Gene Information

Name : serS (MCA1971)
Accession : YP_114403.1
Strain : Methylococcus capsulatus Bath
Genome accession: NC_002977
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2121755 - 2123038 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGGATCCACGTTTATTCCGCACCCAACTGGAAGAGACCGCACGGCAGCTCGGTCGCCGCGGCTTCGTTCTGGACAC
CGCTGCCTTCGGTGCGCTCGAAGAGCGCCGCAAGGCCCTGCAGGTGGAAACCCAGAACTTGCAGAACGAGCGTAACAGCC
GTTCCAGGTCCATCGGCCAGGCCAAGGCGCGGGGGGAAGACATCGAGCCCTTGCTGGCAGCCGTGCAGGGGCTGGGGGAG
CGGTTGAAGGAAAACGAGGCTGAATTGGCGTCGATCCAGGAACGCATGGAAGCCCTGCTGCTCGGCGTGCCCAATCTCCT
GGACACCGACGTGCCCGAGGGGCGCAGCGAGGCTGACAACGTCGAGATCCGGCGCTGGGGCGAGCCGCCGCAATTCGACT
TCGAACCCAAGGACCACGTCGATCTAGCCGTCGGTCTGGGCTGCGCGGATTTCGAAGCGGCCGCCAAACTGAGCGGTTCG
CGTTTCGTGGTCCTGACCGGGCCACTGGCACGGCTGCAGCGTGCCCTGACGCAGTTCATGCTCGATATTCACACCGGCGA
GCATGGCTACATCGAAACCTACGTGCCGTTCCTGGTCAACGCCGACAGCCTGCGCGGCACCGGTCAGCTCCCGAAGTTCG
AGGAGGACCTGTTCAAGGTCCAGCACGAGCCGGTGTTCTATCTGATTCCGACCGCCGAGGTCCCGGTCACCAATCTGGTG
CGGGACGAGATCGTGGAGGAAGAACGCCTGCCGCTGAAATACGTCTGTCATACACCGTGTTTCCGCAGCGAAGCCGGCTC
CTATGGCCGTGACGTGCGCGGACTGATCCGGCAGCACCAGTTCGAGAAGGTGGAACTGGTCCAGATCGTCCGCCCCGAAG
ACTCGCGCGAGGCCCACGAGGCATTGACCCGCCACGCCGAAGTCATCCTGGAGCGGCTCGGTCTGCCCTACCGGCGTGTG
CTGCTGTGTGCAGGAGACACCGGCTTTTCCTCCGCCAAGACCTACGACCTGGAAGTCTGGCTACCGGGCCAGCAGTCCTA
CCGGGAAATCTCGTCTTGCAGCAATTTCCGCGACTTTCAGGCTCGCCGGCTCCAAGCGCGTTGGCGCAATCCAGAAACCG
GCAAACCGGAGCTGGTCCATACGCTCAACGGTTCGGGACTCGCCGTCGGACGTACCCTGGTCGCGGTCCTGGAGAACTGC
CAGGATGAAGCCGGGCGGATCCGGGTGCCGGAAGTCCTGGTGCCGTACATGGGCGGCGTGAACTTGATCGGCCCCGCCGC
ATGA

Protein sequence :
MLDPRLFRTQLEETARQLGRRGFVLDTAAFGALEERRKALQVETQNLQNERNSRSRSIGQAKARGEDIEPLLAAVQGLGE
RLKENEAELASIQERMEALLLGVPNLLDTDVPEGRSEADNVEIRRWGEPPQFDFEPKDHVDLAVGLGCADFEAAAKLSGS
RFVVLTGPLARLQRALTQFMLDIHTGEHGYIETYVPFLVNADSLRGTGQLPKFEEDLFKVQHEPVFYLIPTAEVPVTNLV
RDEIVEEERLPLKYVCHTPCFRSEAGSYGRDVRGLIRQHQFEKVELVQIVRPEDSREAHEALTRHAEVILERLGLPYRRV
LLCAGDTGFSSAKTYDLEVWLPGQQSYREISSCSNFRDFQARRLQARWRNPETGKPELVHTLNGSGLAVGRTLVAVLENC
QDEAGRIRVPEVLVPYMGGVNLIGPAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-98 51