Gene Information

Name : pyk (TDE2535)
Accession : NP_973133.1
Strain : Treponema denticola ATCC 35405
Genome accession: NC_002967
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2561032 - 2562447 bp
Length : 1416 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence : 
ATGAAAAAAACAAAAATAGTATGCACAATAGGGCCCGCTTCCGACTCGGAAAGGGTCTTGGCAGAAATGTTTAAAGCCGG
TTTAAATGTCTGCCGCCTTAATTTTTCGCATGGAAGCCATGAAGAACACAAGGTTAAAATAGATCGAATAAAAAAAATAA
GAGAAGAGTTAAAAATGCCTATTGCACTTTTACTGGATACTAAGGGACCCGAAATCCGTTTGGGCCTTTTTGAAAAGCCT
GTAGAAATTGTACAAGGTCAGGAATTTATAATTACAACCAGAGATGTAATCGGAACAAATCAAATATGCAGCATCTCATA
TAAGAATATTGCCGCCGAAATTAAACCTAAAAGCAGAATCCTTATAAATGACGGATTATTGGAGTTACAGGTTATCGATA
TTTTAAACGATACGGACATAGAATGTGTCGCAGTAAATTCCGGAACCCTAAGCAGCCGAAAAGGTGTAAACATTCCGGGC
TTGAGGGTAAACCTTCCTTACATGAGTGAAAAGGATATCTCCGATATCGAATTCGGAATTGAAAATGATGTGGATTTTAT
TGCCGCCTCCTTTACACAAAGAGCCGACGATATTATCCAAATAAGAAAACTTTTGGAAAAACACAAAAGTACAATCGCCG
TTATAGCAAAAATAGAAAATCAAGAAGGCTTGGACAACATAGATGAAATTTTAGCGGAAGCCGACGGAATAATGGTAGCC
CGGGGAGATATGGGTGTAGAAATAGAGCCCGAAAAAATCCCTCATCTTCAAAAGCAGCTGATAAAAAAAGCAAACCTTGC
AGGAAAGCCGGTTATCACCGCAACTCAGATGCTCGAATCTATGACCCACAACCTGCGTCCCACCAGAGCCGAAGTTACCG
ACGTTGCAAACGCTATTCTCGACGGAACATCAGCTGTAATGCTTTCTGGAGAAACCGCAGCAGGCGAATACCCTGTCGAA
ACCGTGGCCATGATGACCTCAATTGCGAACTCTATAGAAGAAACATTAGATTATGAAAAACTATTTGCTGAAAATGCTTC
TCTTCATGAGACCACAATCACAAATGCAATTGCAAGAGCCACCTGCTCCACTGCCCTAGCCCTCGATGCAAATGCAATCA
TAACGGCATCCGCTTCGGGAATAACGCCCAGAGCTCTTTCAAAATTTAAACCAAGGGTACCGATTATTGCAATAACGGAA
TCGCCTCAGGTTATGAGAAAGATGGCCCTCGACTGGGACGTATATCCGGTTTTAGCCGATCCTATAAAATCGACCGATAA
CATGTTCGATGTGTGTTCGCAAATTGCAAAGGATACAGGCCATGTAAAAAAAGGAGACATAGCAATCCTTACGGCCGGGA
TTCCTATAGGCAAAGCAGGATCTACAAACCTTCTAAAGGTAGAAATAATAGAATAA

Protein sequence : 
MKKTKIVCTIGPASDSERVLAEMFKAGLNVCRLNFSHGSHEEHKVKIDRIKKIREELKMPIALLLDTKGPEIRLGLFEKP
VEIVQGQEFIITTRDVIGTNQICSISYKNIAAEIKPKSRILINDGLLELQVIDILNDTDIECVAVNSGTLSSRKGVNIPG
LRVNLPYMSEKDISDIEFGIENDVDFIAASFTQRADDIIQIRKLLEKHKSTIAVIAKIENQEGLDNIDEILAEADGIMVA
RGDMGVEIEPEKIPHLQKQLIKKANLAGKPVITATQMLESMTHNLRPTRAEVTDVANAILDGTSAVMLSGETAAGEYPVE
TVAMMTSIANSIEETLDYEKLFAENASLHETTITNAIARATCSTALALDANAIITASASGITPRALSKFKPRVPIIAITE
SPQVMRKMALDWDVYPVLADPIKSTDNMFDVCSQIAKDTGHVKKGDIAILTAGIPIGKAGSTNLLKVEIIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-85 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-85 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-85 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-85 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk NP_973133.1 pyruvate kinase VFG0479 Protein 4e-86 44