Gene Information

Name : TDE2036 (TDE2036)
Accession : NP_972639.1
Strain : Treponema denticola ATCC 35405
Genome accession: NC_002967
Putative virulence/resistance : Virulence
Product : AAA ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2064230 - 2066728 bp
Length : 2499 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861

DNA sequence :
ATGTGTCAAGGTCTTTCACAAGATGCTCATAAGCTGCTTACTCTTTTTGGTCAGCAGGAAGCCAGGCGGGTTAATGCGGA
TCTGTTTCAACCCGAGCATATTTTATCTGCTTTGATCCGCAATAAGGTAGGCAGGGGTTATATAATTCTTCAAAAATTAA
ATATTGATATTCTCAATTTACAGTTATTTATAGAACAGAACACTCCTATCCGTACAGGGGATAGAATCATAGGTGAAATT
CCTCCTTCTCGAAGAATAAAGACTTTGGTCGATATTGCAACAATAGAAGCAAGGACTATGAGGCAAAGTGTTGTCGGTAC
CGAGCATCTTCTTGTAGCCCTCGTCAGAGAAGAAAATTCCATAATATCCGATTTTTTTATGCGGTATAATATCGTGACTG
AAGACATAAGGATGATAATATTAAAAATAACCGATCAGATGGATTCTGTCCGAACCGCTAAAGCAGCCGACGTGTCGAAG
TCAAAATCATCGGCTCTTTCCGAATTTGGACGTAACCTGACCGATATTGTAAGTTCCGGCAGCCTTGACCCAATTATAGG
CCGCGAAAAAGAGATTAGAAGACTTATCCAAATTCTTTCCCGCAGAACAAAAAATAATCCCATCCTTGTAGGAGAGCCCG
GAATAGGAAAGACCTCCATCGTTGAAGGCTTGGCCTTTTCCATAATAAATGAAAACGTGCCTCACGATTTATTGAATAAA
AGTATTGTTTCTTTGGATTTAGGTTCCGTAATTGCAGGAACAAAGTATAGAGGCCAGTTTGAAGAAAGACTGAAGCAAAT
TATAAATGAAATAAAAGAGAATAAAAATATAATTTTGTTTATAGATGAAATTCATACCCTCATAGGTACCGGCGGCTCTC
AGGGAGCGATGGACGCTGCCAATATTTTAAAGCCTGCCCTAGCCAGAGGCGAAATACAATGTATTGGAGCTACTACAGTT
GACGAATACAGAAGATATTTTAAAAACGATTTAGCCCTTGAGCGGCGCTTTCAGTTGATTCAAGTTAAAGAACCGAATCC
TGAAGAGACCTTTGATATACTATGCGGTATAAAACATAAGTATGAAGAACATCACAACGTCATCTATGAACCCCAGACTG
TAACCAAGATAATTGAATATTCAAAACGGTATATCACGGATAGATTTTTTCCTGACAAGGCTATTGATGTATTGGATGAA
GCAGGGGCAATGAAAAAAACTATCCTTGACAAAAAACCCGGCGAACTTTTTGAAATTGAAGACAAGATAAAGGTTTTGAT
GCTTGAAAAAGCCGAGATGGTTGAGATGCAAAATTATGAAAAAGCAGCCTTAATCAGAGACGAAGTCCTTGAGCTAAAAA
ACGATATATATCAAATTAAAAATAAGTGGATGACTTCTTATCAGCATCCTATTTCCTATGTTGATGAAAACGATATAGCA
GAAGTTGTTGCAATGATGACGGATATCCCCGTAAATAAATTGAGCCAAGATGAGGCCGAAAGGATGCTTCATATTGAAGA
TGAATTAAAAAAATCGGTGATAGGGCAAGATGAACCCATATCGATTTTATCCAATTCAATTAGAAGGTCCCGTGCAGGTA
TTTCGTCTCCAGACAGACCCATAGGTTCATTTTTGTTTTTAGGCCCTACCGGTGTCGGAAAAACCCTTCTTGCAAAAACT
CTCGCCGAATTTTTATTCGGCACAAAAGAAGCTTTAATCAGGGTTGATATGAGCGACTATATGGAAAAACATAATGCTGC
AAAACTTATCGGAGCTCCTCCCGGATATGTCGGTTTTGATTCCGGCGGATTTTTAACCGAAAAAATAAGACGAAATCCGT
ATTCCGTTTTGCTTTTGGATGAGGTAGAAAAAGCTCATCCCGATGTCTTTAATATTTTGTTACAAATTTTAGAAGAGGGT
GAGCTTAGAGACAGCAGCGGACGCATCGTCAATTTTAAAAATACGGTTATTATTATGACCAGTAATGCAGGCTCCAAGTC
CATCATAAAAGAAAATCAGTTAGGCTTTAATCTTTCGGGAGATGGTGTAATGGCCTATTCCGAGATAAGAGCAAGCGCTC
TTAACGAAATAAAAAAATTCTTATCACCGGAATTTATAAATAGAATTGATGAGTTGCTTGTTTTTAAGCCCTTGGATAAG
GATGACATCAAACGGATATTAAAGCTTGAGCTTAAAAAATTTGAAGATAGAATTGCAAAGCTGGATTTATATATTGAGCT
TTCAAAAGAAGCCGAAGATTTCTTTGCAGATAAAGGATATGACCCTGCCTACGGTGCACGCCCTATGAGAAGACTTCTTC
AAAATAAAATCGAAGATGTATTGTCCGTTAAAATAATAAGCGGAGAATTTTCAAAGGGTAAGACTGCCCTTGTAGATTTT
TCGGCTTCAGAGAATGATATAATAATCGGCATTAAAGAAAATCCGAATTATGAAGGTGCTTACAGCGCACCAGTTAAATG
TGAGGTCGAATCCAACTGA

Protein sequence :
MCQGLSQDAHKLLTLFGQQEARRVNADLFQPEHILSALIRNKVGRGYIILQKLNIDILNLQLFIEQNTPIRTGDRIIGEI
PPSRRIKTLVDIATIEARTMRQSVVGTEHLLVALVREENSIISDFFMRYNIVTEDIRMIILKITDQMDSVRTAKAADVSK
SKSSALSEFGRNLTDIVSSGSLDPIIGREKEIRRLIQILSRRTKNNPILVGEPGIGKTSIVEGLAFSIINENVPHDLLNK
SIVSLDLGSVIAGTKYRGQFEERLKQIINEIKENKNIILFIDEIHTLIGTGGSQGAMDAANILKPALARGEIQCIGATTV
DEYRRYFKNDLALERRFQLIQVKEPNPEETFDILCGIKHKYEEHHNVIYEPQTVTKIIEYSKRYITDRFFPDKAIDVLDE
AGAMKKTILDKKPGELFEIEDKIKVLMLEKAEMVEMQNYEKAALIRDEVLELKNDIYQIKNKWMTSYQHPISYVDENDIA
EVVAMMTDIPVNKLSQDEAERMLHIEDELKKSVIGQDEPISILSNSIRRSRAGISSPDRPIGSFLFLGPTGVGKTLLAKT
LAEFLFGTKEALIRVDMSDYMEKHNAAKLIGAPPGYVGFDSGGFLTEKIRRNPYSVLLLDEVEKAHPDVFNILLQILEEG
ELRDSSGRIVNFKNTVIIMTSNAGSKSIIKENQLGFNLSGDGVMAYSEIRASALNEIKKFLSPEFINRIDELLVFKPLDK
DDIKRILKLELKKFEDRIAKLDLYIELSKEAEDFFADKGYDPAYGARPMRRLLQNKIEDVLSVKIISGEFSKGKTALVDF
SASENDIIIGIKENPNYEGAYSAPVKCEVESN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-158 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TDE2036 NP_972639.1 AAA ATPase VFG0080 Protein 1e-145 51
TDE2036 NP_972639.1 AAA ATPase VFG0079 Protein 4e-172 46