Gene Information

Name : guaA (LMOf2365_1110)
Accession : YP_013710.1
Strain : Listeria monocytogenes F2365
Genome accession: NC_002973
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1123963 - 1125507 bp
Length : 1545 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAGACTTTACCGAGCAAGAGAAAATTATCGTTCTAGATTTTGGTAGTCAGTACAATCAACTAATTACGCGCCGCAT
TCGTGAGTTCGGTGTGTATAGTGAATTACATCCGCATACTATTACAGTTGAAGAAATGAAAGCACTAAATCCAACGGGGA
TTATTTTTTCAGGAGGACCTAACAGTGTGTATGACGAAGATGCCTTCCGCGCTGACGAAAGAATCTTTGACATGGGAATT
CCGATTTTGGGAATTTGTTACGGCATGCAATTAATGACAACGCACTTCGGTGGCAAAGTAGAACGTGCGAAAGACCGCGA
ATACGGGAAAGCGGACATTCACGTTGAGAAGCCAAACCGTTTATTTGCTGGACTACCAACCGATCAAGTTGTTTGGATGA
GTCACGGCGATTTAGTCGTTGAGGAGCCTGCTGGTTTTGAAGTAACAATTACTAGTAAATCTTGCCCAATTGCAGGTATT
GCGGACGAAGAACGTTCACTTTACGGCGTGCAATTCCACCCAGAAGTACGTCACTCAGTTTACGGCAACGAATTACTGAA
GAATTTTGCATTAAATGTTTGTGGCTGTAAAGGCGACTGGACAATGGAGAACTTTAGTGAAGTAGAAATTGCTAAAATCC
AAGAAATCGTAGGCGACAAAAAAGTCTTGCTTGCCCTTTCTGGCGGCGTAGATTCCTCCGTTGTTGGTGTGTTAATTCAT
AAAGCGATTGGCGACCAACTAACATGTATTTTCGTTGATCATGGCCTTCTTCGTAAAGGGGAAGCTGACCAAGTAATGGC
GACATTACAAGGCGAGTTCAACATGAACATCATCAAAGTAGATGCGAAAAAACGCTTCATGGATAAACTTGCTGGCGTTT
CTGACCCAGAGCAAAAACGTAAAATCATCGGTAACGAATTCATTTACGTATTCGACGATGAAGCTAACAAACTAGACGGC
GTAGAATTCCTAGCTCAAGGAACACTTTATACAGACATCATCGAAAGTGGTACAGCAACTGCCCAAACAATCAAGTCTCA
CCACAATGTAGGCGGCTTACCAGAAGATATGCAATTTAAACTAATCGAACCATTAAATACACTTTTCAAAGATGAAGTTC
GCGCACTAGGAACAGAACTTGGCATGCCTGACGCAATCGTTTGGCGCCAACCATTCCCAGGCCCAGGCTTAGGAATCCGC
GTTCTTGGCGAAATTACGGAAGAGAAATTAGAGATTGTCCGCGATTCTGATTACATCTTGCGTGAAGAAATCAAAAACGC
AGGTCTAGAACGCGAAATCTGGCAATACTTTACTGCTCTTCCAAATATCCGTAGCGTTGGTGTTATGGGTGATGGCAGAA
CGTATGACCATACTGTGGTTGTTCGTGCGGTGACGAGTATTGATGGTATGACAGCCGATTGGGCACGTATTCCGTGGGAT
GTACTGGAGAAAATTTCGGTACGGATTGTGAATGAAGTGGATCACGTGAATCGTGTTGTTTATGATATTACGAGTAAACC
ACCAGCTACGGTTGAGTGGGAGTAA

Protein sequence :
MKDFTEQEKIIVLDFGSQYNQLITRRIREFGVYSELHPHTITVEEMKALNPTGIIFSGGPNSVYDEDAFRADERIFDMGI
PILGICYGMQLMTTHFGGKVERAKDREYGKADIHVEKPNRLFAGLPTDQVVWMSHGDLVVEEPAGFEVTITSKSCPIAGI
ADEERSLYGVQFHPEVRHSVYGNELLKNFALNVCGCKGDWTMENFSEVEIAKIQEIVGDKKVLLALSGGVDSSVVGVLIH
KAIGDQLTCIFVDHGLLRKGEADQVMATLQGEFNMNIIKVDAKKRFMDKLAGVSDPEQKRKIIGNEFIYVFDDEANKLDG
VEFLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTELGMPDAIVWRQPFPGPGLGIR
VLGEITEEKLEIVRDSDYILREEIKNAGLEREIWQYFTALPNIRSVGVMGDGRTYDHTVVVRAVTSIDGMTADWARIPWD
VLEKISVRIVNEVDHVNRVVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 75
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 75
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 75
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-129 53