Gene Information

Name : SERP2435 (SERP2435)
Accession : YP_189980.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Resistance
Product : metallo-beta-lactamase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0491
EC number : -
Position : 2492057 - 2493385 bp
Length : 1329 bp
Strand : +
Note : identified by match to protein family HMM PF00581; match to protein family HMM PF00753

DNA sequence :
ATGTTTTTTAAACAATTTTATGATAAACACTTATCTCAAGCATCTTATTTAATCGGTTGTCAAAAAACTGGAGAAGCCAT
GATTATTGATCCTATTCGTGACTTATCTTCATATATTCGAGTTGCTGATGAAGAAGGTTTAACCATTACTCATGCAGCTG
AAACACATATACATGCAGATTTTGCTTCAGGAATTAGAGATGTTGCTATAAAGTTAAATGCTAGTATTTATGTATCGGGT
GAAAGTGATGACACGTTAGGTTATAAAAATATGCCTAACCAGACTCATTTTGTTCAACATAATGATGATATTTATGTAGG
AAATATAAAATTAAAAGTGCTTCATACACCTGGTCACACGCCAGAAAGTATAAGTTTTTTACTTACTGATGAAGGTGCTG
GAGCACAAGTTCCAATGGGACTATTCAGTGGTGATTTTATTTTTGTAGGAGATATCGGTAGACCTGATTTACTAGAAAAA
GCTGTTAAAGTAGAAGGATCATCTGAAATAGGCGCTAAACAAATGTTTAAATCTATTGAAAGTATTAAAGACTTGCCAAA
CTACATTCAAATTTGGCCTGGCCATGGAGCTGGTAGTCCTTGTGGTAAATCTTTAGGTGCTATTCCAACATCTACTCTTG
GCTATGAAAAACAAACAAACTGGGCTTTTTCTGAAAATAACGAAGCTACCTTTATCGATAAACTAATTTCTGACCAACCT
GCACCACCACATCATTTTGCACAAATGAAAAAAATTAATCAATTCGGTATGAATTTATATCAACCTTATACGGTTTATCC
AGCTACAAATACAAACAGATTAACTTTTGATCTCCGCAGTAAGGAGGCTTATCATGGTGGACATATTGAAGGTACAATCA
ATATTCCATATGATAAAAATTTCATCAATCAAATTGGCTGGTATCTAAACTATGATCAAGAAATTAACTTGATTGGAGAA
TATCACCTTGTTTCAAAAGCAACACACACCTTACAACTCATTGGATATGATGATGTTGCTGGATATCAATTACCTCAATC
TAAGATTCAAACACGTTCCATTCATAGTGAAGATATTACAGGTAACGAATCACATATATTAGATGTACGTAATGATAATG
AATGGAATAATGGCCACTTATCTCAAGCGGTTCATGTACCACACGGCAAACTTTTAGAAACAGATTTACCTTTCAATAGA
AACGATGTTATTTATGTACACTGTCAGTCTGGCATTAGAAGTTCGATAGCTATTGGTATTTTAGAACATAAAGGTTATCA
CAACATTATTAATGTAAATGAAGGTTACAAAGATATACACCTTTCTTAA

Protein sequence :
MFFKQFYDKHLSQASYLIGCQKTGEAMIIDPIRDLSSYIRVADEEGLTITHAAETHIHADFASGIRDVAIKLNASIYVSG
ESDDTLGYKNMPNQTHFVQHNDDIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEK
AVKVEGSSEIGAKQMFKSIESIKDLPNYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFSENNEATFIDKLISDQP
APPHHFAQMKKINQFGMNLYQPYTVYPATNTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYDQEINLIGE
YHLVSKATHTLQLIGYDDVAGYQLPQSKIQTRSIHSEDITGNESHILDVRNDNEWNNGHLSQAVHVPHGKLLETDLPFNR
NDVIYVHCQSGIRSSIAIGILEHKGYHNIINVNEGYKDIHLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 0.0 99
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 0.0 99
unnamed BAB83478.1 - Not tested SCC 12263 Protein 0.0 96
SAV0046 NP_370570.1 hypothetical protein Not tested Type-II SCCmec Protein 1e-123 75
SA0043 NP_373283.1 hypothetical protein Not tested Type-II SCCmec Protein 1e-123 75
unnamed BAC57482.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 1e-123 75