Gene Information

Name : clpB (TDE2327)
Accession : NP_972927.1
Strain : Treponema denticola ATCC 35405
Genome accession: NC_002967
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2362138 - 2364717 bp
Length : 2580 bp
Strand : -
Note : identified by similarity to SP:Q9RA63; match to protein family HMM PF00004; match to protein family HMM PF02861

DNA sequence :
ATGAATATAGATAAGTATACAGTTAAGGCATCGGAAGCCGTTCAAGAGGCTTCTTCGCTTGCCCAAAGAGACGACCACAG
TCAGGTTGAAAGTGAACATCTTTTGTATGTTCTTTTAGAACAAGAGGACGGAATTGTTCCGCCTTTAGTAGAAAAAATCG
GAGTAAGTCCCGAAAGTCTTTTGGATGACCTCGATAAAATGCTTGACAGAAAGCCCCGTGTTACGGGACAGTCCGCTCAA
ACTTATATTTCGCCCTTACTTGCAAAGGTTTTTGCAAATGCCGAAGGCTATGCAGATAAATTAAAAGACGAATATGTTTC
TACCGAACATCTTTTGCTTGCCCTAAGCGAATCTAAAGACGAAACGGGAGAACTCTTGCGCTCACGGGGTATCAATCTAA
AAAATCTCCTTTCCGCACTTAAAGAAATCCGCGGAAACAACAGGGTAACGAGCGAAAATCCCGAATCTACATTCAGAAGT
TTGGAAAAATTTTGCCGTGACCTTACACAGCTTGCAAAAAACGAAAAGATAGATCCCGTAATCGGGCGGGATGAAGAAAT
AAGGCGGGTAATGCAGGTTCTTTCCCGTAGAACAAAAAACAATCCCGTTTTGATCGGAGAACCCGGAGTCGGAAAAACAG
CCATAGTCGAAGGCCTTGCAAGGCGTATCGTTTCAGGCGACGTGCCCGACAGCTTAAAGGGAAAAAGACTTTTATCCCTC
GACCTCGGAGCCTTGGTCGCAGGAGCAAAATTCCGCGGCGAATTTGAAGAAAGATTAAAGGCCGTAATTTCCGAAGTGCA
AAAATCCGAAGGCCGAGTCATCCTCTTTATCGACGAGCTTCACACCCTTGTAGGTGCCGGAGCAAGTGAAGGTTCGATGG
ATGCTTCAAACTTATTAAAGCCGGCCCTTGCCCGAGGAGAGCTCAGGGCGATAGGAGCCACTACCCTAAACGAGTACCGA
AAATACATCGAAAAAGATGCAGCCCTTGAACGCCGCTTCCAGCAGGTTTACTGTCCCGAACCTACGGTTGAAGACACAAT
AGCAATCCTGCGCGGCTTACAGGAAAAATATGAAGTTCATCACGGGGTACGCATAAGGGATGAGGCTCTCATAGCGGCAG
CCGTACTTTCCAACCGTTATATCACAAACCGCTTTTTGCCCGACAAGGCGATTGACCTTGTAGATGAGGCTGCAAGCCGT
CTTAAAATGGAAATAGAAAGCCAGCCTGTAGAGCTTGATCAGGTTGAGCGCAAAATTCTTCAGTTGAATATCGAAAAGGT
TTCTATAGGAAAAGAAAACGATACGGCCTCAAAGGAAAGGCTTTTAAAACTTGAAGAAGAGTTGGCGGAGCTTTCTTCAA
AACGGAATGCGATGCAGGCCCAGTGGCAAAACGAAAAAGCCCGCATTAACGAATCCCGCAAATACAAGGAAGAATTGGAA
CAGCTCCGTATCGAAGAAACCAAGTACAGCCGAGAGGGAAACTTAAACAAGGCCGCCGAGCTAAAATACGGAAAAATCCC
CGAACTCGAAAAGAAGATAGCTGCCGTTACTGCCGAGCTTGAAAAAAAAGCCGGTCAGCAGGGACAGCTTTTACGTGAAG
AGGTTTGCGAAGAAGACATAGCCCGAATCGTTTCAATGTGGACAGGTATTCCCGTTGCAAAAATGCTTGCAAGCGAGATG
CAAAAATTTTTACAGCTTGAAAAAGTTTTACAAGCCCGCGTCGTCGGACAAGATGAAGCCGTAAGGGTAGTTTCGGATGC
TATAAGAAGAAACAAGGCAGGCCTTTCCGATATGAACCGTCCCTTGGGAAGTTTTTTATGTATAGGCCCCACCGGTGTCG
GCAAAACCGAATTGGCCAGAACCCTAGCCGATTTTTTGTTCAATGACGAAAAGGCCCTTACCCGAATTGATATGAGCGAG
TACATGGAAAAACATTCCGTGAGCCGCCTGATAGGAGCTCCCCCCGGATATGTGGGTTATGATGAGGGAGGGCAGCTTAC
CGAGGCCGTAAGACGGAGGCCCTACAGCGTAATCCTCTTTGACGAAATCGAAAAAGCGCATCAGGATGTCTTTAACGTCT
TTTTGCAGATTTTGGATGACGGGCGTCTTACCGACGGACAAGGCCGTGTAGTCGATTTTAAGAACACAATTATAATTATG
ACCAGCAACATAGGCTCCGAGTATATATTGACCGCAAAGGATATGGGAAGCATAAAAGAAGAAATTAACCAAATTCTCCG
CGATAATTTTAGGCCCGAATTTTTAAACCGCATCGACGAAATCCTAACCTTTAACAGGCTTGAAAAAGAACATATACGAA
AGATCGTCGATATTCAGCTAAGGTCAGTTGCAGAACGCTTGCAGGCCCGCCGGCTAGGCTTAAAAGTTTCGGATAAGGCG
AAGGATTTTCTTGCAGACATAGGTTACGACCCCATGTTCGGTGCCCGCCCCCTAAAGAGGGCTATACAGGCCGAGCTTGA
AAACAAACTCGCCCGCGAAGTTCTCGAAGGTAAATTCCCCGAAGGAAGCACAATACTGGTTGACAAGGGAGAAAATAGCC
TTATCTTTAAGAAGGGATAA

Protein sequence :
MNIDKYTVKASEAVQEASSLAQRDDHSQVESEHLLYVLLEQEDGIVPPLVEKIGVSPESLLDDLDKMLDRKPRVTGQSAQ
TYISPLLAKVFANAEGYADKLKDEYVSTEHLLLALSESKDETGELLRSRGINLKNLLSALKEIRGNNRVTSENPESTFRS
LEKFCRDLTQLAKNEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSGDVPDSLKGKRLLSL
DLGALVAGAKFRGEFEERLKAVISEVQKSEGRVILFIDELHTLVGAGASEGSMDASNLLKPALARGELRAIGATTLNEYR
KYIEKDAALERRFQQVYCPEPTVEDTIAILRGLQEKYEVHHGVRIRDEALIAAAVLSNRYITNRFLPDKAIDLVDEAASR
LKMEIESQPVELDQVERKILQLNIEKVSIGKENDTASKERLLKLEEELAELSSKRNAMQAQWQNEKARINESRKYKEELE
QLRIEETKYSREGNLNKAAELKYGKIPELEKKIAAVTAELEKKAGQQGQLLREEVCEEDIARIVSMWTGIPVAKMLASEM
QKFLQLEKVLQARVVGQDEAVRVVSDAIRRNKAGLSDMNRPLGSFLCIGPTGVGKTELARTLADFLFNDEKALTRIDMSE
YMEKHSVSRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHQDVFNVFLQILDDGRLTDGQGRVVDFKNTIIIM
TSNIGSEYILTAKDMGSIKEEINQILRDNFRPEFLNRIDEILTFNRLEKEHIRKIVDIQLRSVAERLQARRLGLKVSDKA
KDFLADIGYDPMFGARPLKRAIQAELENKLAREVLEGKFPEGSTILVDKGENSLIFKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-103 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_972927.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2076 Protein 2e-114 42