Gene Information

Name : tkt (WD0387)
Accession : NP_966179.1
Strain : Wolbachia endosymbiont of Drosophila melanogaster wMel
Genome accession: NC_002978
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 369209 - 371281 bp
Length : 2073 bp
Strand : -
Note : Identified by similarity to EGAD:10074; match to TIGR00232 protein family HMM TIGR00232; match to PF00456 protein family HMM PF00456; match to PF02779 protein family HMM PF02779; match to PF02780 protein family HMM PF02780

DNA sequence :
ATGAATCATTCACATTTAAAATCTATGGCAAACGCCATCCGTTTTTTATCAATTGATGCAGTACAAAAAGCAAACTCTGG
ACACCCAGGTATGCCACTTGGCATGGCAGATGTTGCAACTGTTTTGTTTGCTAAATATCTGAATCATAATCCTGATGATT
CTAAATGGTTCAATAGAGATCGCTTTGTTTTATCAAACGGTCATGGGTCAATGTTACTATACTCAATATTATATTTGACA
GGTTATATTAGCGTAGATGAGCTAAAAAACTTCAGACAAATGGGATCCAAGACCCCAGGTCATCCAGAGTTCGGCTTGAC
TTCCGGGGTAGAGGCAACAACAGGCCCGCTCGGTCAGGGGTTTGCCGCTGCTGTTGGCATGGCACTTGCTGAATCGATAC
TTGAAAAGCAGTTTAGAATCAATCACTACACTTATGTGATGCTAGGGGATGGCTCTCTTATGGAAGGAATAAGCCATGAA
GCAGCATCACTTGCTGGGCATCTTAAATTGAATAAGCTTATAGCTCTTTTTGATGATAATGATATTTCTATAGATGGCGC
TACTTGCCTTTCCTGTTCTGACGATGTAGAGAAACGCTTCTTAGCGTATGGATGGAATGTTGACAAAATTGATGGCCATG
ATTTTGATGCCATATCCCTTGCAATAGAGCAAGCAAAAAAGTCTGATAAACCTACAATGATCTGCTGCAAAACTATTATC
GGAAAATTTTCAAGCCGTGCTGGCACATCCTCTGCTCACAGTGGTGCTTTTTCGGAGGAAGACATAAAACAGATGAGAGA
GAAATTAAACTGGAATTATGAACCATTCCATGTACCAGAAGATGTGAAAAATGCCTGGAAGAAAACTGTTGAGAGAGCAA
AACAAAACTACACGATGTCATTCCAGCGCGTGACGCTGGAATCCAGGAAAGAAGAAAAAGAATGGATCCCAGTGTCAAGC
ACTGGGATGACAAGAGAGAGTACTGGGATGACAGAAGAGAATGCTGGGATGACAGGGTATCATGCAGAACTTCAAAGACG
GTTAGATAAACATCTACCAGATAATATCGCTGGTGTTTTAGCTGACCTGAAGAAACAAATATGTGAGCTAATGCCAAACG
AAGCTACTCGATCTTCTTTCGGCAGAGTAATGGAACTTTTAACTGAGTCTATGCCGGAATTAATCGGCGGTTCTGCTGAT
CTTACCGGGTCAAATTGCACTAAATATGAGCACATGCAGGTAATAAATAGCAATAATTATAGTGGCTCTTATGTCCACTA
TGGAGTGAGAGAGCACGCTATGGCAGCATGTATGAATGGTATGGCACTTCACGGCGCGATTCTTCCTTATGGCGGCACTT
TTTTGGTATTTTCCGACTATTGTCGTCCTGCTATACGTCTTTCAGCTCTGATGAAGCAGCAGGTTATGTATGTCATGACT
CACGACTCAATTGGAGTGGGAGAAGATGGCCCGACTCATCAGCCAATAGAGCATTTAGCCTCTTTGCGTGCTATACCAAA
TCTATATGTTTTTAGGCCAGCCGATGCAGTTGAAACTCTGGAGTGTGTTAGCATTGCACTCGAAAAGAAAGAATCTCCAG
CACTGTTTGCGCTCTCAAGGCAAAACGTAAGTTACATGCGCAAGTTCTACTCTGATATCGATCAATCTGCTAATTTATCG
AAGTTTGGTGCATATATTTTGTGTGAATGTTCAAAAGAATTAAAAGTGACGATATTTGCTACGGGGTCCGAGGTTGAAAT
TGCAGTTGAAGCAAGGGAGAAATTGCAGGAAAAGGGTATAGGTACAAGGATTGTTTCTATGCCATGCTGGAGGCTTTTTG
ACGAGCAAAGCGATGAATATAAAGCGGCAATATTAAATAATGACAGCATTAAAGTTGCAATTGAAGCCGGAAGTGAAATG
GGTTGGCATAAATATATAGGTTCAAACGGTATATTTATTGGCATGAAAAGCTTCGGAGAATCAGCACCTTATAAAACACT
CTATGAGCATTTTAATATCAGCGCAGATCATGTGGTAAAATGTGTGTGTGAGAAACTGGTTTACATTCAGTAG

Protein sequence :
MNHSHLKSMANAIRFLSIDAVQKANSGHPGMPLGMADVATVLFAKYLNHNPDDSKWFNRDRFVLSNGHGSMLLYSILYLT
GYISVDELKNFRQMGSKTPGHPEFGLTSGVEATTGPLGQGFAAAVGMALAESILEKQFRINHYTYVMLGDGSLMEGISHE
AASLAGHLKLNKLIALFDDNDISIDGATCLSCSDDVEKRFLAYGWNVDKIDGHDFDAISLAIEQAKKSDKPTMICCKTII
GKFSSRAGTSSAHSGAFSEEDIKQMREKLNWNYEPFHVPEDVKNAWKKTVERAKQNYTMSFQRVTLESRKEEKEWIPVSS
TGMTRESTGMTEENAGMTGYHAELQRRLDKHLPDNIAGVLADLKKQICELMPNEATRSSFGRVMELLTESMPELIGGSAD
LTGSNCTKYEHMQVINSNNYSGSYVHYGVREHAMAACMNGMALHGAILPYGGTFLVFSDYCRPAIRLSALMKQQVMYVMT
HDSIGVGEDGPTHQPIEHLASLRAIPNLYVFRPADAVETLECVSIALEKKESPALFALSRQNVSYMRKFYSDIDQSANLS
KFGAYILCECSKELKVTIFATGSEVEIAVEAREKLQEKGIGTRIVSMPCWRLFDEQSDEYKAAILNNDSIKVAIEAGSEM
GWHKYIGSNGIFIGMKSFGESAPYKTLYEHFNISADHVVKCVCEKLVYIQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-135 48
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 7e-133 44