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Name : merA (MCA1340) Accession : YP_113802.1 Strain : Methylococcus capsulatus Bath Genome accession: NC_002977 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : 1.16.1.1 Position : 1424708 - 1426396 bp Length : 1689 bp Strand : + Note : identified by similarity to SP:P94702; match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF02852; match to protein family HMM TIGR02053 DNA sequence : ATGAGTAGGCATGAGTTGCTCATCGACGGCATGACCTGCACGTCATGCGCCGAGCACGTCCGGCAGGCTCTGGAAAAGGT GCCCAGCGTGCGCTCGGCCTCAGTGTCGTTTCCGCGTAAACGCGCCGAGATCGAGGCGGATCCGGGCGTGGGCCCGGATC CGCTGGTCGCGGCCGTGACCGCGCTCGGCTACCGCGCACGGGTTTCCGATACACCGGGCAAGTCCGCCGGCGGCTTGTTC GACGAGACGTTCGGCTGCCCGGACGGCGGAACGAAGCGCGTTAGCGGCGAGCCAGCACTGCACGTGACCGTGATCGGCAG CGGCGGCGCGGCAATGGCGGGTGCATTGAAGGCCGTGGAGCTCGGCGCGCGCGTGACGCTGATCGAGCGCGGCACCATAG GCGGCACCTGCGTCAATGTCGGCTGCGTGCCCTCGAAGATCATGATTCGCGCCGCCCACATCGCCCACCTGCGCCGCGAA AGCCCGTTCGATGAGGGGCTTCCGCCGACACCGCCGGTCGTCCTGCGCGAGCGGCTGTTGGCCCAGCAGCAAGGCCGCGT CGAGGAACTGCGCCACGCCAAGTACGAAGGCATCCTGGCGAGTACCCCGGCAGTCACCGTGCTGCGCGGCGAGGCCAGGT TCATGGATGCGCATACGCTCACCGTGGCGCTTTGCCACGGCGGCACGCGCGAGCTGAGCTTCGACCGTTGCCTCGTCGCC ACCGGCGCGAGTCCGGCGATTGCGCCGATCCAGGGCCTTGCGGATACGCCTTACTGGACTTCCACCGAGGCGCTGGCGAG CGACACGATCCCCGAGCGGCTGGCCGTGATCGGTTCGTCGGTGGTGGCGGTCGAGCTGGCGCAGGCCTTCGCCCGGCTGG GCAGCCGGGTCTCGATACTGGCGCGCCGCACGCTGTTCTTCCGCGAAGATCCGGCCATTGGCGAGGCCGTAACAAACGCG TTCCGTTTGGAAGGCATCGAGGTGCTGGAGCATGCCCAGGCGAGCCAGGTCGCCTATGCGAACGGGGAATTCGTGATGAC TACCGGTCACGGCGAGCGGCGCGCCGACAAGCTGCTGGTTGCCACCGGGCGCGCGCCGAACACGCGCAACCTGAATCTCG AAGCGGCGGGCATCAAGGTCGACGCCCAAGGGGCCATCATCGTCGACCGCGCCATGCGCACCAGCGCGCCGCACATCTTT GCTGCCGGCGACTGCACCGACCAGCCGCAATTCGTGTATGTGGCGGCGGCGGCCGGTAGCCGCGCCGCGATCAACATGAC GGGCGGCAGTGCCGAGCTGGATCTGACGACGATGCCGAAGGTGACGTTCATCGATCCACAGGTGGCAACGGTGGGCTACA GCGAAGCCGAAGCGCGCCACGACGGCATCGAGACCGTGAGCCGCACCCTCACGCTCGACAACGTGCCGAGGGCGCTGGCC AATTTCGACACCCGCGGCTTCATCAAGCTGGTGGCCGAAGCCGGCACTGGGCGTCTGATCGGCGTGCAGGCAGTGGCTCC GGAGGCGGGCGAATTGATCCAGGCGGCCGCGCTGGCGATCCGCCACCGGATGACCGTGCAGGAATTGGCCGACCAGTTGT TTCCCTATCTGACCATGGTCGAGGGTCTGAAGCTCGCGGCCCAGACCTTCACCAAGGACGTCAAACGGCTTTCCTGCTGT GCCGGGTGA Protein sequence : MSRHELLIDGMTCTSCAEHVRQALEKVPSVRSASVSFPRKRAEIEADPGVGPDPLVAAVTALGYRARVSDTPGKSAGGLF DETFGCPDGGTKRVSGEPALHVTVIGSGGAAMAGALKAVELGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRE SPFDEGLPPTPPVVLRERLLAQQQGRVEELRHAKYEGILASTPAVTVLRGEARFMDAHTLTVALCHGGTRELSFDRCLVA TGASPAIAPIQGLADTPYWTSTEALASDTIPERLAVIGSSVVAVELAQAFARLGSRVSILARRTLFFREDPAIGEAVTNA FRLEGIEVLEHAQASQVAYANGEFVMTTGHGERRADKLLVATGRAPNTRNLNLEAAGIKVDAQGAIIVDRAMRTSAPHIF AAGDCTDQPQFVYVAAAAGSRAAINMTGGSAELDLTTMPKVTFIDPQVATVGYSEAEARHDGIETVSRTLTLDNVPRALA NFDTRGFIKLVAEAGTGRLIGVQAVAPEAGELIQAAALAIRHRMTVQELADQLFPYLTMVEGLKLAAQTFTKDVKRLSCC AG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 0.0 | 84 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 0.0 | 77 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 0.0 | 77 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 0.0 | 76 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 0.0 | 76 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 0.0 | 76 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 0.0 | 75 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 0.0 | 74 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 0.0 | 74 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 0.0 | 74 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 4e-90 | 41 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 6e-90 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| merA | YP_113802.1 | mercuric reductase | BAC0653 | Protein | 0.0 | 78 |
| merA | YP_113802.1 | mercuric reductase | BAC0652 | Protein | 0.0 | 75 |
| merA | YP_113802.1 | mercuric reductase | BAC0650 | Protein | 2e-172 | 66 |
| merA | YP_113802.1 | mercuric reductase | BAC0651 | Protein | 3e-90 | 41 |
| merA | YP_113802.1 | mercuric reductase | BAC0224 | Protein | 9e-90 | 41 |
