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Name : megL (TDE2200) Accession : NP_972801.1 Strain : Treponema denticola ATCC 35405 Genome accession: NC_002967 Putative virulence/resistance : Resistance Product : methionine gamma-lyase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 4.4.1.11 Position : 2237340 - 2238545 bp Length : 1206 bp Strand : - Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine DNA sequence : ATGAATAGAAAAGAATTGGAAAAGTTGGGATTTGCTTCAAAACAGATTCACGCAGGAAGCATTAAGAACAAGTACGGTGC TTTAGCTACACCTATTTATCAAACTTCAACATTTGCATTTGATTCGGCAGAACAAGGCGGCAGAAGATTTGCCTTAGAGG AAGAAGGTTATATCTACACCCGTTTAGGTAACCCTACGACTACGGTTGTTGAAGAAAAACTTGCCTGCCTTGAAAACGGG GAAGCCTGTATGTCCGCGAGCTCCGGTATAGGTGCCGTTACCTCATGCATTTGGTCAATTGTAAATGCAGGAGACCATAT CGTTGCCGGAAAGACTCTTTACGGCTGTACATTTGCGTTTTTAAATCACGGTCTGTCACGATTCGGTGTTGATGTAACCT TCGTTGATACCCGTGATCCTGAAAACGTTAAAAAAGCTTTAAAACCGAATACAAAAATCGTTTATTTGGAAACGCCAGCC AACCCGAACATGTATCTTTGCGACATTGCAGCAGTAAGTAAAATTGCCCATGCTCATAATCCCGAATGTAAGGTAATAGT AGATAATACTTATATGACTCCCTATCTTCAAAGGCCTCTTGATTTAGGTGCAGACGTCGTTCTTCATTCTGCAACAAAAT ACCTAAACGGCCATGGAGACGTTATTGCAGGTTTTGTTGTCGGGAAAAAAGAATTCATCGATCAGGTACGCTTTGTAGGT GTTAAGGATATGACAGGTTCTACATTAGGTCCATTTGAAGCTTACTTAATAGGCCGAGGTATGAAGACCCTCGATATCCG AATGGAAAAGCACTGCGCCAATGCTCAAAAAGTTGCAGAGTTCTTGGAAAAACATCCGGCAGTTGAGTCCATCGCCTTCC CCGGTCTTAAATCCTTCCCGCAATATGAGCTTGCAAAAAAACAGATGAAACTTTGCGGAGCTATGATTGCCTTTACCGTT AAGGGCGGATTGGAAGCCGGTAAAACCCTTATAAACTCGGTTAAATTTGCAACCATTGCAGTAAGCTTAGGCGATGCCGA AACCCTTATTCAGCATCCTGCAAGTATGACCCACTCTCCGTATACCCCTGAAGAAAGAGCCGCTTCGGATATTGCCGAAG GTTTGGTACGTCTTTCTGTCGGTCTTGAAGATGCGGAAGATATTATTGCCGATTTAAAACAAGCCTTGGATAAACTTGTT AAATAA Protein sequence : MNRKELEKLGFASKQIHAGSIKNKYGALATPIYQTSTFAFDSAEQGGRRFALEEEGYIYTRLGNPTTTVVEEKLACLENG EACMSASSGIGAVTSCIWSIVNAGDHIVAGKTLYGCTFAFLNHGLSRFGVDVTFVDTRDPENVKKALKPNTKIVYLETPA NPNMYLCDIAAVSKIAHAHNPECKVIVDNTYMTPYLQRPLDLGADVVLHSATKYLNGHGDVIAGFVVGKKEFIDQVRFVG VKDMTGSTLGPFEAYLIGRGMKTLDIRMEKHCANAQKVAEFLEKHPAVESIAFPGLKSFPQYELAKKQMKLCGAMIAFTV KGGLEAGKTLINSVKFATIAVSLGDAETLIQHPASMTHSPYTPEERAASDIAEGLVRLSVGLEDAEDIIADLKQALDKLV K |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 3e-69 | 43 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 6e-70 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| megL | NP_972801.1 | methionine gamma-lyase | BAC0207 | Protein | 8e-108 | 56 |
