Gene Information

Name : SP_0350 (SP_0350)
Accession : NP_344883.1
Strain : Streptococcus pneumoniae TIGR4
Genome accession: NC_003028
Putative virulence/resistance : Virulence
Product : capsular polysaccharide biosynthesis protein Cps4E
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2148
EC number : -
Position : 323990 - 324625 bp
Length : 636 bp
Strand : +
Note : identified by match to PFAM protein family HMM PF02397

DNA sequence : 
ATGAAAAATGGAAATAGAATTTATAGTTGGAGGTTGTTTATGTACGGTATAATAAAACGATTAGGTGATATATTATTATC
TTTAATAGGGATAATAATATTGTGTCCGGTTTTTATGATAATTGCAATTGCGATTAAACTTGATTCAGAAGGTCCGGTTA
TATTTAAGCAAAAACGCTTTGGTATTCATAAAGAATACTTCTATATTTTGAAATTTAGGTCTATGAAAATAGATGCACCT
AAAAATGTGGCGCCTCGAAACTTATATAATCCAGAGCAATGGATTACAAAAGTAGGGGCTTTCTTGCGAAAAACATCTTT
GGATGAACTACCACAATTGTTTAATATTCTTGTTGGTAATATGAGTATTGTAGGTCCTAGACCAGCGGGTATAAATGAAC
TAGATTTGATTGCAGAGAGAGATAAGTATGGAGCAAATGATATCTTGCCAGGGTTAACTGGATGGGCACAAATTAACGGG
CGTGATACTTTGTCTGTTGAGATGAAGACGGAGTTAGATGGCTACTATGTTAAACATCTGTCTTTGATAATGGATATTAG
ATGTATAGTTAAGACAATACCTTACGTACTGAAACGAAAAGGTATTGTAGAGGGTAGTGGTAAGAAAGAAAGTTAA

Protein sequence : 
MKNGNRIYSWRLFMYGIIKRLGDILLSLIGIIILCPVFMIIAIAIKLDSEGPVIFKQKRFGIHKEYFYILKFRSMKIDAP
KNVAPRNLYNPEQWITKVGAFLRKTSLDELPQLFNILVGNMSIVGPRPAGINELDLIAERDKYGANDILPGLTGWAQING
RDTLSVEMKTELDGYYVKHLSLIMDIRCIVKTIPYVLKRKGIVEGSGKKES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0070 YP_300160.1 capsular polysaccharide synthesis protein Not tested SCC15305cap Protein 2e-32 49
cap1N AAL26667.1 type 8 capsule synthesis gene Virulence SCCcap1 Protein 4e-30 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SP_0350 NP_344883.1 capsular polysaccharide biosynthesis protein Cps4E VFG1369 Protein 2e-89 100
SP_0350 NP_344883.1 capsular polysaccharide biosynthesis protein Cps4E VFG1309 Protein 3e-32 49