Gene Information

Name : smpB (LMOf2365_2421)
Accession : YP_015010.1
Strain : Listeria monocytogenes F2365
Genome accession: NC_002973
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2474666 - 2475130 bp
Length : 465 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCCAAAAGGTGATGGTAAGCTAGTTGCGCAAAATAAAAAAGCGCGCCACGATTACGCAATTGAAGAAACTTTTGAGGC
TGGCATTGTCCTGCAAGGTACTGAAATTAAATCCGTAAGAAACGCACGGGTAAACTTAAAAGATTCCTATGCACGTATCG
ACAAAGGGGAAATTTTCTTACACAATATGCATATTAGTCCTTATGAACAAGGGAACCGCTACAATCATGATCCACTAAGA
ACGCGCAAATTGCTTTTACATAAGAAGCAAATCAGCCGTTTAATTGGAGAAACGAAAGAGTCCGGTTATTCGATTGTTCC
GCTAAAAATGTATATTAAAGATGGCTACGCAAAAGTACTCATCGGTGTAGCTCGAGGTAAAAAGAAATACGATAAACGCC
AAGACTTAAAACAAAAAGAAGCAAAACGTGATATCGAACGCGCTTTTAAAGAGCGCCAACAATAA

Protein sequence :
MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLR
TRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 4e-48 69
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-33 47
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-26 43