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Name : mecA (SERP2521) Accession : YP_190062.1 Strain : Staphylococcus epidermidis RP62A Genome accession: NC_002976 Putative virulence/resistance : Resistance Product : penicillin-binding protein 2' Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG0768 EC number : 3.4.16.4 Position : 2576656 - 2578662 bp Length : 2007 bp Strand : + Note : identified by similarity to EGAD:16370; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223 DNA sequence : ATGAAAAAGATAAAAATTGTTCCACTTATTTTAATAGTTGTAGTTGTCGGGTTTGGTATATATTTTTATGCTTCAAAAGA TAAAGAAATTAATAATACTATTGATGCAATTGAAGATAAAAATTTCAAACAAGTTTATAAAGATAGCAGTTATATTTCTA AAAGCGATAATGGTGAAGTAGAAATGACTGAACGTCCGATAAAAATATATAATAGTTTAGGCGTTAAAGATATAAACATT CAGGATCGTAAAATAAAAAAAGTATCTAAAAATAAAAAACGAGTAGATGCTCAATATAAAATTAAAACAAACTACGGTAA CATTGATCGCAACGTTCAATTTAATTTTGTTAAAGAAGATGGTATGTGGAAGTTAGATTGGGATCATAGCGTCATTATTC CAGGAATGCAGAAAGACCAAAGCATACATATTGAAAATTTAAAATCAGAACGTGGTAAAATTTTAGACCGAAACAATGTG GAATTGGCCAATACAGGAACAGCATATGAGATAGGCATCGTTCCAAAGAATGTATCTAAAAAAGATTATAAAGCAATCGC TAAAGAACTAAGTATTTCTGAAGACTATATCAAACAACAAATGGATCAAAATTGGGTACAAGATGATACCTTCGTTCCAC TTAAAACCGTTAAAAAAATGGATGAATATTTAAGTGATTTCGCAAAAAAATTTCATCTTACAACTAATGAAACAGAAAGT CGTAACTATCCTCTAGGAAAAGCGACTTCACATCTATTAGGTTATGTTGGTCCCATTAACTCTGAAGAATTAAAACAAAA AGAATATAAAGGCTATAAAGATGATGCAGTTATTGGTAAAAAGGGACTCGAAAAACTTTACGATAAAAAGCTCCAACATG AAGATGGCTATCGTGTCACAATCGTTGACGATAATAGCAATACAATCGCACATACATTAATAGAGAAAAAGAAAAAAGAT GGCAAAGATATTCAACTAACTATTGATGCTAAAGTTCAAAAGAGTATTTATAACAACATGAAAAATGATTATGGCTCAGG TACTGCTATCCACCCTCAAACAGGTGAATTATTAGCACTTGTAAGCACACCTTCATATGACGTCTATCCATTTATGTATG GCATGAGTAACGAAGAATATAATAAATTAACCGAAGATAAAAAAGAACCTCTGCTCAACAAGTTCCAGATTACAACTTCA CCAGGTTCAACTCAAAAAATATTAACAGCAATGATTGGGTTAAATAACAAAACATTAGACGATAAAACAAGTTATAAAAT CGATGGTAAAGGTTGGCAAAAAGATAAATCTTGGGGTGGTTACAACGTTACAAGATATGAAGTGGTAAATGGTAATATCG ACTTAAAACAAGCAATAGAATCATCAGATAACATTTTCTTTGCTAGAGTAGCACTCGAATTAGGCAGTAAGAAATTTGAA AAAGGCATGAAAAAACTAGGTGTTGGTGAAGATATACCAAGTGATTATCCATTTTATAATGCTCAAATTTCAAACAAAAA TTTAGATAATGAAATATTATTAGCTGATTCAGGTTACGGACAAGGTGAAATACTGATTAACCCAGTACAGATCCTTTCAA TCTATAGCGCATTAGAAAATAATGGCAATATTAACGCACCTCACTTATTAAAAGACACGAAAAACAAAGTTTGGAAGAAA AATATTATTTCCAAAGAAAATATCAATCTATTAACTGATGGTATGCAACAAGTCGTAAATAAAACACATAAAGAAGATAT TTATAGATCTTATGCAAACTTAATTGGCAAATCCGGTACTGCAGAACTCAAAATGAAACAAGGAGAAACTGGCAGACAAA TTGGGTGGTTTATATCATATGATAAAGATAATCCAAACATGATGATGGCTATTAATGTTAAAGATGTACAAGATAAAGGA ATGGCTAGCTACAATGCCAAAATCTCAGGTAAAGTGTATGATGAGCTATATGAGAACGGTAATAAAAAATACGATATAGA TGAATAA Protein sequence : MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEVEMTERPIKIYNSLGVKDINI QDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNV ELANTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETES RNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKD GKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTS PGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKK NIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKG MASYNAKISGKVYDELYENGNKKYDIDE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| mecA | NP_370565.1 | penicillin binding protein 2 prime | Not tested | Type-II SCCmec | Protein | 0.0 | 100 |
| mecA | NP_373278.1 | penicillin binding protein 2 prime | Not tested | Type-II SCCmec | Protein | 0.0 | 100 |
| mecA | YP_492752.1 | penicillin-binding protein 2' | Not tested | Type-IV SCCmec | Protein | 0.0 | 100 |
| mecA | BAB72113.1 | penicillin-binding protein 2' | Not tested | Type-IVa SCCmec | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | Not tested | Type-II SCCmec | Protein | 0.0 | 100 |
| mecA | BAB72132.1 | penicillin-binding protein 2' | Not tested | Type-IVb SCCmec | Protein | 0.0 | 100 |
| mecA | YP_039515.1 | penicillin-binding protein 2 prime | Not tested | Type-II SCCmec | Protein | 0.0 | 100 |
| mecA | BAA82220.1 | penicillin binding protein 2' | Not tested | Type-II SCCmec | Protein | 0.0 | 100 |
| SAMSHR1132_00320 | YP_005324556.1 | penicillin-binding protein 2 prime | Not tested | Type-IIIinv SCCmec | Protein | 0.0 | 100 |
| mecA | NP_644846.1 | penicillin binding protein 2 prime | Not tested | Type-IV SCCmec | Protein | 0.0 | 100 |
| mecA | BAD24826.1 | penicillin-binding protein 2' | Not tested | Type-V SCCmec | Protein | 0.0 | 99 |
| unnamed | ACL99850.1 | penicillin binding protein 2a | Not tested | Type-V SCCmec | Protein | 0.0 | 99 |
| mecA | YP_184944.1 | penicillin-binding protein 2' | Not tested | Type-I SCCmec | Protein | 0.0 | 99 |
| SAPIG0042 | YP_005732852.1 | penicillin-binding protein 3 (pbp 3) (pspb20) | Not tested | Type-V SCCmec | Protein | 0.0 | 99 |
| mecA | BAB47623.1 | penicillin-binding protein 2' | Not tested | Type-III SCCmec | Protein | 0.0 | 99 |
| mecA | YP_252006.1 | penicillin binding protein 2 prime | Not tested | SCCmec | Protein | 0.0 | 99 |
| mecA | BAA86650.1 | penicillin-binding protein 2' | Not tested | Type-I SCCmec | Protein | 0.0 | 99 |
| mecA | BAC57478.1 | penicillin-binding protein 2' | Not tested | Type-IIIinv SCCmec | Protein | 0.0 | 99 |
| mecA | BAC67568.1 | penicillin-binding protein 2' | Not tested | Type-IVc SCCmec | Protein | 0.0 | 99 |
| mecA | BAG06200.1 | penicillin-binding protein 2' | Not tested | Type-VII SCCmec | Protein | 0.0 | 99 |
| mecA | YP_005754041.1 | beta-lactam-inducible penicillin-binding protein | Not tested | Type-XI SCCmec | Protein | 0.0 | 65 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_009782.5559258.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_002952.2861157.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_002758.1120001.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_003923.1004781.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_010079.5776902.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_007793.3913904.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_002745.1122812.p0 | Protein | 0.0 | 100 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | AB096217.gene.p01 | Protein | 0.0 | 99 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | NC_002951.3236763.p0 | Protein | 0.0 | 99 |
| mecA | YP_190062.1 | penicillin-binding protein 2' | FR823292.1.gene3.p01 | Protein | 0.0 | 65 |
