Gene Information

Name : blaZ-1 (SERP1461)
Accession : YP_189030.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : -
Position : 1526929 - 1527774 bp
Length : 846 bp
Strand : +
Note : identified by similarity to SP:P00807; match to protein family HMM PF00144

DNA sequence :
TTGAAAAAGTTAATACTTTTAATTGCAATTGCTTTAGTTTTAAGTGCATGTAATTCAACCAGTTCACATGCTAAAGAGTT
AAATAATTTAGAAAAGAAATATAATGCTAATATTGGTGTCTATGCATTAGATACTAAAAGTGGTAAGGAAGTAAAATTTA
ATGCCGATAAGAGATTTGCCTATGCTTCAACTTCAAAAGCGATAAATAGTGCTATTTTGTTAGAACAAGTACCTTATAAT
AAGTTAAATAAAAAAGTACATATTAACAAAGATGATATAGTTGCTTATTCTCCTATTTTAGAAAAATATGTAGGAAAAGA
TATCACTTTAAAAGAACTTATTGAGGCTTCAATGAAGTATAGTGATAATACAGCAAACAATAAAATTATAAACGAAATCG
GTGGAATCAAAAAAATTAAAAAACGTTTAAAAAAATTGGGAGATAAAGTAACAAATCCAGTTAGATATGAAATAGAATTA
AATTACTATTCACCAAAGAGCAAAAAAGATACTTCAACGCCTGCTGCTTTCGGCAAGACTTTAAATAAACTTATCGCAAA
TGGAAAATTAAGCAAAAAAAATAAAAATTTCTTACTTGATTTAATGTTAAATAATAAAAACGGAGACACTTTAATTAAAG
ATGGTGTTCCAAAAGACTATAAGGTTGCTGATAAAAGTGGTCAAGCAATAACATATGCTTCTAGAAATGATGTAGCTTTT
GTTTATCCTAAGAACCAATCTGAACCTATTATTTTAGTCATTTTTACGAATAAAGACAATAAAAGTGATAAACCTAATGA
TAAATTGATAAGTGAAACCGCCAAGAATGTAATAAACAAATTTTAA

Protein sequence :
MKKLILLIAIALVLSACNSTSSHAKELNNLEKKYNANIGVYALDTKSGKEVKFNADKRFAYASTSKAINSAILLEQVPYN
KLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGIKKIKKRLKKLGDKVTNPVRYEIEL
NYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQAITYASRNDVAF
VYPKNQSEPIILVIFTNKDNKSDKPNDKLISETAKNVINKF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaZ YP_253679.1 beta-lactamase Not tested ¥ÕSh1 Protein 3e-91 93
blaZ YP_005754040.1 beta-lactamase Not tested Type-XI SCCmec Protein 4e-70 67

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
blaZ-1 YP_189030.1 beta-lactamase NC_010066.5774791.p0 Protein 3e-93 96
blaZ-1 YP_189030.1 beta-lactamase NC_010063.5774822.p0 Protein 6e-92 94
blaZ-1 YP_189030.1 beta-lactamase NC_007931.3978604.p0 Protein 4e-92 94
blaZ-1 YP_189030.1 beta-lactamase NC_005951.2853409.p0 Protein 4e-92 94
blaZ-1 YP_189030.1 beta-lactamase NC_003140.1122765.p0 Protein 4e-92 94
blaZ-1 YP_189030.1 beta-lactamase NC_005011.2598316.p0 Protein 4e-92 94
blaZ-1 YP_189030.1 beta-lactamase M60253.gene.p01 Protein 1e-91 93
blaZ-1 YP_189030.1 beta-lactamase NC_002952.2859819.p0 Protein 1e-91 93
blaZ-1 YP_189030.1 beta-lactamase NC_005127.2610354.p0 Protein 2e-90 93
blaZ-1 YP_189030.1 beta-lactamase NC_005054.2598287.p0 Protein 1e-91 93
blaZ-1 YP_189030.1 beta-lactamase FR823292.1.gene2.p01 Protein 2e-70 67
blaZ-1 YP_189030.1 beta-lactamase HE993884.1.gene8.p01 Protein 2e-61 66
blaZ-1 YP_189030.1 beta-lactamase AF367983.gene.p01 Protein 6e-36 43