Gene Information

Name : aldA-2 (SERP2084)
Accession : YP_189640.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2111487 - 2112980 bp
Length : 1494 bp
Strand : -
Note : identified by similarity to EGAD:15875; match to protein family HMM PF00171

DNA sequence :
ATGACAAATATTAACGTAAGAAATTATATAGATGAAAGTTACGGCTTGTTTATTAACAATGAATTCCAAGCTAGTGATAG
TGGGGAAACATTAACTGTTTCTAATCCAGCTAATGGTGAAGATTTAGCTAAAGTTGCACGCGCTGGTAAAAAAGATGTAG
ATAAAGCTGTTCAAGCAGCTCATGATGCATTTGATAGTTGGAGTAAGATTTCTAAAGAAGAACGTGCAGATTATTTATTA
GAAATTAGTCGACGTATTCATGAGAAAACTGAACATTTAGCGACGGTTGAATCACTGCAAAATGGTAAACCTTATCGTGA
AACATCAACAATTGATGTACCACAAGCAGCCAATCAATTTAAGTATTTTGCTAGTGTTTTAACAACTGACGAAGGTTCAG
TTAATGAAATTGATCAAAATACAATGAGTTTAGTTGTTAATGAACCTGTTGGGGTTGTTGGTGCAGTAGTAGCATGGAAT
TTCCCAATTTTATTAGCTTCATGGAAATTAGGACCGGCTTTAGCAGCAGGTAACACAGTAGTAATTCAACCATCATCATC
TACGCCTTTATCATTAATTGAACTTGCTAAAATTTTCCAAGAAGTTCTTCCTAAAGGAGTAGTTAATGTCTTAACTGGTA
AAGGGTCTGAATCAGGAGACGCTATTTTCCATCATGAAGGTGTAGATAAGTTATCATTTACTGGTTCTACTGACGTGGGT
TACGGTGTAGCACAAGCAGGTGCTGAACGTATCGTTCCTACAACATTAGAACTAGGTGGTAAAAGTGCTAATATTATCTT
TGATGATGCTAATTTAGAGCAAGTGATTGAAGGTGTTCAACTTGGTATATTATTTAACCAAGGTGAAGTATGTAGTGCAG
GTTCAAGATTATTAGTACAATCATCTATTTACGATGAATTGTTGCCAAAATTGAAAGAAGCATTTGAAAATATTAAAGTT
GGCGATCCATTTGATGAAGATACTAAAATGAGTGCGCAAACTGGACCAGAACAATTAGATAAAATTGAAAGTTATATAAA
AATTGCTGAAGAAGATGACAAAGCGAACATCTTAACTGGTGGTCATCGAATCACAGATAACGGCTTAGACAAAGGTTACT
TCTTTGAGCCTACAATTATTGAGATTAACGATAACAAGCATCAACTTGCTCAAGAAGAAATCTTCGGTCCAGTTGTAGTA
GTTGAAAAATTCGATGATGAGCAAGAAGCTATCGAAATTGCAAATGATTCTGAGTATGGTTTAGCTGGAGGTATCTTTAC
TACAGATATTCATCGTGCATTAAATGTAGCTAAAGCTATGAGAACAGGTCGTATTTGGATTAACACTTATAATCAAATTC
CTGCAGGTGCGCCATTCGGAGGATATAAAAAATCAGGTATTGGGCGCGAAGTATATAAAGATGCTATCAAAAACTATCAA
CAAGTTAAAAATATCTTTATTGATACAAGCAACCAAACTAAAGGTTTATATTAA

Protein sequence :
MTNINVRNYIDESYGLFINNEFQASDSGETLTVSNPANGEDLAKVARAGKKDVDKAVQAAHDAFDSWSKISKEERADYLL
EISRRIHEKTEHLATVESLQNGKPYRETSTIDVPQAANQFKYFASVLTTDEGSVNEIDQNTMSLVVNEPVGVVGAVVAWN
FPILLASWKLGPALAAGNTVVIQPSSSTPLSLIELAKIFQEVLPKGVVNVLTGKGSESGDAIFHHEGVDKLSFTGSTDVG
YGVAQAGAERIVPTTLELGGKSANIIFDDANLEQVIEGVQLGILFNQGEVCSAGSRLLVQSSIYDELLPKLKEAFENIKV
GDPFDEDTKMSAQTGPEQLDKIESYIKIAEEDDKANILTGGHRITDNGLDKGYFFEPTIIEINDNKHQLAQEEIFGPVVV
VEKFDDEQEAIEIANDSEYGLAGGIFTTDIHRALNVAKAMRTGRIWINTYNQIPAGAPFGGYKKSGIGREVYKDAIKNYQ
QVKNIFIDTSNQTKGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-99 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-101 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-101 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-101 45
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-101 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA-2 YP_189640.1 aldehyde dehydrogenase VFG0082 Protein 5e-100 45