Gene Information

Name : CBU_0845 (CBU_0845)
Accession : NP_819865.1
Strain : Coxiella burnetii RSA 493
Genome accession: NC_002971
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 799156 - 800445 bp
Length : 1290 bp
Strand : -
Note : -

DNA sequence :
ATGAACGCCGTCGCAAGGAAAATCGCTGTTATTGGGCTTGGCTATGTGGGTCTTCCCGTTGCTGTTGCTTTTAGCCGTCT
CCAACCGGTCATCGCTTACGACAAAAATTCTGCCCGGATTCGAGCACTTAAACAAGGTTATGATGCCTGCGGCGAAGTTG
ATTCTCAACAGTTACGCACCTGCCAAATTGATTTTACGGACGACCCGGACGATTTAGCAAAAGCTGATTTTTATATCGTT
GCCGTCCCAACGCCCATCGATCAATCAAAACACCCCGATTTATCGCTCCTTCTCAATGCTTCCGAAACTATTGGCCGTTA
TTTAAAACGGGGGGATATCGTTGTTTTTGAATCGACCGTTTACCCGGGCGTCACGGAAGAAGAATGTGCGCCCGTTCTTG
AAAAGGCGTCAGGCCTTAAATATGGCGTTGATTTTACGCTGGGATATTCCCCCGAACGAATTAACCCCAGCGACAAAACG
CATCGGTTTGAAACGATCACCAAAATCGTATCGGGCTCTGATCCTGAAACTTTAGATATTGTCGCCCATGTCTATGGCAG
TGTGATAACCGCCGGCATCTACCGCGCTCCTAGCATTCGCACAGCAGAAGCAGCCAAAGTCATTGAGAATACCCAGCGGG
ATTTAAACATCGCTTTAATGAATGAGCTGGCGATTATTTTTAAGCGGATGGATATCGACACTCAAGAAGTGTTAGCCGCT
GCTGGAACTAAATGGAATTTTTTGCCTTTTAAACCCGGCTTGGTGGGGGGGCACTGCATCGGCGTCGATCCTTATTATCT
CACCTACCAGGCTCAGCGCTATGGCTATAATCCTCAAGTGATCCTTGCCGGTCGCCGTATCAACGATACGATGGGTAAAT
ACATTGCGGAACAAACGATTAAACAAATGATTCACGCGGGTTATACCATTAAAGGCGCTAAGGTGGCTGTTTTGGGTCTC
ACGTTTAAAGAAAATTGCCCCGATCTGCGAAATTCAAAAGTCATCGATATTATCGAGGAATTAAATGATTACGGCATTGA
ATGCGTGGTGCACGATCCTCTTGCCGATCCTGAGGTAGCTAAGCAACTCTATAATATAGATCTTAAATCGTGGGATGAGA
TTCACGATGTGGATTCTTTTGTATTAGCCGTTGCTCATGACCAATTTCACCAATATTCTTTAGAAGACTATCACGCCAAA
TTGGCTCATCATTCGATTATTGTTGATGTCAAAAATGTGTTAAATCCACAAGATTGTAAATCAAATGGCATCACCTTGTG
GAGATTGTAA

Protein sequence :
MNAVARKIAVIGLGYVGLPVAVAFSRLQPVIAYDKNSARIRALKQGYDACGEVDSQQLRTCQIDFTDDPDDLAKADFYIV
AVPTPIDQSKHPDLSLLLNASETIGRYLKRGDIVVFESTVYPGVTEEECAPVLEKASGLKYGVDFTLGYSPERINPSDKT
HRFETITKIVSGSDPETLDIVAHVYGSVITAGIYRAPSIRTAEAAKVIENTQRDLNIALMNELAIIFKRMDIDTQEVLAA
AGTKWNFLPFKPGLVGGHCIGVDPYYLTYQAQRYGYNPQVILAGRRINDTMGKYIAEQTIKQMIHAGYTIKGAKVAVLGL
TFKENCPDLRNSKVIDIIEELNDYGIECVVHDPLADPEVAKQLYNIDLKSWDEIHDVDSFVLAVAHDQFHQYSLEDYHAK
LAHHSIIVDVKNVLNPQDCKSNGITLWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-119 59
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-102 53
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-102 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CBU_0845 NP_819865.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 8e-103 53