Gene Information

Name : SP_1179 (SP_1179)
Accession : NP_345648.1
Strain : Streptococcus pneumoniae TIGR4
Genome accession: NC_003028
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1116230 - 1118389 bp
Length : 2160 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGGGATTAAAACATCTTGAAGACGTGACTTACTTCCGTCTTAATAACGAAATTAACCGTCCTGTTAATGGACAAATCAT
GCTTCATAAAGACAAGGAAGCCTTGGATGCTTTCTTTAAAGAAAATGTAGTTCCAAACACTATGGTTTTTGATTCAATCA
AAGACAAAATCAATTACCTCATTGAACACAACTACATCGAAACAGCCTTTATCAAGAAATACCGTCCAGAGTTCTTGGAA
GAATTAGCTCAATTTATCAAAGACCAAAACTTCCAATTCAAGTCATTCATGGCAGCTTATAAATTTTACAATCAATATGC
CTTAAAGACTAATGACGGTGAATACTATCTTGAAAATATGGAAGACCGTGTCTTCTTCAATGCCCTTTATTTCGCTGATG
GGAATGAAGCTGTTGCAATCGATATTGCCAATGAAATCATCCACCAACGCTACCAACCTGCTACTCCTTCCTTCTTGAAT
GCTGGACGTGCTCGTCGTGGGGAGTTGGTATCTTGTTTCCTAATCCAAGTGACGGATGATATGAACTCTATCGGGCGTTC
TATCAACTCAGCTCTTCAACTTTCACGTATTGGTGGTGGTGTGGGAATTACCCTCAGCAACCTTCGTGAAGCTGGTGCAC
CTATCAAAGGCTATGAAGGAGCTGCTTCAGGTGTCGTTCCTGTTATGAAGCTTTTTGAAGACAGCTTCTCTTACTCCAAC
CAATTGGGGCAACGTCAAGGTGCTGGTGTTGTCTACCTCAACGTCTTTCACCCAGATATCATCGCTTTCCTTTCAACTAA
GAAAGAAAACGCTGATGAAAAAGTACGTGTCAAGACTCTATCACTTGGTGTTGTAGTACCTGATAAATTCTACGAATTGG
CTCGTAAAAATGAAGAAATGTACCTCTTCAGCCCTTACTCTGTAGAAAAAGAATACGGTGTGCCATTCAATTACATCGAC
ATTACTGAAAAATACGATGAATTGGTCGCAAATCCAAATATTCGCAAGACAAAAATCAAGGCGCGGGATTTGGAAACTGA
AATCTCTAAATTGCAACAAGAGTCTGGCTATCCTTATGTAGTCAACATCGATACGGCTAACCGTGCAAATCCTGTTGATG
GAAAGATTATCATGAGTAACTTGTGTTCTGAGATTCTTCAAGTTCAAGAACCAAGCTTGATCAACGATGCTCAAGAATTC
CTTCAAATGGGAACAGATGTTTCATGTAACCTGGGTTCAACCAACGTGGTTAACATGATGACTTCACCTGATTTTGGTCG
TTCTATCCGTGCTATGGTTCGTGCCCTTACTTTCGTTACAGATAGTTCACATATCGTAGCTGTACCAACGATTGACCATG
GAAATAGCCAAGCCCACACCTTTGGTCTCGGTGCCATGGGACTGCACAGCTACCTTGCCCAACAACTCATTGAATATGGT
TCACCTGAGTCTGTTGAATTTACAAGCATCTACTTTATGCTTATGAACTACTGGACCTTGGTAGAGTCAAACAATATTGC
ACGTGAACGTGGTATTACCTTCCACAACTTTGAAAAATCAGACTATGCTAACGGAAGTTACTTTGACAAGTATGTAACTG
GTGAATTTGTTCCAACATCAGACCGTGTTAAAGAACTCTTCAAAAATGTCTTTATCCCTGGTGTTGCTGATTGGGCTGAA
CTTCGCGACAAGGTTCAAGAAGATGGTCTTTACCACCAAAATCGCCTTGCTGTAGCGCCAAATGGTTCTATCAGCTATAT
CAACGACGTTTCTGCTTCTATCCACCCGATTACGCAACGTATCGAAGAACGCCAAGAGAAGAAAATTGGTAAAATCTATT
ACCCTGCTGCTGGCTTGTCTACAGAAACCATTCCTTACTACACTTCTGCCTACGATATGGATATGCGTAAAGTCATCGAT
GTTTACGCTGCTGCGACTGAACACGTGGATCAAGGACTTTCACTCACCCTCTTCATGCGCAGTGACATTCCAAAAGGCCT
TTACGAATGGAAGAGGGAAAATAAACAAACGACACGTGACTTGTCCATCCTTCGTAACTATGCCTTTAACAAGGGAATCA
AGTCTATCTACTACGTCCGTACCTTTACAGATGACGGTGGAGAAGTCGGCGCCAACCAATGTGAAAGCTGTGTGATTTAG

Protein sequence :
MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLE
ELAQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYID
ITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEF
LQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAE
LRDKVQEDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVID
VYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 3e-178 52