Gene Information

Name : smpB (WD0767)
Accession : NP_966523.1
Strain : Wolbachia endosymbiont of Drosophila melanogaster wMel
Genome accession: NC_002978
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 740542 - 740991 bp
Length : 450 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGAAGTTATTGCAGAAAATAGGAAAGCAAGGTTTGAATATTTCATCTTAGAAGAATTTGAAGCGGGTATGGTCTTATT
AAGCAGTGAAGTTAAATCGCTAAGAGAAAGAAAAGTAAATATTTCCGACGCCTACGTTGTTGAAAAGAATAGCGAAGTAT
GGCTGCACAATATGCATATTGCAGAATATAAAGCTGCGAACCGAAAAAATCATAAACCAAAAAGGGAACGTAAATTACTC
TTGCATAAAAAGGAGATAAATAAACTAATTGGTCAAATCAAGACTGCTGGGATAACTGTTGTGCCGCTTTCGGTCTATTT
TAACGATAAAGGATTTGCAAAAACTAAAATTGCCATTGTAAAAGGAAAAAAACTCTACGATAAGAGAGCAACCATAAAAC
AGAGAGAGTGGGATCGTGAAAAAAGTAGATTGTCTAAGAATAATTTATAG

Protein sequence :
MEVIAENRKARFEYFILEEFEAGMVLLSSEVKSLRERKVNISDAYVVEKNSEVWLHNMHIAEYKAANRKNHKPKRERKLL
LHKKEINKLIGQIKTAGITVVPLSVYFNDKGFAKTKIAIVKGKKLYDKRATIKQREWDREKSRLSKNNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-21 50
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-18 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 7e-21 46