Gene Information

Name : serS (SERP2545)
Accession : YP_190086.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2603756 - 2605042 bp
Length : 1287 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATTCGTTTATTTAGAAATGAACCTGAGAAAGTGAAGAGCAAAATTGAATTAAGAGGCGACGATCCTAAAGT
TGTCGACCAAGTTTTAGAATTAGATGAACAACGCCGTGAATTAATCAGTAAAACTGAAGAGATGAAGGCGAAAAGAAATA
AAGTGAGCGAAGAAATAGCTCAAAAGAAACGTAATAAAGAAGACGCTGATGACGTCATTGCTGAGATGCGTCATTTAGGT
GATGAAATTAAAGATATCGATAATCAACTTAATGAAGTAGATAATAAAATTAGAGATATCTTAATTCGTATTCCTAACTT
AATTAATGAAGATGTACCTCAAGGTGCTTCTGATGAAGAAAACGTTGAAGTTAAAAAATGGGGTACGCCACGTGATTTTG
AATTTGAACCTAAAGCGCATTGGGATTTAGTTGAAGAATTAAAAATGGCTGACTTTGAACGTGCTGCTAAAGTATCTGGT
GCTCGTTTCGTATACTTAACTAAAGATGGCGCATTACTTGAACGTGCTTTAATGAACTACATGTTGACAAAACATACAAC
GCAACATGGTTATACTGAAATGATGACACCTCAATTAGTGAATGCTGATACGATGTTTGGAACAGGTCAATTACCTAAAT
TTGAAGAAGATTTATTTAAAGTTGAAAAAGAAGGCTTATATACGATTCCAACTGCAGAAGTACCTTTAACAAACTTCTAT
AGAGATGAAATTATTCAACCAGGTGTACTACCTGAATTATTTACAGCTCAAACTGCATGTTTCCGTAGTGAAGCAGGATC
AGCTGGTAGAGATACTAGAGGGTTAATTCGTTTACATCAATTTGATAAAGTTGAAATGGTTCGTATTGTACAACCTGAAG
ATTCTTGGGATGCTTTAGAAGAAATGACACAAAATGCTGAAGCTATTCTTGAAGAATTAGGTTTACCATACCGTCGTGTT
ATCTTATGTACTGGCGATATTGGTTTCAGTGCTAGTAAAACATATGATTTAGAAGTTTGGTTACCAAGTTACAATGATTA
TAAAGAAATCAGTTCTTGCTCTAACTGTACTGATTTCCAAGCACGTCGCGCAAATATCAGATTCAAACGTGATGCTGCTT
CTAAACCAGAATTAGTACACACATTAAATGGTAGTGGTTTAGCTGTAGGTCGTACATTTGCAGCCATCGTTGAAAACTAT
CAAAACGAAGATGGTACATTAACAATTCCTGAAGCATTAGTACCATTTATGGGTGGCAAAACTAAAATTGAAAAACCAAT
CAAATAA

Protein sequence :
MLDIRLFRNEPEKVKSKIELRGDDPKVVDQVLELDEQRRELISKTEEMKAKRNKVSEEIAQKKRNKEDADDVIAEMRHLG
DEIKDIDNQLNEVDNKIRDILIRIPNLINEDVPQGASDEENVEVKKWGTPRDFEFEPKAHWDLVEELKMADFERAAKVSG
ARFVYLTKDGALLERALMNYMLTKHTTQHGYTEMMTPQLVNADTMFGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
RDEIIQPGVLPELFTAQTACFRSEAGSAGRDTRGLIRLHQFDKVEMVRIVQPEDSWDALEEMTQNAEAILEELGLPYRRV
ILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDAASKPELVHTLNGSGLAVGRTFAAIVENY
QNEDGTLTIPEALVPFMGGKTKIEKPIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-120 59