Gene Information

Name : murD (CBU_0131)
Accession : NP_819181.1
Strain : Coxiella burnetii RSA 493
Genome accession: NC_002971
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 118036 - 119364 bp
Length : 1329 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAGTAGCGAATCATTAACGGTTATCGTTGGTTTAGGTAAAACGGGATTATCTTGTGCGCAGTTTTTAGCAGCAAAGAA
CCAGCCGTTTGCGGTGATGGACAGTCGTGAAGAACCCCCCGAGTGGGAAAATTTTATCAAAACTTACCCTCGCGTCGAAT
TGATCCGCGGCCAATTTTCGGAAAAATTATTGAACGAAGCGCAAGAGATTATTTTAAGTCCTGGCGTTTCGCTGCAAGAG
CCGTTAATTGCCAAACAAGCAGCGCAAGGCAAATCCATTATTGGCGATATTGAATTATTCGCACGCAATGTGAATAAACC
AATTATTGCTATTACCGGCTCCAATGGCAAAACCACCGTGACGACGGTAGTGGGATTAATGATGAAAGCCGCCGGCCGAA
ACGTTTCAGTTTGCGGTAATATTGGCGAGCCGGTCTTAGAACAAATTACACCTGAGCCGGATTATTACGTACTGGAATTA
TCGAGCTTCCAACTTGAAACGACTTTTTCTTTACGATCTCAAGCGGCAACCATATTAAATATTAGCGAAGACCATATGAA
TCGCTATGCGACTTTACAAGATTATCTCCGAGCTAAACAACGCATTTATACTGATTGTTTTATTCCCATTGTAAACGCGG
ACGAACCAGAAATTTGGCGCCATCTTCCGTTTAATAAAAAACCTTTGTCTTTCGGGTTAAATAATGCTGCTGATTTTTCG
TTGGCAGAACATAATCAAAAAACGTCTATTGCCTATCAGGGTAAGATTTTAATGCCCATCCAAGAATTAAAATTAAACGC
CCGTCATCATCTCCAAAATGCACTTGCTGCATTAGCATTGGGAACAGCAGCTAAAATACCCATAGAAAATATGCTTCATG
TATTACGTGATTTTTCCGGTATCCGCCACCGTTGTCAATGGGTACGCAAGTATAAGGAAATTGATTATTATAATGATTCA
AAAGGCACAAACGTTGGCGCTACCCGCGCTGCCATTGAAAGCTTAGGGCAAGCGGCAAAAGGGCAACTAATCCTTATCGC
TGGCGGACAAGGCAAGGGCGCCGATTTTTCTCCATTAAAAGACGTCGTTAAACGTTACGTTAAACAAGTGATTTTAATCG
GCGAGGATGCTCCGCTGTTAGAAAAAACCTTAAAAGAAATAACCGTTATTAAACACGCTGATTCAATGAACGAAGCCGTC
AAACGATCCACTCAAGCCGCCAAAGCCGGCGATATTGTTTTATTATCCCCCGCTTGCGCGAGTTTTGATATGTTTACCAA
CTACGAACACCGCGGCGATGTTTTTACAGAAACGGTGGAAGCGCTTTAA

Protein sequence :
MSSESLTVIVGLGKTGLSCAQFLAAKNQPFAVMDSREEPPEWENFIKTYPRVELIRGQFSEKLLNEAQEIILSPGVSLQE
PLIAKQAAQGKSIIGDIELFARNVNKPIIAITGSNGKTTVTTVVGLMMKAAGRNVSVCGNIGEPVLEQITPEPDYYVLEL
SSFQLETTFSLRSQAATILNISEDHMNRYATLQDYLRAKQRIYTDCFIPIVNADEPEIWRHLPFNKKPLSFGLNNAADFS
LAEHNQKTSIAYQGKILMPIQELKLNARHHLQNALAALALGTAAKIPIENMLHVLRDFSGIRHRCQWVRKYKEIDYYNDS
KGTNVGATRAAIESLGQAAKGQLILIAGGQGKGADFSPLKDVVKRYVKQVILIGEDAPLLEKTLKEITVIKHADSMNEAV
KRSTQAAKAGDIVLLSPACASFDMFTNYEHRGDVFTETVEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 7e-78 45
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 7e-78 45