Gene Information

Name : hemC (WD0542)
Accession : NP_966318.1
Strain : Wolbachia endosymbiont of Drosophila melanogaster wMel
Genome accession: NC_002978
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 526782 - 527660 bp
Length : 879 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCTAGTCAAAATAGGTACCAGAGGAAGCAAGCTTGCAGTTGCCCAGGCTTTGGAAGCAAAACAAAAGTTGCTGGATTC
TTTTCCTAACTTATCTATTGAAATTGTTAAAATAAAAACTTCTGGAGATAAGTATGCAAACGCAAATCTTGCTGAAATAG
GAGGCAAAGGATTATTCATTAAAGAAATTGAGACTGAATTGCTCGAAAATAATATAGACATGGCAGTTCATTCGCTAAAA
GATATGCCTGCGTTTTTCTCAGGGGGTTTAACAATTCCTTGTGTTTTAGAAAGGCTAAGTTCATGCGATGCGTTTATTTC
TCATAAACACAATAGCCTTGAGTCTTTGCCACAGCAGGCTACTATTGCCACTTCTTCAATAAGAAGAAAAGTTCAGTTGT
TAAATGTTAGACCAGATTTAAATATAGTACCGCTACGTGGAAATGTAACAACCAGATTGCAAAATCAAAGTTTTGATGGA
ATAATTCTAGCTGAAGCAGGACTCATAAGATTAGAAAAACATCACTTGATTACAGAGGTATTGCCACCAAAAGTTATGTT
AAGTGCAGTGGGGCAGGGGGCGGTTTGTATTCAATGTAGAAGGAATGATGTAAAAATTATCGATCTTTTAGAGAAAATTA
ATAATAATATGTCTTTTATAGGAGTGAAATCAGAGCGCAGTTTTATGAAGACAGTGAATGGTTCATGTTTTACACCACTT
GCAGCTTTGGCTGAATATGTGAGCGAAAATATGCTACACCTTCGTTGTATGTTAGCAAGTGGAAAAAATATATACTTCAC
TGAGCGCACTTCATTTATAGAAGATGCGGAGAAAATGGGTATGGATGCAGGATTAGAGTTGAAATCAAAATGCTTATAA

Protein sequence :
MLVKIGTRGSKLAVAQALEAKQKLLDSFPNLSIEIVKIKTSGDKYANANLAEIGGKGLFIKEIETELLENNIDMAVHSLK
DMPAFFSGGLTIPCVLERLSSCDAFISHKHNSLESLPQQATIATSSIRRKVQLLNVRPDLNIVPLRGNVTTRLQNQSFDG
IILAEAGLIRLEKHHLITEVLPPKVMLSAVGQGAVCIQCRRNDVKIIDLLEKINNNMSFIGVKSERSFMKTVNGSCFTPL
AALAEYVSENMLHLRCMLASGKNIYFTERTSFIEDAEKMGMDAGLELKSKCL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-43 45
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-43 45