Gene Information

Name : tkt (TDE1308)
Accession : NP_971914.1
Strain : Treponema denticola ATCC 35405
Genome accession: NC_002967
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1342603 - 1344630 bp
Length : 2028 bp
Strand : +
Note : identified by similarity to SP:P45694; match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232

DNA sequence :
ATGAAAAACGAACTGGAAGCTATTGCTCTTTCAATCAGAAGTCTTTCGATGGACGCAATCGAAAAAGCCAACTCAGGGCA
TCCGGGGCTGCCTTTGGGAGCTGCCGAATTGGGTGCTGCCCTGTATGCTAAAATCTTAAAACACAATCCTAAAAATCCGG
ATTGGAAAGACAGGGACCGCTTTGTGCTTTCTGCAGGCCACGGTTCGATGCTTTTGTATTCAGCCTTACATATTTCAGGC
TACGATGTTTCAATCGAAGATATAAAAAGTTTTAGGCAGCTCGGCTCCAAATGTCCGGGGCATCCCGAATACGGCGACAC
TCCCGGTGTTGAAACTACCACAGGGCCCTTGGGTCAAGGAATTTCTACAGCCGTAGGTATGGCCATTGCCGAAAAAATGC
TTGCCGCCCGCTTTAACACAGCCGAGCATAAAATAGTAGACCATTATACTTATGCCCTTGTAGGGGAGGGCTGTTTGATG
GAGGGCGTTTCCTCCGAAAGCTCCAGTTTGGCAGGCCACTTAAAATTAGGAAAGCTCATTGTTTATTATGATGAAAATAA
GATTACAATTGACGGTTCGACCGACTTAACATTTACCGAAAACATCGAAGAAAGGTACAAGGCCTACGGCTGGCAGGTAT
TGCGCGGTTCGATGTACTCCTTTGAAGATATTGAACGCCTGACTCTTGAAGCTAAAAAAGATGAAAGGCCGACTCTTATT
ATCTTAAAGTCCGTTATAGGTCAGGGGGCTCCGACGGTTGCAGGCAAAAACAAGGCACACGGCGCTCCCTTAGGAAAAGA
CGGCATTGCCGAAGCCAAGAAAAATCTTTTACTCGAAGGAAAAGGCGATTTCTATGTTGCAGAAGAAGCTTATGCTTTCT
TTAAAAAGAGAAATGAAGAGCTGGCTCTTGCTGAAGCCGAATGGAATAAAACCTTTGAAGTCTGGTCAAAAGCCAATCCC
GAAAAAAGAAAAGAATGGGATCTTTCCTTTGCCCAAGGCGGAGCTGATGAAGCCCTTGTAAAATCTGTAAAGCTCCCTGA
GTTCAAAAAAGATGAGAGTCTTGCAACCCGTGCCGCTTCAAAAAAGGCCTTAAACGAGTTTGCAAAAGTCCTTCCCAATC
TTGTCGGAGGTTCTGCCGACTTGGAAGGCCCCAATGCCGTAGGCTTGGACGGAATTTCAGCCTTTTCTCATCAAAATCCT
TCGGGAAGATATATTTATTTCGGTATCAGGGAATTTGCAATGGGGACAATCACAAACGGTATTCAGCTTCACGGAGGTTT
TAGGGCATTTTGTGCGACCTTCTTGGTCTTTGCCGATTATTTACGCCCGGCTCTCCGCCTTGCTGCCCTTATGAAGCTTC
CTTCAATCTATGTATTTACCCATGATTCAATCTTTGTAGGGGAGGACGGCCCCACCCATCAGCCCATAGAACTTTTAGCC
TCATTGCGGGCTATTCCGAATGTTCTTGTTTTACGCCCTGCCGATGCGGAGGAAACAGGGGAAGCATGGAAGCAGGCTCT
CTTACACAAGGACGGCCCCGTATGTTTAATCTTGAGCCGCCAAAATTTACCTGTCTTGGAAAAGAGCGATCTTTTTTGGA
GGGAATCGATTAAAAACGGTGCATACATTGTAAAGGATGTAGAGGCTTCGGCCTCAGGCTGTACGGTAGGCAAGCCGGAT
AGAACTCCTGACGTAACGGTCTTGGCTACGGGCTCCGAGGTAAGTATGGCAGTAAAGGCTGCAAGTCTTGTAAAGGATAA
AAAGGTCAGAGTTGTCTCCGTTATGTCGAAAGAAAGGTTTGAAAACTCGCCTAAGGATTTTAAACATGGAGTTTTGGGCG
GATGTAAAAAGCATATCCGTGTTGTTACCGCCGAGGCTGGAGTCGCCCAAGGCTGGGAAGGCTGGACAGGTTGTAAGTGC
GATAATTTTTCGATTGAGGGTTTCGGCACCTCAGCCCCCGGAGCCAAGGTCGCAGAACACCTAGGCTTTACGTCAGAAAA
CTTGGCAAAGCTGATAGAGAAAAATTAA

Protein sequence :
MKNELEAIALSIRSLSMDAIEKANSGHPGLPLGAAELGAALYAKILKHNPKNPDWKDRDRFVLSAGHGSMLLYSALHISG
YDVSIEDIKSFRQLGSKCPGHPEYGDTPGVETTTGPLGQGISTAVGMAIAEKMLAARFNTAEHKIVDHYTYALVGEGCLM
EGVSSESSSLAGHLKLGKLIVYYDENKITIDGSTDLTFTENIEERYKAYGWQVLRGSMYSFEDIERLTLEAKKDERPTLI
ILKSVIGQGAPTVAGKNKAHGAPLGKDGIAEAKKNLLLEGKGDFYVAEEAYAFFKKRNEELALAEAEWNKTFEVWSKANP
EKRKEWDLSFAQGGADEALVKSVKLPEFKKDESLATRAASKKALNEFAKVLPNLVGGSADLEGPNAVGLDGISAFSHQNP
SGRYIYFGIREFAMGTITNGIQLHGGFRAFCATFLVFADYLRPALRLAALMKLPSIYVFTHDSIFVGEDGPTHQPIELLA
SLRAIPNVLVLRPADAEETGEAWKQALLHKDGPVCLILSRQNLPVLEKSDLFWRESIKNGAYIVKDVEASASGCTVGKPD
RTPDVTVLATGSEVSMAVKAASLVKDKKVRVVSVMSKERFENSPKDFKHGVLGGCKKHIRVVTAEAGVAQGWEGWTGCKC
DNFSIEGFGTSAPGAKVAEHLGFTSENLAKLIEKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-121 46
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-115 44