Gene Information

Name : clpC (SERP0165)
Accession : YP_187761.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 169002 - 171455 bp
Length : 2454 bp
Strand : +
Note : identified by similarity to EGAD:18028; match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861

DNA sequence :
ATGTTATTTGGTAGATTGACAGAGCGTGCACAACGTGTGTTGGCACATGCACAAGAGGAAGCAATTCGTTTGAACCATTC
TAATATTGGAACAGAACATCTTTTGCTTGGTTTAATGAAAGAGCCAGAAGGTATAGCAGCAAAGGTATTAGTAAGTTTTA
ATATTACTGAAGATAAAGTCATCGAAGAAGTTGAAAAACTTATCGGTCACGGTCAAGAGCAAATGGGCACACTACATTAT
ACACCGAGAGCAAAAAAAGTAATTGAACTGTCTATGGATGAAGCTCGAAAGCTACATCATAACTTTGTAGGAACAGAGCA
TATACTATTAGGTTTAATTAGAGAAAATGAAGGTGTTGCAGCACGTGTATTTGCAAACCTAGATTTAAATATTACTAAAG
CACGTGCCCAAGTTGTAAAAGCTTTAGGAAGTCCAGAAATGAGTAATAAAAATGCGCAAGCTAATAAGTCTAATAACACG
CCTACTTTAGATGGATTAGCTAGAGATTTAACTGTTATTGCTAAAGATGGAACGTTAGATCCAGTCGTAGGACGAGATAA
AGAAATTACTCGTGTAATTGAAGTTTTAAGTCGTCGTACTAAAAATAATCCTGTGCTAATTGGTGAACCCGGTGTTGGTA
AAACAGCAATTGCTGAAGGGCTTGCGCAAGCAATTGTTAAAAATGAAGTACCAGAAACTTTAAAAGACAAACGTGTAATG
TCATTAGATATGGGTACAGTCGTAGCTGGCACTAAATATCGTGGTGAATTTGAAGAAAGATTGAAAAAAGTTATGGAGGA
AATCCATCAAGCTGGTAATGTTATTCTATTTATCGATGAACTTCATACTTTAGTTGGCGCTGGTGGCGCAGAAGGAGCAA
TTGATGCATCTAATATTTTAAAACCTGCTTTAGCTCGTGGAGAATTGCAATGTATAGGTGCCACAACATTAGATGAATAT
CGTAAAAATATAGAAAAAGACGCTGCATTAGAACGTCGTTTTCAACCAATTCAAGTGGATGAACCTACAGTTGAAGACAC
GATTGAAATCTTAAAAGGATTACGTGACCGTTATGAGGCTCATCACAGAATTAATATCTCAGATGAAGCTTTAGAAGCGG
CTGCTAAATTGAGTGATCGCTATGTTTCAGATCGTTTCTTGCCAGATAAAGCCATTGACTTAATTGATGAGGCAAGTTCA
AAAGTTAGACTTAAAAGTCATACAACGCCAAGTAATTTAAAAGAGATTGAACAAGAAATTGATAAAGTAAAAAATGAAAA
AGATGCTGCAGTTCATGCTCAAGAATTTGAAAATGCCGCTAATTTAAGAGATAAGCAATCTAAACTTGAAAAGCAATATG
AAGATGCTAAAAATGAATGGAAAAATGCACAAGGTGGTTTAGATACTGCCTTATCTGAAGAAAATATCGCTGAAGTAATA
GCTGGTTGGACAGGTATTCCTTTAACTAAAATTAATGAAACTGAATCAGATCGTTTATTGAATCTTGAAGATACACTTCA
TAAACGTGTCATTGGACAAAACGATGCTGTCAATTCAATTAGTAAAGCTGTTAGAAGAGCTCGTGCTGGTCTTAAAGATC
CAAAACGTCCAATCGGTAGTTTTATTTTCTTAGGACCTACAGGTGTGGGTAAAACTGAATTGGCTCGTGCTTTAGCTGAA
TCTATGTTTGGTGAAGACGATGCAATGATTCGCGTAGATATGAGTGAATTTATGGAGAAACATGCTGTCAGTCGATTAGT
TGGTGCACCTCCAGGATATGTAGGACATGATGACGGCGGTCAATTGACTGAAAAAGTTAGACGTAAACCATACTCTGTGA
TTTTATTTGATGAAATTGAGAAAGCACATCCTGACGTATTTAATATTCTTCTACAAGTTTTAGATGATGGTCATTTAACA
GATACTAAAGGTCGTACTGTGGACTTCCGTAATACTGTGATTATTATGACTTCTAATGTGGGAGCTCAAGAATTACAGGA
CCAACGCTTTGCTGGTTTTGGAGGTGCTTCAGAAGGTAGTGACTACGAAACTGTCAGAAAAACAATGATGAAAGAATTAA
AAAATTCATTCCGACCAGAATTCTTAAACCGTGTTGATGACATTATTGTCTTCCACAAACTTACAAAAGATGAATTAAAA
GAAATTGTTACAATGATGGTAAATAAACTTACTCACCGTCTTTCAGAGCAAAATATTAATATTGTTGTTACTGATAAAGC
GAAAGAAAAAATTGCAGAAGAAGGATATGATCCTGAATATGGTGCTAGACCACTCATTAGAGCAATTCAAAAAACGGTTG
AAGATAATTTAAGCGAATTGATTTTAGATGGAAATAAAATTGAAGGTAAAGAAGTAACAATTGATCATGATGGTAAAGAA
TTTAAGTATGATATTTATGAAATTACAGCTAAAAAAGAAACAACAGAATCATAA

Protein sequence :
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLVSFNITEDKVIEEVEKLIGHGQEQMGTLHY
TPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGSPEMSNKNAQANKSNNT
PTLDGLARDLTVIAKDGTLDPVVGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVKNEVPETLKDKRVM
SLDMGTVVAGTKYRGEFEERLKKVMEEIHQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKNIEKDAALERRFQPIQVDEPTVEDTIEILKGLRDRYEAHHRINISDEALEAAAKLSDRYVSDRFLPDKAIDLIDEASS
KVRLKSHTTPSNLKEIEQEIDKVKNEKDAAVHAQEFENAANLRDKQSKLEKQYEDAKNEWKNAQGGLDTALSEENIAEVI
AGWTGIPLTKINETESDRLLNLEDTLHKRVIGQNDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SMFGEDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLT
DTKGRTVDFRNTVIIMTSNVGAQELQDQRFAGFGGASEGSDYETVRKTMMKELKNSFRPEFLNRVDDIIVFHKLTKDELK
EIVTMMVNKLTHRLSEQNINIVVTDKAKEKIAEEGYDPEYGARPLIRAIQKTVEDNLSELILDGNKIEGKEVTIDHDGKE
FKYDIYEITAKKETTES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_187761.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0079 Protein 0.0 71
clpC YP_187761.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0080 Protein 9e-164 53