Gene Information

Name : hemC (CBU_2074)
Accession : NP_821044.1
Strain : Coxiella burnetii RSA 493
Genome accession: NC_002971
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1976628 - 1977551 bp
Length : 924 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGATCAAAAAACGTAGTATTTTAATTGTCACGCGAAAAAGTCCGCTAGCATTATGGCAGGCTGAATTCGTAAAACAGCA
AATTGAAAATAGTCACCCTCACCTGGCCTGTCAAATCTTGGGGTGCACGACTCAAGGCGATCGTCTTACCACGGAAAAAT
TAGTCGACAGCGGCGGCAAAGACCTTTTTGTTAAAGATTTGCAAAAAGCATTGCTAAATCGCGATGCTGATATTGCCGTA
CATTCTATAAAAGATATGTCGGCTTGCGACGGTCCTGAATTAATGGTCGGTGCTTTTATTCGTCGCGAAGATCCACGCGA
CGTTTTAATAGTAAAGGGTGAATTATCCACTTTACCTCCTCACGCCGTCATCGGAACGTCGAGTCCACGTCGCCAATGTC
AATTGAAAAAATTTCAGCCGGGTTGCAAAATTAAAGAAATTCGAGGCAATGTCGGTACGCGATTAGCTAAACTCGACGCT
GGGCATTACGAGGCTATCGTTCTAGCGGCTGCAGGCTTAAAACGCTTAGGCTTAGAAAATCGAATCCATTATTATTTTGA
TCCTCACGAATTTATACCGGCCATCGGACAAGGCGCCATTGGTGTTGAATGTCGTTCTGATGATCATGAAATGCAAACGC
TCCTAAAATCATTGGACCATCGGGAAACTCGACTTTGTGTGACTGCGGAACGCGCTGTTAATGAAAAACTCGGCGGCGAT
TGCTTTACACCCATTGCAGCGCATGCCATCATTAAAAATGATCAACTTTCGCTGTTTGCGATGCTCGGAAAAATAGACGG
TCGCGTTATAATCCGCGCGACGGAGATTGGAAATTCAGAGGAAGCCAAAAGAATAGGTTTTAAAGTAGCATCGCAATTAT
TAGAACAGGGCGGTGATTCTCTACTGCGTGAGTTAAAACAATAA

Protein sequence : 
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGKDLFVKDLQKALLNRDADIAV
HSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPPHAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDA
GHYEAIVLAAAGLKRLGLENRIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAKRIGFKVASQLLEQGGDSLLRELKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-58 45
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-58 45