Gene Information

Name : SP_2016 (SP_2016)
Accession : NP_346443.1
Strain : Streptococcus pneumoniae TIGR4
Genome accession: NC_003028
Putative virulence/resistance : Unknown
Product : nicotinate-nucleotide pyrophosphorylase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0157
EC number : 2.4.2.19
Position : 1922125 - 1922997 bp
Length : 873 bp
Strand : -
Note : catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide

DNA sequence :
ATGTCAATCATTTCAACTGATTTAACCCCTTTTCAAATAGATGATACATTGAAAGCAGCCTTGCGAGAAGATGTTCATTC
CGAAGATTACAGTACCAATGCCATTTTTGATCATCATGGCCAAGCCAAGGTGTCGCTTTTTGCCAAGGAAGCTGGTGTTT
TAGCGGGGCTAACCGTTTTTCAAAGGGTTTTTACCCTATTTGATGCCGAGGTGACCTTCCAGAATCCTCATCAATTTAAG
GATGGGGATCGTTTGACTAGTGGCGATTTGGTTTTAGAAATCATAGGCTCGGTGAGAAGTCTCTTAACATGTGAACGCGT
TGCCTTGAATTTTTTACAACATTTATCAGGGATTGCTTCGATGACAGCTGCTTATGTAGAAGCCTTAGGCGATGATTGCA
TTAAGGTATTTGATACTCGAAAAACTACTCCTAATTTACGTCTTTTTGAGAAATATGCCGTGAGAGTTGGCGGTGGCTAT
AATCATCGCTTTAATTTATCAGATGCTATCCTGCTAAAAGACAATCACATTGCGGCAGTAGGTAGTGTTCAAAAGGCAAT
TGCTCAAGCGCGTGCCTATGCCCCTTTTGTGAAAATGGTCGAGGTGGAAGTGGAAAGCCTTGCTGCTGCCGAAGAAGCTG
CGGCGGCGGGTGCTGATATTATCATGTTGGATAATATGTCATTGGAACAGATTGAACAGGCCATTACCCTAATTGCAGGA
CGTTCTCGGATTGAATGTTCTGGAAATATTGATATGACCACTATTAGCCGTTTTCGTGGTTTAGCGATTGATTACGTCTC
CAGTGGTAGTTTAACCCATAGTGCTAAGAGTCTTGATTTTTCCATGAAGGGGTTAACCTACCTTGATGTCTAA

Protein sequence :
MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFK
DGDRLTSGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGADIIMLDNMSLEQIEQAITLIAG
RSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMKGLTYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadC YP_281534.1 nicotinate-nucleotide pyrophosphorylase Not tested Not named Protein 6e-121 99