Gene Information

Name : SP_1994 (SP_1994)
Accession : NP_346421.1
Strain : Streptococcus pneumoniae TIGR4
Genome accession: NC_003028
Putative virulence/resistance : Unknown
Product : aminotransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 1896929 - 1898143 bp
Length : 1215 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGAAAGAATATAACAAGTCTAGTAAGTTAGAGCATGTTGCTTATGATATCCGTGGTCCTGTATTGGAAGAAGCCATGCG
GATGCGAGCGAATGGAGAAAAGATTTTACGTCTGAATACAGGAAATCCAGCAGAATTTGGCTTTACAGCGCCAGACGAGG
TCATTCATGACTTGATTATGAATGCGCGTGATAGTGAAGGCTATTCTGACTCCAAAGGGATTTTCTCAGCCCGTAAGGCC
ATCATGCAGTATTGCCAGCTGAAGAAATTCCCAAACGTAGATACTGATGATATTTACCTTGGAAATGGTGTCAGTGAGTT
GATTGTCATGTCCATGCAGGGGCTTTTGGACAATGGGGATGAGGTCTTAGTGCCAATGCCAGACTATCCTCTATGGACGG
CGGCTGTCAGCCTAGCTGGAGGAAATGCCGTTCACTATATCTGTGATGAAGCTGTGGAATGGTACCCAGATATTGACGAT
ATCAAGTCAAAAATCACTTCCAATACCAAGGCAATTGTCCTTATCAATCCAAATAACCCAACTGGAGCCCTTTATCCTAA
GGAACTCTTGCTGGAGATTATTGAGATTGCCCGTCAAAACGATTTGATTATCTTTGCGGATGAAATCTATGACCGCATGG
TAATGGACGGACATGTGCATACGCCTGTGGCGAGCTTGGCACCAGATGTCTTCTGTGTCAGCATGAATGGTCTGTCAAAA
TCCCACCGCATAGCAGGTTTCCGTGTGGGTTGGATGGTCTTGTCTGGCCCTAAGACTCATGTTAAGGGCTATATCGAAGG
GCTCAATATGCTGTCCAATATGCGCCTTTGCTCTAACGTTTTGGCCCAACAAGTCGTACAAACTTCCTTGGGGGGTCACC
AATCAGTCGATGAATTGCTTCTTCCTGGTGGACGAATCTACGAGCAAAGAAATTTCATCTATAATGCCATTCAAGATATT
CCAGGTTTGTCTGCCGTTAAACCCAAGGCGGGGCTCTATATCTTCCCAAAAATCGACCGCAATATGTACCGTATCGATGA
TGATGAGCAGTTTGTCCTTGATTTCTTGAAGCAGGAAAAGGTTCTCTTGGTTCATGGTCGAGGCTTTAACTGGCAGGAAC
CAGACCACTTCCGTATCGTTTACCTTCCTCGTGTTGATGAGTTAGCCCAAATCCAAGAAAAGATGACTCGTTTCTTGAAA
CAGTATCGTAGATAG

Protein sequence :
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKA
IMQYCQLKKFPNVDTDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-119 57
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-119 57
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-119 57
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-119 57