Gene Information

Name : leuS (SERP1318)
Accession : YP_188890.1
Strain : Staphylococcus epidermidis RP62A
Genome accession: NC_002976
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1377441 - 1379855 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGAATTATAATCATAAGGAAATTGAAAAAAAGTGGCAGAATTACTGGGAAGAAAATAAGACCTTTAAAACGAATGATAA
TTTAGGACAAAAGAAATTTTATGCATTAGACATGTTTCCTTATCCATCTGGTGCTGGTTTACACGTAGGTCATCCAGAAG
GATATACGGCAACGGATATCATCTCACGATATAAAAGAATGCAAGGTTACAATGTATTACATCCTATGGGGTGGGATGCT
TTTGGTTTGCCGGCAGAACAATATGCTTTAGATACTGGTAATGATCCTCGTGAATTTACACAGAAAAATATTCAAACTTT
CAAAAGACAAATTCAAGAATTAGGATTTAGTTATGATTGGGATAGAGAAGTGAATACTACAGATCCTGAATATTATAAAT
GGACGCAGTGGATATTTATTCAGTTGTATAATAAAGGGTTAGCTTATGTTGATGAAGTTGCTGTCAATTGGTGTCCTGCA
TTAGGTACTGTTTTGTCGAATGAAGAGGTTGTCGATGGGGTATCAGAACGTGGCGGTCATCCTGTTTATCGTAAGCCTAT
GAAACAATGGGTACTCAAAATTACAGAATATGCTGATAGATTACTAGAAGATTTAGATGAGTTAGATTGGCCTGAATCAA
TTAAAGACATGCAACGAAACTGGATTGGACGTTCAGAAGGTGCCAAAGTAACATTTAAAATTGAGCAATCTGACCAAAAT
ATTGAAGTGTTTACGACACGACCAGATACAATCTATGGTACTTCTTTCTTAGTTTTAAGCCCAGAACACCCACTTGTGAA
TGAAATTACGACAAGTGATAAAGAACAAGAAGTCAAATTGTATCAAAATGAAGCATCAAAAAAATCTGATTTAGAACGTA
CGGACTTAGCTAAAGAAAAAACAGGTGTGTTTACTGGAACATTTGCAATTAATCCGCTCTCTGGCGATAAATTACCTATT
TGGATAGCAGATTATGTTTTATCAACTTACGGTACTGGTGCAGTAATGGCTGTGCCTGGACATGATGAGCGAGATCATGA
ATTTGCTACGAAGTTTAATTTACCAATTATCGAAGTTATAGAGGGTGGCGAAGTTCAAAAATATGCATACACAGGTGAAG
GAAAACACATTAATTCTGGAGAATTAGACGGTCTAGAAAATGAAGCGGCAATAAGTAAAGCGATAGAATTGCTTGAATCT
AAAGGTGCTGGTGAGAAAAAAGTCAATTATAAATTACGTGATTGGTTATTTAGTAGGCAACGTTATTGGGGAGAGCCAAT
TCCTATTATACATTGGGAAGATGGATCAATGACTACAGTTCCTGAAGATGAATTGCCTTTACTACTTCCTGAAACAGATG
AAATTAAGCCATCAGGTACCGGTGAATCTCCACTTGCAAATATAGATGCGTTCGTAAACGTTATCGATGAAAAGACAGGT
ATGAAGGGGCGCCGAGAAACCAATACAATGCCTCAATGGGCTGGCAGTTGCTGGTACTATTTACGTTACATTGATCCACA
TAACGAAAAAATGATAGCAGATCCTGAAAAATTAAAGCATTGGCTACCTGTTGATTTATATATTGGAGGCGTGGAACATG
CAGTACTTCACTTATTATATGCAAGATTCTGGCATAAAGTGTTATATGACTTAGGTGTTGTACCAACAAAAGAACCATTC
CAAAAACTATACAATCAGGGAATGATTTTAGGCGAAGGCAATGAAAAAATGAGTAAGTCTAAAGGTAATGTGATTAATCC
AGATGATATTGTTGCATCACATGGTGCTGATACATTACGACTATATGAAATGTTTATGGGACCTTTAGATGCTGCGATCG
CATGGAGTGAAAAAGGTTTAGATGGTTCTAGAAGATTCTTAGATCGTGTTTGGAGACTTATCATTACTGATGAAAATTCA
ATCAATAAAAAAATTGTAGATTCTAACAATCATTCACTTGATAAGGTTTACAATCAAACTGTGAAAAAAGTAACAGAAGA
TTTTGATACACTTAGTTTTAATACTGCAATCAGTCAATTAATGGTGTTTATTAATGAGTGTTATAAAACTAATGAAGTTT
ACAAACCTTATATCGAAGGGTTTGTAAAAATGTTATCGCCTATTGCACCACACATTGGTGAAGAATTATGGGATCGATTA
GGGCATGAAAATACCATTACTTATCAACCATGGCCAACATTTGATGAAAGTTTATTAGTAGATGATGAAGTTGAAATCGT
AGTTCAAGTCAATGGTAAAGTTAGAGCAAAAATCAATATTCCAAAAGATTTATCTAAAGAAGAAATGCAAGACTTAGCCT
TGTCTAATGATAATGTTAAAATGAGTATTGAAGGAAAAGAAGTTAAAAAAGTTATTGCTGTACCTCAAAAGCTAGTTAAT
ATAGTTGCTAAATAA

Protein sequence :
MNYNHKEIEKKWQNYWEENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPA
LGTVLSNEEVVDGVSERGGHPVYRKPMKQWVLKITEYADRLLEDLDELDWPESIKDMQRNWIGRSEGAKVTFKIEQSDQN
IEVFTTRPDTIYGTSFLVLSPEHPLVNEITTSDKEQEVKLYQNEASKKSDLERTDLAKEKTGVFTGTFAINPLSGDKLPI
WIADYVLSTYGTGAVMAVPGHDERDHEFATKFNLPIIEVIEGGEVQKYAYTGEGKHINSGELDGLENEAAISKAIELLES
KGAGEKKVNYKLRDWLFSRQRYWGEPIPIIHWEDGSMTTVPEDELPLLLPETDEIKPSGTGESPLANIDAFVNVIDEKTG
MKGRRETNTMPQWAGSCWYYLRYIDPHNEKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGVVPTKEPF
QKLYNQGMILGEGNEKMSKSKGNVINPDDIVASHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLIITDENS
INKKIVDSNNHSLDKVYNQTVKKVTEDFDTLSFNTAISQLMVFINECYKTNEVYKPYIEGFVKMLSPIAPHIGEELWDRL
GHENTITYQPWPTFDESLLVDDEVEIVVQVNGKVRAKINIPKDLSKEEMQDLALSNDNVKMSIEGKEVKKVIAVPQKLVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 66