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Name : nrdF (SP_1180) Accession : NP_345649.1 Strain : Streptococcus pneumoniae TIGR4 Genome accession: NC_003028 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit beta Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0208 EC number : 1.17.4.1 Position : 1118577 - 1119539 bp Length : 963 bp Strand : + Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE DNA sequence : ATGGAAACTTACTACAAAGCCATTAACTGGAATGCCATCGAAGATGTCATCGACAAATCAACTTGGGAAAAACTGACGGA GCAATTTTGGCTCGATACACGTATTCCCTTATCAAACGACTTGGATGACTGGAGAAAGCTATCTAACAAAGAGAAAGACT TGGTCGGAAAAGTTTTTGGTGGTTTAACCCTTCTTGACACTATGCAATCTGAAACTGGGGTTCAAGCCCTTCGCGCAGAC ATCCGTACACCACATGAGGAAGCTGTCTTCAATAACATCCAATTTATGGAATCTGTCCACGCTAAATCTTACTCATCAAT CTTTTCTACCTTGAATACTAAGGCTGAGATTGAAGAAATTTTCGAATGGACCAATACCAATCCTTACCTACAAAAGAAGG CTGAGATTGTCAACGAAATCTACCTAAACGGCAGCCCACTTGAAAAGAAAGTTGCCAGCGTCTTCCTCGAAACCTTCCTC TTCTACTCTGGTTTCTTCACTCCCCTCTACTATCTCGGTAACAACAAACTTGCCAACGTTGCAGAAATCATTAAATTGAT TATTCGTGACGAGTCTGTTCACGGAACCTACATTGGTTACAAATTCCAACTTGGTTTCAATGAATTACCTGAAGAAGAGC AAGAAAAACTCAAAGAATGGATGTACGACCTACTCTATACTCTTTATGAAAATGAAGAAGGCTACACAGAGAGTCTTTAT GACGGTGTTGGTTGGACTGAAGAGGTTAAAACCTTCCTTCGCTACAATGCCAATAAAGCTCTCATGAACATGGGACAAGA TCCACTTTTCCCAGATTCAGCTGAAGATGTCAACCCAATCGTTATGAACGGTATTTCAACAGGAACTTCCAACCATGACT TCTTCTCTCAAGTCGGAAATGGTTACCTTCTTGGCGAAGTTGAAGCCATGCAAGATGATGACTACAACTACGGTTTGCAC TAA Protein sequence : METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRAD IRTPHEEAVFNNIQFMESVHAKSYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLKEWMYDLLYTLYENEEGYTESLY DGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAEDVNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1479 | YP_001800873.1 | ribonucleoside-diphosphate reductase subunit beta | Not tested | Not named | Protein | 8e-72 | 50 |
