Gene Information

Name : kdsB (MCA0635)
Accession : YP_113150.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 670473 - 671246 bp
Length : 774 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGCCGGCGGATTTCACCATCGTCATTCCGGCGCGCTACGGTTCGACCCGGCTGCCCGGCAAGCCTCTGTTGGAACTCGG
CGGCAAGCCGATGATCGCGCACGTCTGCGAGCGGGCGCTCGAAGCCGGTGCGGCGGAGGTCGTGGTGGCGACCGACGACG
CGCGCATCGCCGAGGCGGTGGACGGCCTGCCGGTCACCGCGATGCTGACCCGGACCGAACATGCCAGCGGCACCGAGCGC
CTGGCCGAGGTGGCCGAGCGCCGGGCCTGGAGCGACGATACCCTCGTGGTCAACCTGCAGGGTGACGAGCCTTTCATGGA
CGCCGCCCTGCTGCGCGCCCTGGCAGAGGCGCTGGGGCGGCGCGAAGACTGCCGGGTGGCGACCCTGGCCGCGCCGATCC
ACCGGCCCGAGGAAATCTTCGATCCCAACGTGGTCAAGGTGGTCACCGACGGTGAGAACCGGGCGCTGTATTTCAGCCGC
GCTGCCGTGCCTTGGGACCGCGAGTCCTTCGCCGAAGGAGCGGGGGTGCCGATGCCGGGCATGCCTTATCGCCGCCATAT
CGGTGTCTATGCCTACACCGCGTCCTATCTGCGTCGCTACGTGGACTTGGAGCCGTCGCCGCTGGAGCACGTCGAGCGCC
TGGAGCAACTGCGCATCCTCTGGCACGGTGACCGCATCCTGGTGGTGCCGGTGGAGGGCGCGCCTGCACCGGGTGTGGAT
ACGGCCGCCGATCTCGAGCGGGCCCGGCGCCATCTGTCCGGCCGGACACCGTAA

Protein sequence :
MPADFTIVIPARYGSTRLPGKPLLELGGKPMIAHVCERALEAGAAEVVVATDDARIAEAVDGLPVTAMLTRTEHASGTER
LAEVAERRAWSDDTLVVNLQGDEPFMDAALLRALAEALGRREDCRVATLAAPIHRPEEIFDPNVVKVVTDGENRALYFSR
AAVPWDRESFAEGAGVPMPGMPYRRHIGVYAYTASYLRRYVDLEPSPLEHVERLEQLRILWHGDRILVVPVEGAPAPGVD
TAADLERARRHLSGRTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-21 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-21 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-21 43