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Name : leuS (TDE2339) Accession : NP_972938.1 Strain : Treponema denticola ATCC 35405 Genome accession: NC_002967 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 2374985 - 2377561 bp Length : 2577 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGCTTATCCTTTTAGCACGATAGAACCCAAATGGCAAAAATATTGGGAAGAAAACAAAACCTTTAAAACAGTTGAAGA CAAAAATTATCCTAAGGATAAGAGACTCTATATTTTGGATATGTTTCCCTATCCTTCGGGAGACGGGCTCCATGTAGGGC ACCCTGAAGGCTATACAGCAACGGATATTTACAGCCGGTTTTTACGCATGAGCGGATACAATGTACTCCACCCGATGGGC TTTGATTCCTTCGGACTGCCTGCAGAAAACTATGCAATAAAGACAGGAATTCATCCTCTTATCACTACCCGAAAAAATAT GGAAACATTTAGAAAGCAGATAAAGTCCATCGGCTTAAGCTATGACTGGGATAGGGAAATCTCTACAAGCGAAGAATCCT ATTATAAATGGACCCAGTGGATTTTCCTCCAATTATTTAAAAAGGGATTGGCCTACGAAAAAGAAGCCCCCATCAACTGG TGCCCTTCCTGCTTAACAGGCCTTGCCAATGAAGAAGTAAAGGACGGAAAATGCGAAAGATGCGGAGCTCAAATTCAACG CAAAAACTTGAGACAGTGGATTTTAAAGATAACCGAATATGCCGAACGTCTCTTGGAAGATTTAGACGAGCTTGACTGGC CCGAATCCATCAAAATTATGCAAAAAAATTGGATAGGCAAAAGCACCGGGGCTGAGGTTGACTTTGCCCTAGTCGATAAG GACGGAAAAGAAACGGGGCAAAAAATCAAGGTTTATACAACCCGCCCCGACACGATCTTCGGAGCTACCTACATGGTCTT GGCCCCGGAACACGAACTCGTAAAAAGCATAACTACAAGTAACCAAGAAAAAGCCGTTGCCGCTTATATCGAAGAGGCCG CAAAAAAAAGCGACCTCGAAAGAACAGACCTTGCAAAAAACAAGACAGGCGTTTTTACGGGAGCCTATGCAATCAATCCA TTGACGGAACAAAAAATCCCCGTCTGGATTTCGGACTATATTTTAATCTCCTACGGCACGGGAGCAATTATGGCAGTACC CGCCCATGACGAAAGAGACTTTGAGTTTGCTGCCCAATTCAATCTGCCTAAAATCAAGGTTGTAGCCGGTGCGGAAGAAT GGGAAAGCGGAAAAAGAGACTTTTCTGAGGAGCCTAAAGCTTGTACAACCGAGGACGGCTATTCGGTAAACTCAAAACAA TTTGACGGCCTAAAAACGGAAGAAGCAAAAACAAAGATCACGGAACATCTTGAAAACTTAGGCATTGCAAAAAGAGCCGT AAACTACAAGCTCCGTGACTGGATTTTCAGCCGTCAGCGCTATTGGGGTGAGCCCATACCATTGGTACACTGCCCCTCTT GCGGCATAGTTCCCCTGAACGAACATGACCTCCCCCTAACCCTTCCCCAAGTAGAAAGCTATGCTCCAACAGGTACCGGA GAAAGCCCCTTGGCGGCTATTGACTCTTGGGTAAATACAAAATGCCCAAAATGCGGAAAGGAAGCAAAACGGGAAACCAA TACAATGCCTCAGTGGGCAGGTTCTTGCTGGTACTATCTCCGCTTTATAGACCCTCATAACAACGAAGCCTTTGCCGACA AAGAAAAATGCGATTACTGGATGCCTGTCGATCTCTATGTTGGAGGAACCGAACATGCAGTTCTCCATCTATTATATGCA AGGTTTTGGCACAAGGTCTTGTATGATCTGGGTCTGGTCTCTACAAAAGAGCCCTTTACACGGCTTATAAATCAGGGAAT GATAACCTCCTTTGCCTACATGAGAAAAAACAAAAGCCTTGTTCCTGTCGATAAGGTTAAAAAAATATCTGAAACCGAAT TTGAAGACATCGAAACCGGAGAAAAACTTGAACAGGTAATAGCCAAGATGTCCAAGAGCTTAAAGAATGTTATCAATCCT GACGACATCATAAAGGAATATGGGGCAGACACTCTGCGCCTCTACGAAATGTTCTTAGGCCCCTTAGAGGTTTCAAAACC TTGGAACACAAGCGGCATCATGGGCGTATTTAGATTTTTGGAAAAAATCTGGAATCTGTCCGACAGGGAAATATATAAAA CTCCCGTCAACGATACCTCGACCCCTGAAACCAAGACCTTGACAGTTCTTTTAAATAAGACCATAAAAAAGGTAACCGAG GACACAGCCTCTCTTAACTTTAACACTGCTATAAGCCAGATGATGATTTTTATAAACGAGGTTTCAAAGCACAAAAAAAT ACCCCACTATGTTTGGTATAATTTTGTAAAACTTTTAAACCCCTACGCTCCTCACTTGGCTGAAGAGCTTTGGCAAAAGA TGGGTAATGATGAATCGATAGCCTATTCTCACTGGCCGATGTTCGTCGAAAAATTCTGCGTTGACCAAACCTGCACTGTG GTAGTACAGGTAAACGGAAAACTCCGAGGTAAGTTTGAGGCAGAAGCAGGAACCTCTAAAGAGGAACTGGAGCGCCTTGC TCTATCGAATGAGGGAGCCATCCGCAACATTGAAGGCAAGGAAATTAAAAAGATAATTACAGTGCCCGATAAGCTCGTAA ATATTGTAGTACAATAG Protein sequence : MAYPFSTIEPKWQKYWEENKTFKTVEDKNYPKDKRLYILDMFPYPSGDGLHVGHPEGYTATDIYSRFLRMSGYNVLHPMG FDSFGLPAENYAIKTGIHPLITTRKNMETFRKQIKSIGLSYDWDREISTSEESYYKWTQWIFLQLFKKGLAYEKEAPINW CPSCLTGLANEEVKDGKCERCGAQIQRKNLRQWILKITEYAERLLEDLDELDWPESIKIMQKNWIGKSTGAEVDFALVDK DGKETGQKIKVYTTRPDTIFGATYMVLAPEHELVKSITTSNQEKAVAAYIEEAAKKSDLERTDLAKNKTGVFTGAYAINP LTEQKIPVWISDYILISYGTGAIMAVPAHDERDFEFAAQFNLPKIKVVAGAEEWESGKRDFSEEPKACTTEDGYSVNSKQ FDGLKTEEAKTKITEHLENLGIAKRAVNYKLRDWIFSRQRYWGEPIPLVHCPSCGIVPLNEHDLPLTLPQVESYAPTGTG ESPLAAIDSWVNTKCPKCGKEAKRETNTMPQWAGSCWYYLRFIDPHNNEAFADKEKCDYWMPVDLYVGGTEHAVLHLLYA RFWHKVLYDLGLVSTKEPFTRLINQGMITSFAYMRKNKSLVPVDKVKKISETEFEDIETGEKLEQVIAKMSKSLKNVINP DDIIKEYGADTLRLYEMFLGPLEVSKPWNTSGIMGVFRFLEKIWNLSDREIYKTPVNDTSTPETKTLTVLLNKTIKKVTE DTASLNFNTAISQMMIFINEVSKHKKIPHYVWYNFVKLLNPYAPHLAEELWQKMGNDESIAYSHWPMFVEKFCVDQTCTV VVQVNGKLRGKFEAEAGTSKEELERLALSNEGAIRNIEGKEIKKIITVPDKLVNIVVQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 56 |
