Gene Information

Name : hemC (MCA3060)
Accession : YP_115447.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3244910 - 3245965 bp
Length : 1056 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGTGGAACGCCGAACGCTGAGCGGACCACCGCCCCACGGAACGCCGGTACCAGGATTTCGGCCCGGCAAATCGCGATC
TGTTAAAATGCGCGGATCGTCTTTTCCAGGTTTTCCTTCGACCGTGGCCAGTCACACCCTCCGCATAGCGACCCGCAAGA
GCCCACTGGCTTTGTGGCAGGCAGAATACGTCGCATCCCGTCTTCGGGCAGCCCACCCCGACCTCCGGGTCGAACTGGTC
GGGATGACCACCCGGGGCGACAAACTGCTCGATGCTCCACTCGCGAAAGTGGGCGGCAAGGGGTTGTTCGTGAAGGAGCT
GGAACAGGGCCTGCTCGAGGGCAGGGCCGACATCGCCGTCCATTCCATGAAGGACGTGCCAGTCGAATTCCCCGAAGGGC
TCCATCTCGCCGCCATCCTGGAACGCGAAGACCCGCGTGACGCTCTGGTCTCCCACCGTTACCGGAGCTTCGCGGAGTTG
CCGGCCGATGCCCGCATCGGCACCTCCAGCCTGCGGCGCCAGTGCCAGATCAAATGCCGCCTCCCCGGCTGCTCCCTGTA
CGATCTGCGCGGCAACGTCAACACCCGGCTCGCCAAACTGGACGCGGGTGAGTTCGACGCCATCGTGCTCGCCTCTGCCG
GCCTGAAACGGCTCGGCTTCCAGGAACGTATCGCCGAAACACTGACACCGGAACAATGCCTCCCGGCCATCGGTCAAGGG
GCGATCGGCGTGGAGTGCCGGAGCACCGATACCCGGACCAACGCCCTGCTGGTGCCGCTGCACCATCCGCCCACGGCGTG
GTGCGTCCTGGCCGAACGCGCCATGAACCGACGCCTCGACGGCGGCTGCCAGGTTCCGATCGCCGGTTTCGCCCAGCTCG
AAGGCGACACCCTGAGCCTGCGCGGACTGGTCGGCAACCCGGACGGCTCGGGCATCATCCGCGCCGAAGCCGTCGGTCAC
CCGTCCACCTTCGAGGCACTGGGAAAGCGGGTCGCCGAGCATCTGCTCGACCAGGGCGCCGACGAAATACTCCGGCGCGT
TTACGCCACACCCTGA

Protein sequence :
MVERRTLSGPPPHGTPVPGFRPGKSRSVKMRGSSFPGFPSTVASHTLRIATRKSPLALWQAEYVASRLRAAHPDLRVELV
GMTTRGDKLLDAPLAKVGGKGLFVKELEQGLLEGRADIAVHSMKDVPVEFPEGLHLAAILEREDPRDALVSHRYRSFAEL
PADARIGTSSLRRQCQIKCRLPGCSLYDLRGNVNTRLAKLDAGEFDAIVLASAGLKRLGFQERIAETLTPEQCLPAIGQG
AIGVECRSTDTRTNALLVPLHHPPTAWCVLAERAMNRRLDGGCQVPIAGFAQLEGDTLSLRGLVGNPDGSGIIRAEAVGH
PSTFEALGKRVAEHLLDQGADEILRRVYATP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-80 60
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-80 60