Gene Information

Name : nadE (SP_1420)
Accession : NP_345877.1
Strain : Streptococcus pneumoniae TIGR4
Genome accession: NC_003028
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1340809 - 1341633 bp
Length : 825 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGAGTTTGCAAGAAACGATTATCCAAGAGCTGGGTGTCAAACCAGTGATTGATGCCCAGGAAGAAATCCGTCGTTCTAT
TGATTTCTTAAAAAGATATCTGAAAAAACATCCCTTCCTAAAAACCTTTGTACTAGGGATTTCTGGGGGACAAGACTCAA
CCTTGGCAGGACGTTTGGCGCAATTAGCTATGGAAGAACTGCGAGCTGAAACGGGAGACGATAGCTACAAATTTATCGCT
GTCCGCCTGCCATACGGAGTGCAAGCTGATGAAGCAGATGCTCAAAAAGCCCTAGCCTTCATCCAGCCAGATGTCAGCTT
GGTTGTGAATATCAAGGAATCAGCTGATGCCATGACAGCTGCAGTTGAAGCGACAGGTAGTCCTGTTTCAGACTTCAACA
AGGGGAATATCAAGGCACGTTGCCGTATGATTGCTCAGTATGCCCTTGCTGGTTCCCATAGCGGAGCGGTCATTGGAACA
GACCACGCCGCGGAAAATATCACAGGTTTCTTTACCAAGTTTGGTGACGGCGGTGCGGATATTCTCCCTCTTTACCGCCT
CAATAAACGCCAAGGAAAACAGCTCTTGCAGAAACTTGGCGCAGAGCCAGCCCTTTATGAAAAAATCCCAACGGCAGACC
TAGAAGAAGATAAACCAGGCCTAGCTGACGAAGTCGCACTTGGAGTCACCTACGCAGAGATTGACGACTACCTAGAAGGC
AAAACAATCAGCCCAGAAGCTCAAGCGACCATTGAAAACTGGTGGCACAAAGGCCAACACAAACGCCACTTACCCATCAC
CGTATTTGATGACTTTTGGGAGTAA

Protein sequence :
MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFVLGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIA
VRLPYGVQADEADAQKALAFIQPDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDKPGLADEVALGVTYAEIDDYLEG
KTISPEAQATIENWWHKGQHKRHLPITVFDDFWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 1e-63 58