Gene Information

Name : clpB (CBU_0094)
Accession : NP_819146.1
Strain : Coxiella burnetii RSA 493
Genome accession: NC_002971
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 86265 - 88844 bp
Length : 2580 bp
Strand : +
Note : -

DNA sequence :
ATGCGAATTGATAAATTCACCACAGCATTCCAAACGGCGTTAGCAGACGCGCAATCTTTGGCCGTTGGTCGCGATCATCA
ATTTATAGAACCTGCGCATGTGATGAAAGTATTGCTAGAACAAACGCAAGGCACCGTGGCGCCATTGTTAGAGCAATCAA
AAGTCAATTTATCACGTTTGATTGATGGCGTTAACAAGGCCATCGACAGCTATCCTCAAGTAGAAGGAACCGGCGGAGAA
GTTCATGTGTCCCGCGAATTAAGCAAAATTTTAACGCTGATGGATAAATTTGCTCAGCAAAATAAGGATCAATACATTTC
CTCGGAATGGTTCATTCCCGCCGCGCTCGAAGCCAAAGGTCAATTGCGAGATGTGTTAATAGAGGCCGGTGCTGATAAAA
AAGCCATTGAAAAAAATATCATGAACTTGCGCAAGGGTGAACGAGTGACTGAGCAAAGCGCTGAAGATCAACGGCAGGCA
TTGGCGAAATACACTATTGATCTCACCGAAAAAGCTGAAACTGGAAAACTGGATCCCGTCATTGGACGCGACGAAGAAAT
TCGCCGAACGGTACAAGTGCTACAGCGGCGCACCAAAAATAATCCTGTTCTCATCGGTGAACCGGGCGTGGGTAAAACAG
CGATTGTGGAAGGGTTAGCGCAACGTATCGTCAACGGTGAAGTGCCGGAAGGTTTGAAACAGAAACGATTACTGGCGCTA
GATATGGGCGCATTAATCGCCGGGGCTAAATTTCGAGGAGAATTTGAAGAGCGTTTAAAAGCCGTATTAAAAGATATCGC
TAAGGAGGAAGGTCGGGTTATTTTATTTATCGATGAATTGCACACCATGGTGGGAGCGGGTAAGGCGGAAGGTGCGATGG
ATGCCGGTAATATGTTAAAACCCGCGTTGGCCCGCGGCGAGCTTCATTGTGTGGGTGCAACCACCTTGGATGAATACCGC
AAATACATTGAAAAAGATGCCGCATTAGAACGGCGATTTCAAAAAGTATTGGTTGAGGAGCCTTCAACGGAAGATGCCAT
CGCTATTTTAAGAGGTTTGAAGGAACGTTACGAAGTGCATCATGGCGTTGAAATTACCGATCCTGCGATTATTGCAGCAG
CCACGTTATCTCAACGCTATATTACCGATCGAAATCTTCCCGACAAAGCGATTGATTTAATTGATGAAGCAGCCAGTCAA
ATTCGTATGGAAATGGATTCCAAACCTGTCGAACTGGATCGTTTGGAGCGACGGTTAATTCAGCTAAAAATTGAGCGTGA
AGCTTTAAAAAAAGAAACCGATGAAGCTTCAAAAAAACGGTTGTCCGATCTTGAAACCGAAATTAAAAACGTTGAAAAAG
AATATTCTGATCTCGAAGAAGTGTGGAAAAGTGAAAAAGCTTCATTGCACGGTACTCAACAAATTAAAGAGGAATTGGAA
CAGGCGCGGATTGAATTGGAAGCCGCTGGACGTGCTGGTGATTTGGCGCGAATGTCCGAGCTGCAATATGGAATCATCCC
AGAGCTTGATAAAAAATTAAAAGCGGCTTCCCAGAAAGAAGAGCAATTCCATGATCATAAATTATTACGCAGTCGAGTGA
CCGAAGAAGAAGTCGCCGAAGTCGTCTCGAAATGGACACATATTCCTGTGTCGAAAATGTTGGAGGGCGAGCGCGAGAAA
TTATTGCATATGGAAACTGAATTGCATAAACGCGTCATTGGTCAGGACGAAGCCGTGAACGCCGTGGCAAATGCGATTCG
CCGTTCTCGGGCGGGATTGTCCGACCCTAATCGCCCCGTAGGTTCGTTTTTATTCTTAGGCCCGACAGGGGTGGGGAAAA
CTGAGCTATGCAAAGCATTGGCCGTCTTTTTGTTTGATACGGAAGATGCGATGGTGCGGATTGATATGTCTGAATTTATG
GAAAAGCATTCAGTCGCTCGATTAATCGGCGCACCGCCAGGATACGTGGGTTACGAAGAGGGGGGCTATTTAACAGAGGC
TATCCGCCGTCGGCCTTATTCGGTTATTTTATTAGATGAAATTGAAAAAGCACATAACGACGTATTTAACGTTTTGCTGC
AAGTGTTGGATGACGGTCGATTAACGGACGGTCAGGGTCGAACGGTGGATTTTCGCAATACCGTCATTGTAATGACTTCT
AATCTCGGGTCTGATTTGATTCGGGAATTCTCGGGTGAAAACTACGATAAAATGAAAGACGCCGTGATGGAAGTGGTCGC
ACAACATTTCCGACCTGAGTTTATTAATCGCATTGATGAAGCTGTTGTTTTTCATTCTTTGAAAAAAGAGCAAATTCGCA
ATATTGCGATTATTCAAATCGATCGAATTAAAAAACGCTTGAAAGAAAAAGATTATCAGCTCACGATCAGTGATGACGCG
CTCGATTATTTATCAGAGCTGGGTTACGATCCGGTTTATGGCGCACGACCGCTAAAACGGGTGCTGCAACAACAACTCGA
AAATCCACTCTCCCAGAAAATCTTGGAAGGGAAATTTGTGCCTGGCTCATTAATTAACATTGAGAAAAAGGGCGAACAAT
TAGAATTTAAGGAAGCATGA

Protein sequence :
MRIDKFTTAFQTALADAQSLAVGRDHQFIEPAHVMKVLLEQTQGTVAPLLEQSKVNLSRLIDGVNKAIDSYPQVEGTGGE
VHVSRELSKILTLMDKFAQQNKDQYISSEWFIPAALEAKGQLRDVLIEAGADKKAIEKNIMNLRKGERVTEQSAEDQRQA
LAKYTIDLTEKAETGKLDPVIGRDEEIRRTVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKQKRLLAL
DMGALIAGAKFRGEFEERLKAVLKDIAKEEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVEEPSTEDAIAILRGLKERYEVHHGVEITDPAIIAAATLSQRYITDRNLPDKAIDLIDEAASQ
IRMEMDSKPVELDRLERRLIQLKIEREALKKETDEASKKRLSDLETEIKNVEKEYSDLEEVWKSEKASLHGTQQIKEELE
QARIELEAAGRAGDLARMSELQYGIIPELDKKLKAASQKEEQFHDHKLLRSRVTEEEVAEVVSKWTHIPVSKMLEGEREK
LLHMETELHKRVIGQDEAVNAVANAIRRSRAGLSDPNRPVGSFLFLGPTGVGKTELCKALAVFLFDTEDAMVRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEAIRRRPYSVILLDEIEKAHNDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIVMTS
NLGSDLIREFSGENYDKMKDAVMEVVAQHFRPEFINRIDEAVVFHSLKKEQIRNIAIIQIDRIKKRLKEKDYQLTISDDA
LDYLSELGYDPVYGARPLKRVLQQQLENPLSQKILEGKFVPGSLINIEKKGEQLEFKEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-103 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_819146.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-106 44