Gene Information

Name : azi; div (SP_1759)
Accession : NP_346194.1
Strain : Streptococcus pneumoniae TIGR4
Genome accession: NC_003028
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1659641 - 1662013 bp
Length : 2373 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
GTGTTTAGACGTTTAGGTCAAGATTTCCAGCTTAGGAAAGTGAAAAAGATTTTAAAGCAGATTAATGCCCTGAAAGGCAA
GATGTCCTCTCTTTCGGATCAAGAATTAGTAGCTAAAACAGTAGAGTTTCGTCAGCGTCTTTCCGAGGGAGAAAGTCTAG
ACGATATTTTGGTTGAAGCTTTTGCTGTGGTGCGTGAAGCAGATAAGCGGATTTTAGGGATGTTTCCTTATGATGTTCAA
GTCATGGGAGCTATTGTCATGCACTATGGAAATGTTGCTGAGATGAATACGGGGGAAGGTAAGACCTTGACAGCTACCAT
GCCTGTCTATTTGAACGCTTTTTCAGGAGAAGGAGTGATGGTTGTGACTCCTAATGAGTATTTATCAAAGCGTGATGCCG
AGGAAATGGGTCAAGTTTATCGTTTTCTAGGATTGACCATTGGTGTACCATTTACGGAAGATCCAAAGAAGGAGATGAAA
GCTGAAGAAAAGAAGCTTATCTATGCTTCGGATATCATCTACACAACCAATAGTAATTTAGGTTTTGATTATCTAAATGA
TAACCTAGCCTCGAATGAAGAAGGTAAGTTTTTACGACCGTTTAACTATGTGATTATTGATGAAATTGATGATATCTTGC
TTGATAGTGCACAAACTCCTCTGATTATTGCGGGTTCTCCTCGTGTTCAGTCTAATTACTATGCGATCATTGATACACTT
GTAACAACCTTGGTCGAAGGAGAGGATTATATCTTTAAAGAGGAGAAAGAGGAGGTTTGGCTCACTACTAAGGGGGCCAA
GTCTGCTGAGAATTTCCTAGGGATTGATAATTTATACAAGGAAGAGCATGCGTCTTTTGCTCGTCATTTGGTTTATGCGA
TTCGAGCTCATAAGCTCTTTACTAAAGATAAGGACTATATCATTCGTGGAAATGAGATGGTACTGGTTGATAAGGGAACA
GGGCGTCTAATGGAAATGACTAAACTTCAAGGAGGTCTCCATCAGGCTATTGAAGCCAAGGAACATGTCAAATTATCTCC
TGAGACGCGGGCTATGGCCTCGATCACCTATCAGAGTCTTTTTAAGATGTTTAATAAGATATCTGGTATGACAGGGACAG
GTAAGGTCGCGGAAAAAGAGTTTATTGAAACTTACAATATGTCTGTAGTACGCATTCCAACCAATCGTCCGAGACAACGG
ATTGACTATCCAGATAATCTATATATCACTTTACCTGAAAAAGTGTATGCATCCTTGGAGTACATCAAGCAATACCATGC
TAAGGGAAATCCTTTACTCGTTTTTGTAGGCTCAGTTGAAATGTCTCAACTCTATTCGTCTCTCTTGTTTCGTGAAGGGA
TTGCCCATAATGTCCTAAATGCTAATAATGCGGCGCGTGAGGCTCAGATTATCTCCGAGTCAGGTCAGATGGGGGCTGTG
ACAGTGGCTACCTCTATGGCAGGACGTGGTACGGATATCAAGCTTGGTAAAGGAGTCGCAGAGCTTGGGGGCTTGATTGT
TATTGGGACTGAGCGGATGGAAAGTCAGCGGATCGACCTACAAATTCGTGGCCGTTCTGGTCGTCAGGGAGATCCTGGTA
TGAGTAAATTTTTTGTATCCTTAGAGGATGATGTTATCAAGAAATTTGGTCCATCTTGGGTGCATAAAAAGTACAAAGAC
TATCAGGTTCAAGATATGACTCAACCGGAAGTATTGAAAGGTCGTAAATACCGGAAACTAGTCGAAAAGGCTCAGCATGC
CAGTGATAGTGCTGGACGTTCAGCACGTCGTCAGACTCTGGAGTATGCTGAAAGTATGAATATACAACGGGATATAGTCT
ATAAAGAGAGAAATCGTCTAATAGATGGTTCTCGTGACTTAGAGGATGTTGTTGTGGATATCATTGAGAGATATACAGAA
GAGGTAGCGGCTGATCACTATGCTAGTCGTGAATTATTGTTTCACTTTATTGTGACCAATATTAGTTTTCATGTTAAAGA
GGTTCCAGATTATATAGATGTAACTGACAAAACTGCAGTTCGTAGCTTTATGAAGCAGGTGATTGATAAAGAACTTTCTG
AAAAGAAAGAATTACTTAATCAACATGACTTATATGAACAGTTTTTACGACTTTCACTGCTTAAAGCCATTGATGACAAC
TGGGTAGAGCAGGTAGACTATCTACAACAGCTATCCATGGCTATCGGTGGTCAATCTGCTAGTCAGAAAAATCCAATCGT
AGAGTACTATCAAGAAGCCTACGCGGGCTTTGAAGCTATGAAAGAACAGATTCATGCGGATATGGTGCGTAATCTCCTGA
TGGGGCTGGTTGAGGTCACTCCAAAAGGTGAAATCGTGACTCATTTTCCATAA

Protein sequence :
MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQ
VMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTL
VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGT
GRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQR
IDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV
TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKD
YQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTE
EVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN
WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIHADMVRNLLMGLVEVTPKGEIVTHFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 0.0 50