Gene Information

Name : MCA2220 (MCA2220)
Accession : YP_114640.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : 3.5.2.6
Position : 2398506 - 2399354 bp
Length : 849 bp
Strand : -
Note : identified by similarity to SP:P14489; match to protein family HMM PF00905

DNA sequence :
ATGAATATGCCGACTTCCTTGTCGGCTGCAAACGTTCCGCACCCCTGTCGGGGTATGTCGACTCGAATAATGCAAGGGGT
ATTTGCAGCAGCGGTTTTGTTTGCATGCGCAGCGCATGCAGCCGGCTGGAAAGACAGCCGGGAAGTCGGCGATATTTTCA
GACATGCCGGCGTGCATGGCACTTTCGTACTTTATGACGTCTCCGCCCAGACGTTTACCGGTCATGATAGAAAACGCGCA
GAAACCAGATTCATTCCTGCGTCGACGTTCAAGATTCCAAATACTTTGATTGGACTTGCCACCGGCGCGGTCAAGAGCGT
CGATGAAGTCTTGCCCTATGGCGGCGCTCCTCAGCCTTTCAAAAGCTGGGAGAAGGACATGGGGCTGCGCGAGGCGATCG
TGATTTCGAACGTTCCGATCTATCAGGAACTGGCCCGGCGTATCGGTCTCGAGCGCATGAAGGACTATGTATCTCGCCTG
GATTACGGCAACAGGGAAATTGGCTCTGCCGTGGATACGTTCTGGCTGGCCGGGCCGCTCAAGATCAGCGCGGTCGAGCA
AACCCGGTTTCTCGCCAAATTGGCGCTGGGGGAATTGCCGTTTCCGAAAGATATTCAGGGAGCCGTTCGAGAAATCATCC
GATTGGAACAAGGCACGAATTGGAAATTCTATGGCAAAACGGGCTTGGGAAATGTTGCCGGAGTCGGGGTGGGCTGGTGG
GTCGGCTGGGTGCAACGGGACGATCGCGTCTATGCGTTTGCGCTGAACATGGATGTCCGGAGCGAGTCCGACGTGGGCAA
ACGAGTGGAGTTGGGTAAAGCCAGCCTGAAAGCACTGGGGTTGCCTTGA

Protein sequence :
MNMPTSLSAANVPHPCRGMSTRIMQGVFAAAVLFACAAHAAGWKDSREVGDIFRHAGVHGTFVLYDVSAQTFTGHDRKRA
ETRFIPASTFKIPNTLIGLATGAVKSVDEVLPYGGAPQPFKSWEKDMGLREAIVISNVPIYQELARRIGLERMKDYVSRL
DYGNREIGSAVDTFWLAGPLKISAVEQTRFLAKLALGELPFPKDIQGAVREIIRLEQGTNWKFYGKTGLGNVAGVGVGWW
VGWVQRDDRVYAFALNMDVRSESDVGKRVELGKASLKALGLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaOXA-129 AET25386.1 OXA-129 beta-lactamase Not tested PAGI-2(C) Protein 4e-40 45
bla OXA-129 AFG30109.1 OXA-129 beta-lactamase Not tested PAGI-2 Protein 4e-40 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MCA2220 YP_114640.1 beta-lactamase AY306130.1.gene1.p01 Protein 2e-70 66
MCA2220 YP_114640.1 beta-lactamase JF273470.1.gene1.p01 Protein 5e-51 50
MCA2220 YP_114640.1 beta-lactamase EU086834.1.gene1.p01 Protein 9e-50 49
MCA2220 YP_114640.1 beta-lactamase EU086830.1.gene1.p01 Protein 6e-50 49
MCA2220 YP_114640.1 beta-lactamase AY619003.1.gene1.p01 Protein 4e-46 47
MCA2220 YP_114640.1 beta-lactamase AM932669.1.gene2.p01 Protein 3e-40 45
MCA2220 YP_114640.1 beta-lactamase X58272.1.gene1.p01 Protein 9e-39 42
MCA2220 YP_114640.1 beta-lactamase AY665723.gene.p01 Protein 6e-37 42
MCA2220 YP_114640.1 beta-lactamase EF102240.1.gene13.p0 Protein 1e-36 42
MCA2220 YP_114640.1 beta-lactamase NC_010481.6155789.p0 Protein 6e-37 42
MCA2220 YP_114640.1 beta-lactamase DQ519090.1.gene1.p01 Protein 1e-36 41
MCA2220 YP_114640.1 beta-lactamase GU831575.1.gene1.p01 Protein 4e-36 41
MCA2220 YP_114640.1 beta-lactamase AY423074.1.gene1.p01 Protein 6e-31 41