGATTTCTAATCGTGAAAGCTTTGAACGCTTTGTCACTCGTTCAAAAATCATCTCTGAAATCCGTCGTTACCT TGACCAAAAAGGATTCCTTGAAGTGGAAACACCTGTTCTTCATAATGAAGCCGGTGGTGCTGCTGCCCGTCCATTTATCA CCCACCACAATGCCCAAAACATTGACATGGTGCTTCGTATCGCGACTGAGCTTCACTTAAAACGCCTTATCGTGGGTGGT ATGGAACGTGTCTATGAAATTGGCCGTATCTTCCGTAACGAAGGAATGGACGCTACTCATAACCCTGAGTTCACTTCTAT CGAAGTTTACCAAGCTTATGCAGACTTCCAAGACATCATGGACTTGACTGAAGGCATTATCCAACACGCTGCTAAATCAG TCAAAGGTGATGGCCCAGTCAACTACCAAGGTACTGAAATCAAGATTAACGAACCATTTAAGCGTGTTCATATGGTGGAT GCTATCAGAGAAATTACTGGTGTCGATTTCTGGCAAGACATGACTTTGGAAGAAGCTAAAGCTATCGCTGCTGAGAAGAA AGTTCCAGTTGAGAAACACTACACTGAGGTTGGTCACATCATCAATGCCTTCTTTGAAGAGTTTGTTGAAGAAACTTTAA TCCAACCAACCTTTGTCTATGGACATCCAGTAGCTGTATCTCCACTCGCTAAGAAAAATCCTGAAGACCAACGCTTTACT GACCGTTTCGAGCTCTTTATCATGACTAAGGAGTACGGTAATGCCTTTACTGAGTTGAACGACCCAATCGACCAACTTAG CCGTTTTGAAGCCCAAGCTAAAGCCAAAGAACTTGGTGATGATGAAGCGACAGGAATCGACTATGACTACATTGAAGCTC TTGAATACGGTATGCCACCAACAGGTGGTTTGGGAATCGGTATCGACCGTCTCTGCATGCTCCTCACTGATACAACAACT ATCCGTGATGTATTGCTCTTCCCAACAATGAAATAA Protein sequence : MEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQELKDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQD REGQIQIYVRKDAVGEENYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETIYRKRY LDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFITHHNAQNIDMVLRIATELHLKRLIVGG MERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVD AIREITGVDFWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVSPLAKKNPEDQRFT DRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATGIDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTT IRDVLLFPTMK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 3e-107 | 46 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | NP_345214.3 | lysyl-tRNA synthetase | VFG1668 | Protein | 2e-107 | 46 |
