Gene Information

Name : lysS (MCA0301)
Accession : YP_112835.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 296343 - 297833 bp
Length : 1491 bp
Strand : -
Note : identified by similarity to SP:P14825; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499

DNA sequence :
ATGAGTGAACTGCAAGACGAAAACAAACTGGTCGCGCTGCGCCGCGAAAAGCTCGGCAAGCTGCGGCAAACAGGGGTCGC
TTTCCCAAATGACTTCCGCCGCGACGCCCTCGCCGCCGAACTACGGGCACGCTACGGGGACGAAACGGCCGAGGCACTGG
AAGAAACCGCCGTATCGGTCAAGCTGGCCGGGCGGCTGATGGGCAAGCGTATCATGGGCAAAGCCAGCTTTGCCCATATC
CAGGACATGTCCGGCCGTATCCAGATTTTCCTGCAGCGCGATGGACTGGCCGAAGGCGTGTACGAGGAGTTCAAGAGTTG
GGACATCGGCGATGTGATCGGCGTGGAAGGCACGGTGTTCCGCACCAAGACCGGCGAGCTGTCGGTGAAGGCATCGAACA
TCCGCCTGCTCACCAAATCACTGCGTCCGCTGCCCGAGAAATTCCACGGCCTGACCGACGCCGAGACCCGCTACCGCCAG
CGCTACCTCGACCTCCTCATGAACGAGGAGTCGCGCCGGGTATTCCAGCTCCGCAGCGCCATCGTGCGCTACATCCGCGA
CTTCTTGAGCGAGCGTGGCTTCATCGAGGCAGAGACGCCGATGATGCAGGTGATCCCCGGCGGCGCCCGGGCCAAACCGT
TCGTCACCCATCATAATGCGCTGGGGCTGGATCTGTATCTGCGCATCGCTCCCGAGCTCTACCTGAAGCGGCTGGTGGTG
GGCGGCTTCGAAAAAGTATTCGAGATCAACCGCAGCTTCCGCAACGAGGGCTTGTCCACTCGGCACAATCCCGAATTCAC
GATGATCGAGTTCTATCAGGCCTATGCCGATTACCGCGACCTGATGGATCTGACCGAAACGCTGATGCGGGGAATCGCGC
AGAACCTGCTGGGCGGCACCGTCGTCACCCATCAGGGCAAGGATTACGATCTGGGCCGGCCGTTCCGGCGCATGACGGTG
CTGGAATCGATCATCCACTACAACCCGGACATCCGGGCCGAAGACTTGGCCGAGCGCGAAAGCGCCGCGGCCATCGCGGC
CGGGCTGGGCATTCCGGTTGCCGCCGGCGACGGACTCGGCAAGATCCAGACCGAAATCTTCGAAAAGACCGTGGAAGACC
GGCTGGATGAACCAACCTTCATCACCGCCTATCCGGCCGAAGTCTCGCCGCTGGCGCGGCGCAACGACGAAAACCCCTTC
ATCACAGACCGCTTCGAGTTTTTCGTGGGCGGGCGCGAGCTGGCGAACGGCTTTTCCGAGCTCAACGACCCGGAAGACCA
GGCGGAACGGTTCAGAAAGCAGGTGGAAGACAAGGCCGCGGGCGACGAGGAGGCCATGCACTACGATGCCGACTACATCC
GCGCGCTCGAATACGGCCTACCGCCCACCGCGGGCGAGGGCATCGGCATCGACCGCCTGGTGATGTTCTTCACCGACTCT
CCCTCGATCCGCGACGTCATCCTGTTCCCGCACATGCGGCCCGAAAGCTGA

Protein sequence :
MSELQDENKLVALRREKLGKLRQTGVAFPNDFRRDALAAELRARYGDETAEALEETAVSVKLAGRLMGKRIMGKASFAHI
QDMSGRIQIFLQRDGLAEGVYEEFKSWDIGDVIGVEGTVFRTKTGELSVKASNIRLLTKSLRPLPEKFHGLTDAETRYRQ
RYLDLLMNEESRRVFQLRSAIVRYIRDFLSERGFIEAETPMMQVIPGGARAKPFVTHHNALGLDLYLRIAPELYLKRLVV
GGFEKVFEINRSFRNEGLSTRHNPEFTMIEFYQAYADYRDLMDLTETLMRGIAQNLLGGTVVTHQGKDYDLGRPFRRMTV
LESIIHYNPDIRAEDLAERESAAAIAAGLGIPVAAGDGLGKIQTEIFEKTVEDRLDEPTFITAYPAEVSPLARRNDENPF
ITDRFEFFVGGRELANGFSELNDPEDQAERFRKQVEDKAAGDEEAMHYDADYIRALEYGLPPTAGEGIGIDRLVMFFTDS
PSIRDVILFPHMRPES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-137 59
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-80 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_112835.1 lysyl-tRNA synthetase VFG1668 Protein 3e-137 59