Gene Information

Name : nrdF (SERP1510)
Accession : YP_189075.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1572986 - 1574008 bp
Length : 1023 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence : 
ATGACAAGAGAAATTAAAGCAAGAGCAACAAACTGGGACAAAGATAATTCAATAGCGTTAACTTATTGGAAACAAAATGT
AAAACAAATGTGGACTGAAGAGGAATTCAAACCTTCTAAAGATTTAAGTGTTTGGAAGACATTATCTGCGGATGAACAAG
AAACTTATGTTAAAGCACTATCAGGTTTAACAGGTTTAGATACAACACAGGGAACTGAAGGAATGCCTTTATTGGCTTTC
CACTATCCCGAAGAGATTTGGAGAGGAGTATTTGCATTTATGTCTATGATGGAGAATATTCATCATAAGTCGTATTCACA
TATCTTTACTTCACTACTTGAGAGAAAAGATACTCATTACTACTTAAAAGAGTGGGTACCAGCAAATAAATATCTAAACA
AAAAGACAAAATTGATTACAACTAACTATTATAAATTACTTAAACCAAACCCTACTGATCGTGAAATTTATGTAGCAATG
GCTTCATCAATTTTCTTAGAGTCATTCTTATTCTTCTCTGGTTTCTACTATCCATTGTATTTAGCTGGACAAGGTAAAAT
GGTTCACAGTGGAGAAATCATTCGTAAGATTATCTTAGATGAAACTATTCATGGTAGTGGTACAGGATATGCAGCTCAAG
TTATCTTTGATAAATTCAGTAAAGAAGAGCAAGAGGATATTCGTAAAGAGTTGATGGAACTATTTGATCAACTTTACTTC
AATGAGGTTGAATATGCAGCTTCATTATACGATAAGTTAGGTTTAACTGAAGACGTTATTCGTTACATTCAATATAACGG
TAATCGTGCTTTAATGAACTTAGGTTGGGAGACAGTATTTAACCCAGAGCCATTTAACCCTATTGTAGAAAATGGTTTGA
GAACAGATACAACTAACCATGACTTCTTCTCAGTTAAAGGTGACGGTTATACATTAGCATTAAATCAAGTACCTTTACGT
GATAAAGACTTTGATTTCAACAATGTTATTTCATACGAGTTATCTAACAAATTCTTACAATAA

Protein sequence : 
MTREIKARATNWDKDNSIALTYWKQNVKQMWTEEEFKPSKDLSVWKTLSADEQETYVKALSGLTGLDTTQGTEGMPLLAF
HYPEEIWRGVFAFMSMMENIHHKSYSHIFTSLLERKDTHYYLKEWVPANKYLNKKTKLITTNYYKLLKPNPTDREIYVAM
ASSIFLESFLFFSGFYYPLYLAGQGKMVHSGEIIRKIILDETIHGSGTGYAAQVIFDKFSKEEQEDIRKELMELFDQLYF
NEVEYAASLYDKLGLTEDVIRYIQYNGNRALMNLGWETVFNPEPFNPIVENGLRTDTTNHDFFSVKGDGYTLALNQVPLR
DKDFDFNNVISYELSNKFLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nrdF YP_189075.1 ribonucleotide-diphosphate reductase subunit beta Not tested ¥ÕSP¥â Protein 1e-147 100