Gene Information

Name : TDE0714 (TDE0714)
Accession : NP_971326.1
Strain : Treponema denticola ATCC 35405
Genome accession: NC_002967
Putative virulence/resistance : Virulence
Product : capsular polysaccharide biosynthesis protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 747773 - 749260 bp
Length : 1488 bp
Strand : +
Note : identified by similarity to OMNI:TP0077; match to protein family HMM PF02719

DNA sequence :
ATGAACCGTCCTATTAAACAAAAAACTTCTATATATATAGTAGGCGCAGGTCTGGCCGGAACTATGATTGCACATGAAAT
TTCTGAAAAAAACATATTCGGTAAGGTTGCCGCATTCTTAGACGATGACCCTAAAAAAATCGGAACTAAGATTGACGGGA
TTCCGGTATTCGGGCCTATAAGTGAAACGGTTCATCTGATAAGGATAGATGCAGGGGATGAGGCTCTGATTGCAATTCCC
AGCATGCGCTCCGAGCGTTTGCGTGAAATATATGAGCTTTTAAAATCGGCAGGTTTTTCAAAAATAAAACTTCTGCCCGC
AATTTCGCAAATCATTGACGGTTCAGCTCATTTGGTACAAGCCCGCGAAATAGATCCGCAGGATTTACTTACCCGAACCC
CCGTTACCATTTCTTTAAAAAAGAGTTTGGCTTATCTACGCGGAAAGCGAGTTCTAATTACCGGCGCCGGAGGTTCTATC
GGAAGCGAACTCTGCCGGCAGCTTTTATCGGGCGGTGCCGAACGCCTCTATCTTTTCGGTCATGGAGAAAATTCCATTTA
TCAAATTTATAAAGAACTTAAAATATTGCAAGCAGGCGGTGTCGGCGACAAGGCTACAATTGTTCCGGTTATAGGAGAGT
TAAAAGACCGCGAGTACATGCGCTACATCATTAAGCAATTAAAATGTGATGCGGTTTTTCATACGGCGGCTTATAAACAT
GTTCCTTTGATGGAAGAAAATCCTGTTGCGGTTATCGAAAACAATGTTTTCGGAACAAAGAATCTTTTGGATGCCTGCAT
CGAATTCGGAGTAAAACGATTTGTTTTAATTTCGACGGATAAGGCTGTTGAGCCTGTTTCGGTTTACGGCGTTTCAAAAC
TATTAAGCGAAAAATTGGTATTGCAGGCTGCCGAAACCGTAAAAGAAAAAAAAGATTCAGCCTACATGTTTGTCCGCTTC
GGAAATGTTTTGGGATCGAGGGGATCTATCTTTCCGCTTTTTGTAGAGCAGATACAAAACGGGGGACCCGTAACCGTAAC
CGATAAAAAGATGATCCGCTTTTTTATGACAATTCCGGAAGCTTGTTCATTAGTATTGCAGACAGGCGGTGTTGGAAAAT
CGGGTGAGTCCTATCTTCTCGACATGGGAGAACCTGTAAATATTTATGAGACGGCAAAGCAGTTGATAAGTTACATGGGT
TTTGAACCTGAGAAGGATATTAAGATAGAAATAATCGGCCCCAGAGAAGGCGAGCGTTTGGAAGAGCCTCTTTGGTCATC
AACCGAGTATCTTGAAAAAACGGATTACGAAAAAATCATGCGCTTACGTGATAAAAAAGAATTCGATTCTAAAAACTTAA
ATGAAATTTTAAATACCCTATATCCGTTTTGTTTTTATAGTGAAGAACACAAAGACGATTTCCGCAATAAAGAAAAGATG
CGCAATTTTTTGGAAGAAAATAAATTATTAATTTATAAAAAGGAGTAA

Protein sequence :
MNRPIKQKTSIYIVGAGLAGTMIAHEISEKNIFGKVAAFLDDDPKKIGTKIDGIPVFGPISETVHLIRIDAGDEALIAIP
SMRSERLREIYELLKSAGFSKIKLLPAISQIIDGSAHLVQAREIDPQDLLTRTPVTISLKKSLAYLRGKRVLITGAGGSI
GSELCRQLLSGGAERLYLFGHGENSIYQIYKELKILQAGGVGDKATIVPVIGELKDREYMRYIIKQLKCDAVFHTAAYKH
VPLMEENPVAVIENNVFGTKNLLDACIEFGVKRFVLISTDKAVEPVSVYGVSKLLSEKLVLQAAETVKEKKDSAYMFVRF
GNVLGSRGSIFPLFVEQIQNGGPVTVTDKKMIRFFMTIPEACSLVLQTGGVGKSGESYLLDMGEPVNIYETAKQLISYMG
FEPEKDIKIEIIGPREGERLEEPLWSSTEYLEKTDYEKIMRLRDKKEFDSKNLNEILNTLYPFCFYSEEHKDDFRNKEKM
RNFLEENKLLIYKKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 2e-65 42
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TDE0714 NP_971326.1 capsular polysaccharide biosynthesis protein VFG1300 Protein 2e-67 44