Gene Information

Name : nrdE (SERP0397)
Accession : YP_187990.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 398490 - 400595 bp
Length : 2106 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGAAAACCATGGAAGAAAAGAAATACAATCATATTGAATTAAATAATGAAGTGACCAAGAGAAAAGACAATGGTTTCTT
TGATTTAGAGAAAGATCAAGAAGCATTGAAAGTGTATCTTGAAGAAATCCATGATAAAATGATTTCTTTTGATGATGAAA
TCGAAAGACTTCATTATCTTGTTGATAATAATTTTTATTTTAATGTTTTCGAAAAATATAGCGAAGCAGAATTAATTGAA
ATTACTGAATACGCAAAATCAATTCACTTCCAATTTGCTAGTTATATGTCGGCAAGTAAGTTTTATAAGGATTACGCTTT
AAAAACGAATGATAAAACTAAGTTTCTTGAGGATTATAATCAGCACGTCGCAATCGTTGCACTTTATTTAGCGAATGGTA
ATGTTAAACAAGCAAAACAATTTATTTCTGCAATGGTGGAACAACGTTATCAACCGGCGACACCAACATTCTTGAATGCA
GGTAGAGCAAGACGTGGAGAACTTGTTTCATGTTTCTTATTAGAAGTAGACGATAGCTTAAATTCTATCAATTTCATTGA
TTCAACTGCAAAACAACTTAGTAAAATTGGTGGTGGTGTGGCCATTAATTTATCGAAACTTCGTGCACGTGGAGAAGCAA
TTAAAGGAATTAAAGGTGTAGCTAAAGGTGTTTTACCTGTTGCTAAGGCACTTGAAGGTGGATTTAGTTATGCAGATCAA
TTAGGACAACGTCCTGGCGCTGGGGCAGTGTACTTAAATATTTTCCATTACGATGTTGAAGAGTTTTTAGATACTAAGAA
AGTGAATGCAGATGAAGATTTACGTTTATCTACTATTTCGACTGGTCTTATTGTACCTTCTAAATTCTTTGATTTGGCTA
AAGAGGGTAAAGATTTCTATATGTTTGCACCTCATACAGTTAAACAAGAATACGGTGTGACTTTAGATGATATTGATTTA
GAAAAGTATTACGACGATATGGTTGCAAACCCTAATATCGATAAAAAGAAAAAAGACGCACGTGAAATGTTAAATATGAT
TGCACAAACACAATTACAGTCTGGTTATCCATATCTTATGTTTAAAGATAATGCAAACAAAGTACATGCGAATTCAAATA
TTGGGCAAATTAAAATGAGTAATTTATGTACTGAAATTTTCCAATTACAAGAGACATCAGTAATTAACGACTATGGAATT
GAAGATGAAATTAAAAGAGATATTTCATGTAACTTAGGCTCATTGAATATAGTGAATGTTATGGAATCAGGTAAATTCAG
AGATTCTGTGTTCACAGGTATGGATGCTCTTACAGTTGTAAGTGATGAAGCAAATATTCAAAATGCACCAGGTGTAAAAA
AAGCGAATAGTGAACTACATTCTGTTGGACTAGGAGTAATGAACTTACATGGTTATCTAGCTAAAAATAAAATTGGCTAT
GAATCTGAAGAAGCAAAAGACTTTGCTAATATATTCTTTATGATTATGAACTATTATTCCATCGAACGTTCAATGGAAAT
TGCAAAAGAGCGTGGAGAAAAGTATCAAGACTTTGAGCAATCAGACTATGCAAATGGTAAATATTTTGAATTCTATACAT
CTCAAGAATTTGAACCAAAATTTGAAAAGGTTCGCCAACTTTTTGATGGTATCGATATACCTACTTCAAATGATTGGAAA
GAATTGCAAAATAAAGTAGAACAATATGGACTTTATCACGCTTATAGATTAGCTATTGCTCCGACTCAAAGTATTTCTTA
TGTTCAAAATGCGACAAGTTCTGTTATGCCTATTGTTGACCAAATTGAACGTCGTACGTATGGAAATGCGGAAACATTTT
ATCCAATGCCATTTTTATCACCAGAAACAATGTGGTACTACAAATCAGCATTTAATACTGACCAAATGAAACTTATTGAC
TTAGTAGCTACAATTCAAACTCACGTAGACCAAGGTATTTCAACGATACTTTATGTTAATTCAGAAATTTCAACACGTGA
ACTTTCAAGATTATATGTATATGCACACCATAAAGGCCTTAAATCTTTATACTATACACGTAATAAATTATTAAGTGTGG
AAGAATGTACAAGTTGTGCGATTTAA

Protein sequence :
MKTMEEKKYNHIELNNEVTKRKDNGFFDLEKDQEALKVYLEEIHDKMISFDDEIERLHYLVDNNFYFNVFEKYSEAELIE
ITEYAKSIHFQFASYMSASKFYKDYALKTNDKTKFLEDYNQHVAIVALYLANGNVKQAKQFISAMVEQRYQPATPTFLNA
GRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPVAKALEGGFSYADQ
LGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKQEYGVTLDDIDL
EKYYDDMVANPNIDKKKKDAREMLNMIAQTQLQSGYPYLMFKDNANKVHANSNIGQIKMSNLCTEIFQLQETSVINDYGI
EDEIKRDISCNLGSLNIVNVMESGKFRDSVFTGMDALTVVSDEANIQNAPGVKKANSELHSVGLGVMNLHGYLAKNKIGY
ESEEAKDFANIFFMIMNYYSIERSMEIAKERGEKYQDFEQSDYANGKYFEFYTSQEFEPKFEKVRQLFDGIDIPTSNDWK
ELQNKVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPETMWYYKSAFNTDQMKLID
LVATIQTHVDQGISTILYVNSEISTRELSRLYVYAHHKGLKSLYYTRNKLLSVEECTSCAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 4e-136 43