Gene Information

Name : thiC (MCA2710)
Accession : YP_115111.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2895662 - 2897536 bp
Length : 1875 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCGCGATCCCCCAAGAAATCCTGCACGAGGCCGTCACCGCCAAGAAAGCCTCGATCCAGCCGTTCGCGGCCTCGGA
AAAAGTCTACCTCCAGGGCAGCCGCCCGGACCTGCGCGTCCCAATGCGCAAGATCAGCCAGTCGGACACGCCCACCAACA
CGGGCCGGGAAAAGAACCCGCCAGTCTATGTCTACGACACCTCCGGCCCCTATACCGACCCCACCGTATCGGTCGACCTG
AGACTGGGCCTGCCGCCCTTGCGCGAGCCCTGGATCGAGGAACGCGGGGACACCGAGCTGCTGAAGGGGCCCTCGTCGTC
CTACGGCCTTCAGCGCCAGCGCGATCCGGCTCTGGCGTCCCTGCGCTTCGAGCATATCCGCGCGCCCCGCCGGGCGAAGG
GCGGCGCCAACGTCACCCAGATGCACTACGCCAGGCAGGGCATCATCACGCCGGAGATGGAGTTCGTCGCCATCCGCGAG
AACCAGAAACTGGAAGCGCTGGCGGAGACATACAAGTTCCAGCATCCGGGAGAAGCCTTCGGCGCGGCCATCCCCCAGGT
CATCACCCCCGAATTCGTCCGCGACGAAGTCGCCCGCGGCCGGGCCATCATCCCCAGCAACATCAACCACCCGGAATCGG
AGCCGATGATCATCGGCCGCAACTTTCTGGTGAAGATCAACTGCAACCTCGGCAATTCCGCCGTCAGCTCTTCGATAGAA
GAGGAAGTGGAAAAGATGCTGTGGGCGATCCGCTGGGGCGGCGACACGGTGATGGACCTGTCCACGGGCAAGAACATCCA
CGAGACCCGCGAATGGATCATCCGCAATTCCCCGGTGCCCATCGGCACCGTGCCGATCTACCAGGCGCTGGAAAAGGTGG
ACGGCAAGGCCGAGGAGCTGACCTGGGAAATCTTCCGCGACACGCTGATCGAGCAGGCCGAGCAGGGGGTGGACTATTTC
ACCATCCATGCCGGCATCCGCCTGCCCTTCATCCCGCTGACCGCCAAGCGCACCACCGGCATCGTGTCCCGGGGCGGCTC
CATCATGGCCAAATGGTGCCTGGCCCACCACAAGGAGAGCTTCCTCTACACCCATTTCGAGGACATCTGCGAGATCATGA
AGGCCTACGACGTGGCCTTCTCCCTGGGTGATGGCCTGCGCCCCGGTTCCATCGCCGATGCCAACGACGAGGCTCAGTTC
GCGGAATTGCGCACCCTGGGCGAGCTGACCCGGATCGCCTGGAAGCACGACGTGCAGGTGATGATCGAAGGTCCCGGCCA
CGTGCCCATGCACATGATCAAGGCCAACATGGAGGAGCAGCTCAAGCATTGCCACGAGGCGCCCTTCTACACCCTGGGAC
CCTTGACCACCGACATCGCGCCGGGCTACGACCACATCACCTCGGCCATCGGCGCCGCCATGATCGGCTGGTACGGCACG
GCCATGCTGTGCTACGTCACGCCCAAGGAGCATCTGGGCCTGCCGAACAAGCAGGACGTGCGCGACGGCATCATCGCCTA
CAAGATCGCCGCCCACGCTGCGGATCTGGCCAAGGGCCACCCCGGCGCCCAGGCGCGCGACAATGCCCTGTCCAAGGCAC
GCTTCGAGTTCCGCTGGCAGGATCAGTTCAACCTGTCGCTGGACCCCGAGAAGGCGTTGGAATTCCATGACGAGACACTG
CCCCAGGAAGGGGCGAAACAGGCGCATTTCTGCTCCATGTGCGGCCCGCATTTCTGCTCGATGAAGATCACCCAGGACGT
GCGCGACTATGCCCGCGAACACGGCCTGGACGAGGCGCAAGCCCTGGCGAAAGGCATGGAAGAAAAATCGGACGAGTTCG
TGAGGTCCGGGGCCGAGGTGTACCAGCGCACCTGA

Protein sequence :
MSAIPQEILHEAVTAKKASIQPFAASEKVYLQGSRPDLRVPMRKISQSDTPTNTGREKNPPVYVYDTSGPYTDPTVSVDL
RLGLPPLREPWIEERGDTELLKGPSSSYGLQRQRDPALASLRFEHIRAPRRAKGGANVTQMHYARQGIITPEMEFVAIRE
NQKLEALAETYKFQHPGEAFGAAIPQVITPEFVRDEVARGRAIIPSNINHPESEPMIIGRNFLVKINCNLGNSAVSSSIE
EEVEKMLWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYF
TIHAGIRLPFIPLTAKRTTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVAFSLGDGLRPGSIADANDEAQF
AELRTLGELTRIAWKHDVQVMIEGPGHVPMHMIKANMEEQLKHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGT
AMLCYVTPKEHLGLPNKQDVRDGIIAYKIAAHAADLAKGHPGAQARDNALSKARFEFRWQDQFNLSLDPEKALEFHDETL
PQEGAKQAHFCSMCGPHFCSMKITQDVRDYAREHGLDEAQALAKGMEEKSDEFVRSGAEVYQRT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 74
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 74
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74