Gene Information

Name : spC (SERP2509)
Accession : YP_190051.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Resistance
Product : streptomycin 3''-adenylyltransferase
Function : -
COG functional category : R : General function prediction only
COG ID : COG1708
EC number : 2.7.7.47
Position : 2566052 - 2566834 bp
Length : 783 bp
Strand : +
Note : identified by similarity to EGAD:9921; match to protein family HMM PF01909

DNA sequence : 
ATGAGCAATTTGATTAACGGAAAAATACCAAATCAAGCGATTCAAACATTAAAAATCGTAAAAGATTTATTTGGAAGTTC
AATAGTTGGAGTATATCTATTTGGTTCAGCAGTAAATGGTGGTTTACGCATTAACAGCGATGTAGATGTTCTAGTCGTCG
TGAATCATAGTTTACCTCAATTAACTCGAAAAAAACTAACAGAAAGACTAATGACTATATCAGGAAAGATTGGAAATACG
GATTCTGTTAGACCACTTGAAGTTACGGTTATAAATAGGAGTGAAGTTGTCCCTTGGCAATATCCTCCAAAAAGAGAATT
TATATACGGTGAGTGGCTCAGGGGTGAATTTGAGAATGGACAAATTCAGGAACCAAGCTATGATCCTGATTTGGCTATTG
TTTTAGCACAAGCAAGAAAGAATAGTATTTCTCTATTTGGTCCTGATTCTTCAAGTATACTTGTCTCCGTACCTTTGACA
GATATTCGAAGAGCAATTAAGGATTCTTTGCCAGAACTAATTGAGGGGATAAAAGGTGATGAGCGTAATGTAATTTTAAC
CCTAGCTCGAATGTGGCAAACAGTGACTACTGGTGAAATTACCTCGAAAGATGTCGCTGCAGAATGGGCTATACCTCTTT
TACCTAAAGAGCATGTAACTTTACTGGATATAGCTAGAAAAGGCTATCGGGGAGAGTGTGATGATAAGTGGGAAGGACTA
TATTCAAAGGTGAAAGCACTCGTTAAGTATATGAAAAATTCTATAGAAACTTCTCTCAATTAG

Protein sequence : 
MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRINSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNT
DSVRPLEVTVINRSEVVPWQYPPKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEHVTLLDIARKGYRGECDDKWEGL
YSKVKALVKYMKNSIETSLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spc1 YP_039523.1 streptomycin 3''-adenylyltransferase 1 Not tested Type-II SCCmec Protein 1e-118 100
ant(9) NP_370577.1 O-nucleotidylltransferase Not tested Type-II SCCmec Protein 1e-118 100
ant(9) NP_373289.1 O-nucleotidylltransferase(9) Not tested Type-II SCCmec Protein 1e-118 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase Not tested Type-II SCCmec Protein 1e-118 100
ant(9) BAC57473.1 O-nucleotidyltransferase(9) Not tested Type-IIIinv SCCmec Protein 9e-119 100
spc BAA82204.1 O-nucleotydiltransferase(9) Not tested Type-II SCCmec Protein 9e-119 100

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002745.1124853.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_009782.5559472.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002758.1120013.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002952.2859153.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002745.1122823.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002745.1124325.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002745.1125314.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase GU235985.1.orf1.gene Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_009782.5559439.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002758.1121631.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002952.2859154.p0 Protein 6e-119 100
spC YP_190051.1 streptomycin 3''-adenylyltransferase NC_002745.1123578.p0 Protein 6e-119 100