Gene Information

Name : nrdF (SERP0398)
Accession : YP_187991.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 400714 - 401682 bp
Length : 969 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAGGCGGTAAATTGGAACACCCAAGAAGATATGACTAATATGTTCTGGCGTCAAAATATCTCACAAATGTGGGTGGA
AACAGAATTTAAAGTATCAAAAGATATAGCAAGTTGGAAAACATTAACAGATTCTGAGAAAAATACTTTTAAAAAAGCGC
TTGCAGGTTTAACAGGTTTAGATACACATCAAGCTGATGATGGTATGCCATTAATCATGCTTCATACTACTGATTTAAGA
AAGAAAGCTGTTTATTCATTTATGGCTATGATGGAACAAATCCATGCGAAAAGTTATTCTCATATCTTCACTACATTATT
ACCATCTAGTGAAACCAACTATTTATTGGATACTTGGGTTATTGAAGAGCCACATTTAAAATATAAATCAGATAAAATTG
TAGAAAATTACCACAAACTTTGGGGTAAAGAAGCATCGATTTACGATCAATATATTGCTCGTGTTTCTAGTGTATTCTTA
GAAACATTTCTATTCTATTCTGGCTTCTATTATCCATTATATCTCGCAGGACAAGGAAAAATGACTACGTCAGGTGAAAT
TATACGTAAGATACTTTTAGATGAATCTATACATGGAGTGTTCACAGGTTTAGATGCACAAAGTCTACGTAATGAGTTAT
CTGAAAGTGAGAAACAAAAAGCTGATCAAGAAATGTACAAATTATTAAATGAACTTTATGATAATGAAGTTTCATATACA
CATTTATTATATGATGATATTGGTCTTGCTGAAGATGTATTAAATTATGTTCGATATAATGGAAATAAAGCATTATCGAA
TTTAGGTTTTGAACCATATTTCGAAGAGAGAGAGTTTAACCCTATTATTGAAAATGCACTAGATACATCTACAAAGAACC
ACGATTTCTTCTCTGTTAAAGGTGATGGCTATACATTGGCTTTAAATGTTGAGCCTCTACGTGATGAAGACTTTGTTTTT
GATAATTAA

Protein sequence :
MKAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLTDSEKNTFKKALAGLTGLDTHQADDGMPLIMLHTTDLR
KKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDTWVIEEPHLKYKSDKIVENYHKLWGKEASIYDQYIARVSSVFL
ETFLFYSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQSLRNELSESEKQKADQEMYKLLNELYDNEVSYT
HLLYDDIGLAEDVLNYVRYNGNKALSNLGFEPYFEEREFNPIIENALDTSTKNHDFFSVKGDGYTLALNVEPLRDEDFVF
DN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nrdF YP_189075.1 ribonucleotide-diphosphate reductase subunit beta Not tested ¥ÕSP¥â Protein 5e-83 55