Gene Information

Name : thyA (LMOf2365_1904)
Accession : YP_014496.1
Strain : Listeria monocytogenes F2365
Genome accession: NC_002973
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1928892 - 1929836 bp
Length : 945 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATATTTGGATTTAGAAAAGTACGTTTTAGAGAATGGAACACAAAAAGGAGATCGCACTGGAACTGGAACAAT
CAGCACATTTGGTTATCAAATGCGTTTTGATTTACAAGAGGGCTTTCCGATTATGACAACAAAACGGGTACCATTTAAAC
TTGTAGTAAGTGAACTGCTATGGTTTTTACATGGAGATACGAATATTCGCTACCTTTTACAGCATAATAATAATATTTGG
AATGAATGGGCTTTTGAGCGTTTTGTGAAAAGCGATGATTATAAAGGCGAAGATATGACTGACTTTGGACTGCGTGCTGA
GCGTGATTCAGCTTTCAAAGAAGTGTATCAAGCGGAGATGGAGAAGTTTAAAGCTCGGATTTTAGAAGACGAAGCGTTCG
CGAATAAATACGGTGAGCTAGGTAATATTTACGGTAAACAATGGCGCGAATGGAAGACTTCACAAGGAGAAACAATTGAT
CAGTTAGCGGATTTGATTGAAATGATTAAAACGAATCCGAACTCGCGTCGTTTGATTGTGTCTGCTTGGAACCCTGAAGA
TATTCCGAATATGGCTTTACCGCCATGTCATTCGCTATTCCAATTTTATGTAGCGGACGGAAAATTATCATGTCAGCTGT
ATCAACGTAGTGCCGATATTTTCCTTGGTGTACCGTTTAATATTGCAAGCTATGCACTTCTAACACACCTGATTGCACGT
GAAGTAGGGCTGGAAGTTGGCGAGTTTATCCATACTATGGGTGATGCGCATCTTTATAACAATCATATTGAGCAAGTGAA
AGAACAGCTGTCTAGAACACCGCACAAACTTCCAAAATTAGTGCTTTCAGATAAACCAGCAACGATTTTTGATTTTGATG
TAGCGGATATTTCACTGGATGGTTATAATCCAGATCCAGCAATTAAAGCACCAATTTCAGTATAA

Protein sequence :
MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIW
NEWAFERFVKSDDYKGEDMTDFGLRAERDSAFKEVYQAEMEKFKARILEDEAFANKYGELGNIYGKQWREWKTSQGETID
QLADLIEMIKTNPNSRRLIVSAWNPEDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAR
EVGLEVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHKLPKLVLSDKPATIFDFDVADISLDGYNPDPAIKAPISV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-101 65