Gene Information

Name : tkt-1 (MCA3040)
Accession : YP_115427.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3226183 - 3228195 bp
Length : 2013 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAGGACGCGACGAGAACTCGCCAACGCCATACGCGCCTTGAGCATGGATGCCGTGCAGAAGGCCAACTCGGGCCATCC
CGGGGCGCCGATGGGGATGGCGGACATTGCCGAGGTGCTGTGGAACGACTACCTGTGCCACAACCCGGCCAATCCGAAGT
GGCCCAACCGCGACCGCTTCGTGCTGTCCAACGGCCACGGCTCGATGCTGATCTATTCCCTGCTGCATCTGACCGGCTAC
GATCTGCCCATCGAGGAGCTGCAGAACTTCCGTCAGCTCCACTCCAAAACCCCCGGCCATCCCGAATACGGCTACACCCC
CGGGGTGGAGACCACCACGGGTCCGCTGGGCCAGGGCATCACCAACGCCGTCGGCATGGCCCTGGCCGAGCGCACGCTCG
CCGGCCAGTTCAACCGCCCCGGCCATACCATCGTCGACCATTACACCTACGTCTTCCTGGGCGATGGCTGCCTGATGGAG
GGCATCTCCCACGAGGCCTGCTCGCTGGCCGGCTCCATGAAGCTGGGCAAGCTGATCGCCTTCTACGACGACAACAACAT
CTCCATCGACGGCGAAGTGCGCGGCCATGGCGGCGTGCCCGGCTGGTTCATGGACGATACCCCCCGGCGCTTCGAGGCTT
ACGGCTGGCACGTGATCCCCAAGGTCGACGGGCATGATCCGGACGCCGTGAAGGCGGCCATCGAGGAAGCCCGCGCGGTC
ACCGACAAACCGTCGCTGATCTGCTGCCAGACCATCATCGGCTGGGGTTCGCCCAACAAACAGGGCAAGGAAGACTGCCA
CGGCGCCGCCCTCGGCACCGACGAGGTCGCCTTGACCCGCGAGAACATCGGCTGGTCGCACCCGCCTTTCGAAATCCCGG
CCGACATCTACGAGGCCTGGAGCGCGCGCGAGACCGGCGCCAAGGCCGAAGGCGAGTGGAACGACCGCTTCGAAAACTAC
CGCCGCGAATTCCCCGAGCTGGCCGCCGAGTTCGAACGCCGCATGGCCGGCGAATTGCCCCGCGACTGGGCGGAGAAATC
CGCCGCCTTCGTGGCCCAGGTGAACGAGAAGGCCGAGACCATCGCCAGCCGCAAGGCCTCCCAGAACGCCCTCAACGGCT
TCGGGCCCCTGCTGCCGGAGATCCTGGGCGGCTCGGCCGACCTCGCCGGCTCCAACCTGACCCTGTGGTCCGGCTGCAAG
GACGTCAACGCCCCCGGCCACGACGGCAACTACGTCTACTACGGCGTGCGTGAATTCGGCATGTCCGCCATCATGAACGG
CATCGCCCTGCACGGTGGCTTCAAGCCCTACGGCGCGACCTTCCTGATGTTCTCCGAATACGCCCGCAACGCGCTGCGCA
TGTCGGCCCTGATGAAGATCCCGGTGATCTACGTCTACACCCACGACTCCATCGGCCTGGGTGAGGACGGCCCCACCCAC
CAGCCCGTCGAGCAGACCGCCACCTTGCGCCTCATCCCCAACATGCAGGTCTGGCGGCCGTGCGACGCGGTGGAATCGGC
GGTGGCCTGGAAGTGCGCGATCGAGCGCCGGGACGGTCCCTCCGCCCTGATCTTCTCGCGCCAGAACCTGCCGCACATGC
CCCGCACGCCGGAGCAGATCGCCGCGATCGCCAAGGGCGGCTATGTCCTGGTCGACTGCACCGGCACCCCCGACCTCATC
CTGATGGCCACCGGCTCGGAGGTCGAGCTGGCGGTGAAAGCGGCCGAGGCCCTGACCGCCAAGGGCAGGCAGGTGCGGGT
GGTGTCGATGGCCTCCACCAACGTGTTCGATGCCCAGGAGCCGGCGTACCGCGACAGCGTGCTGCCGCCCGCCGTGACCC
GCCGCCTCGCCATCGAGGCCGGTGTCAGCGACGGCTGGTGGAAATACGTCGGCAGCCATGGCAAAGTTATCGGCCTGGAC
CGCTTCGGCGAATCCGCGCCGGCCGGCGTGCTGTTCAAGACCTTCGGCTTCACCGTCGACAACGTGGTCGGCCAGGCCGA
GGCCTTGTTCTAA

Protein sequence :
MRTRRELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDYLCHNPANPKWPNRDRFVLSNGHGSMLIYSLLHLTGY
DLPIEELQNFRQLHSKTPGHPEYGYTPGVETTTGPLGQGITNAVGMALAERTLAGQFNRPGHTIVDHYTYVFLGDGCLME
GISHEACSLAGSMKLGKLIAFYDDNNISIDGEVRGHGGVPGWFMDDTPRRFEAYGWHVIPKVDGHDPDAVKAAIEEARAV
TDKPSLICCQTIIGWGSPNKQGKEDCHGAALGTDEVALTRENIGWSHPPFEIPADIYEAWSARETGAKAEGEWNDRFENY
RREFPELAAEFERRMAGELPRDWAEKSAAFVAQVNEKAETIASRKASQNALNGFGPLLPEILGGSADLAGSNLTLWSGCK
DVNAPGHDGNYVYYGVREFGMSAIMNGIALHGGFKPYGATFLMFSEYARNALRMSALMKIPVIYVYTHDSIGLGEDGPTH
QPVEQTATLRLIPNMQVWRPCDAVESAVAWKCAIERRDGPSALIFSRQNLPHMPRTPEQIAAIAKGGYVLVDCTGTPDLI
LMATGSEVELAVKAAEALTAKGRQVRVVSMASTNVFDAQEPAYRDSVLPPAVTRRLAIEAGVSDGWWKYVGSHGKVIGLD
RFGESAPAGVLFKTFGFTVDNVVGQAEALF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 71
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 66