Gene Information

Name : arsB (SERP2430)
Accession : YP_189975.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 2488050 - 2489339 bp
Length : 1290 bp
Strand : +
Note : identified by match to protein family HMM PF02040; match to protein family HMM TIGR00935

DNA sequence :
ATGACAATATTAGCAATCACAATTTTTATATTAACGTTAATTTTTGTTATATGGCAACCTAAAGGTCTAGATATTGGTAT
TACTGCATTAATTGGTGCTGTAGTTGCTATAATCACTGGCGTTGTAAGCTTTTCAGATGTACTAGAAGTTACTGGAATTG
TTTGGAATGCGACCTTAACTTTTGTTGCAGTTATTCTCATTTCACTCATATTAGATGAAATTGGGTTCTTTGAATGGTCT
GCTATACATATGGTGAGAGCATCAAAAGGTAATGGCTTGAAAATGTTTGTTTACATTATGTTGTTAGGCGCTATTGTAGC
AGCTTTCTTTGCGAACGATGGTGCGGCTTTAATACTGACACCTATTGTTTTAGCAATGGTACGTAGTTTAGGATTTGATA
AAAAAGCGGTATTCCCATTTATTATTGCTAGTGGTTTTATTGCAGATACTACGTCTCTTCCATTAATTGTTAGTAATTTA
GTTAATATTGTTTCTGCTGATTACTTTGATATTGGATTTGTTGAGTACTTCAGTAAAATGATTATACCTAATATATTCTC
TTTAATCGCAAGTATTCTTGTCTTATGGCTTTATTTTAGAAAATCTATCCCAAGAAAATTTGATGCAGTAAATATTAGAG
AGCCAAAAGAAGCGATTAAGGACAAAAAGCTTTTTAATATCTCGTGGATTGTACTCACTGTATTGCTAGTTGGTTATTTA
ATAAGTGAGTTTATAAATATTCCAGTATCAATTATTGCTGGTATCATTGCTTTAATATTTGTATTATTAGCACGTAAATC
TAAGGCTGTTCATACGAAACAAGTAATTAAAGGTGCACCATGGAATATTGTTTTATTCTCTATTGGTATGTATCTTGTGG
TATTTGGTCTAAAAAATGTGGGGATTACAACGCTTCTTGGTGATGTACTAACAAATATTTCAAGTTACGGCTTATTTAGT
AGTATCATGGGCATGGGCTTTATATCCGCATTCCTTTCATCCATTATGAACAACATGCCAACTGTTTTAATAGATGCAAT
AGCGATTGGTCAATCTCAAACAACAAGCATACTCAAGGAAGGCATGATTTATGCGAATGTTATCGGATCTGATTTAGGAC
CTAAAATCACACCAATTGGTTCGTTAGCAACACTTCTCTGGTTACATGTGCTTACTCAAAAAGGTGTTAAAATTTCTTGG
GGACAATACTTTAAAATCGGTATTATTATAACGATTCCGGTATTATTTATCACACTGTTAGGGTTATATCTAACACTTAT
TATTTTCTAA

Protein sequence :
MTILAITIFILTLIFVIWQPKGLDIGITALIGAVVAIITGVVSFSDVLEVTGIVWNATLTFVAVILISLILDEIGFFEWS
AIHMVRASKGNGLKMFVYIMLLGAIVAAFFANDGAALILTPIVLAMVRSLGFDKKAVFPFIIASGFIADTTSLPLIVSNL
VNIVSADYFDIGFVEYFSKMIIPNIFSLIASILVLWLYFRKSIPRKFDAVNIREPKEAIKDKKLFNISWIVLTVLLVGYL
ISEFINIPVSIIAGIIALIFVLLARKSKAVHTKQVIKGAPWNIVLFSIGMYLVVFGLKNVGITTLLGDVLTNISSYGLFS
SIMGMGFISAFLSSIMNNMPTVLIDAIAIGQSQTTSILKEGMIYANVIGSDLGPKITPIGSLATLLWLHVLTQKGVKISW
GQYFKIGIIITIPVLFITLLGLYLTLIIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-168 99
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 3e-151 89
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 9e-149 88
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 2e-102 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_189975.1 arsenical pump membrane protein BAC0574 Protein 3e-154 91
arsB YP_189975.1 arsenical pump membrane protein BAC0575 Protein 8e-160 91
arsB YP_189975.1 arsenical pump membrane protein BAC0576 Protein 8e-101 59
arsB YP_189975.1 arsenical pump membrane protein BAC0578 Protein 2e-101 59
arsB YP_189975.1 arsenical pump membrane protein BAC0031 Protein 6e-99 58
arsB YP_189975.1 arsenical pump membrane protein BAC0577 Protein 1e-99 57