Gene Information

Name : serS (CBU_1188)
Accession : NP_820183.1
Strain : Coxiella burnetii RSA 493
Genome accession: NC_002971
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1131109 - 1132380 bp
Length : 1272 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACCCCAAAATATTGCGACAAAATTTAGAGCATGTTGTAGAAAAATTACGCCGCCGCGGTTTTGAAATGGATAG
TGATACTTTCCTTCAATTGGAAAACAAACGCAAAGAGGCTCAATTAGCAATCCAATCTTTCCAAACTAAACGTAACCAAT
TATCAAAAACCATTGGAATGGCGAAATCAAAAGGGGAAAACCCCGAACTCTTAATGGCTGAAGTATCGCAGTTAAACGAT
GAATTAAAGCAGGAAGAAGCTAATTTTGAAACCATTCAGAAGGCTTTCTCTGATTTTCAATTAGCTATCCCTAATTTACC
TCATGATTCAGTGCCCGATGGAAAAAGTGAAAACGATAATCGTGAAATACGACAGTGGGGCGCGCCACCCGGGTTCGATT
TTACGCCAAAAGATCACACGGTTCTTGGCGAACGGGATAACCAATTGGATTTTGAAGCGGCAGCCAAATTGTCGGGCGCG
CGTTTTGTGGTTTTACGGGGATCGTTAGCACGCGCCCATCGTGCTTTGGCGCAATTTATGTTGGATTTACACACCGACCA
ACACGGGTATGAAGAAGTTTATGTGCCGTATTTGGTGCATGAAGAATGCTTATACGGAACAGGACAATTGCCGAAATTTC
GAGAAGAGCAATTTCAAGTTGCCGGCGATCGGAATTTTTTTTTGGTTCCCACGGGTGAAGTGCCCTTGGTTAATTTAGCA
CGAGACGAGATTATCGAAGCGCCAGCGCTTCCTAAAAAATGGGTGGCTCAAACTCCCTGTTTCCGCAGCGAGGCGGGTTC
TTATGGCAAGGATGTACGAGGGATGATTCGCCAGCATCAATTCCAAAAAGTGGAACTTGTTCAACTGGTTCAGCCAGAAA
ATTCTTATCAAGCTTTAGAAGAGATAACCCGTCAGGCTGAAAAAGTATTGCAATTATTGGCGCTTCCCTACCGGGTTGTG
GAGTTATGCGCGGGCGATTTAGGGTTCGCGGCCGCAAAGACTTATGATTTGGAAGTTTGGCTGCCAAGTCAAAATAAATA
CCGAGAGATTTCTTCTTGCAGCAATTGCGAGGATTTTCAAGCCCGACGTATTCAAGCGCGTTGGCGTAATCCCAAAACGG
GAAAGCCTGAACTGCTTCATACTTTAAATGGTTCTGGACTTGCGGTAGGCCGCACATTGGTCGCTGTTATGGAAAACTAT
CAACAAGCCGACGGGCACATTCGTGTGCCCGACGCCTTGAAGTCCTACATGGGTGGAGTGGATTATTTTTAG

Protein sequence :
MLDPKILRQNLEHVVEKLRRRGFEMDSDTFLQLENKRKEAQLAIQSFQTKRNQLSKTIGMAKSKGENPELLMAEVSQLND
ELKQEEANFETIQKAFSDFQLAIPNLPHDSVPDGKSENDNREIRQWGAPPGFDFTPKDHTVLGERDNQLDFEAAAKLSGA
RFVVLRGSLARAHRALAQFMLDLHTDQHGYEEVYVPYLVHEECLYGTGQLPKFREEQFQVAGDRNFFLVPTGEVPLVNLA
RDEIIEAPALPKKWVAQTPCFRSEAGSYGKDVRGMIRQHQFQKVELVQLVQPENSYQALEEITRQAEKVLQLLALPYRVV
ELCAGDLGFAAAKTYDLEVWLPSQNKYREISSCSNCEDFQARRIQARWRNPKTGKPELLHTLNGSGLAVGRTLVAVMENY
QQADGHIRVPDALKSYMGGVDYF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-102 51