Gene Information

Name : SAS0386 (SAS0386)
Accession : YP_042511.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG3889
EC number : -
Position : 429842 - 430912 bp
Length : 1071 bp
Strand : +
Note : these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :
ATGAAAATGAGAACAATTACTAAAACCAGTTTAGCACTAGGGCTTTTAACAACAGGCGCAATTACAGTAACGACGCAATC
GGTCAAAGCAGAAAAAATACAATCAACTAAAGTTGACAAAGTACCAACGCTTAAAGCAGAGCGATTAGCAATGATAAACA
TAACAGCAGGTGCAAATTCAGCGACAACACAAGCAGCTAACACAAGACAAGAACGCACGCCTAAACTCGAAAAGGCACCA
AATACTAATGAGGAAAAAACCTCAGCTTCCAAAATAGAAAAAATATCACAACCTAAACAAGAAGAGCAGAAAACGCTTAA
TATATCAGCAACGCCAGCGCCTAAACAAGAACAATCACAAACGACAACCGAATCTACAACGCAGCAAACTAAAATGACAA
CACCTCCATCAACAAACACGCCACAACCAATGCAATCTACTAAATCAGACACACCACAATCTCCAACCATAAAACAAGCA
CAAACAGATATGACTCCTAAATATGAAGATTTAAGAGCGTATTACACGAAACCGAGTTTTGAATTTGAAAAGCAGTTTGG
ATTTTTGCTCAAACCATGGACGACGGTTAGGTTTATGAATGTTATTCCAAATAGGTTCATCTATAAAATAGCTTTAGTTG
GAAAAGATGAGAAAAAATATAAAGATGGACCTTACGATAATATCGATGTATTTATCGTTTTAGAAGACAATAAATATCAA
TTGAAAAAATATTCTGTCGGTGGCATCACGAAGACTAATAGTAAAAAAGTTAATCACAAAGTAGAATTAAGCATTACTAA
AAAAGATAATCAAGGTATGATTTCACGCGATGTTTCAGAATACATGATTACTAAGGAAGAGATTTCCTTGAAAGAGCTTG
ATTTTAAATTGAGAAAACAACTTATTGAAAAACATAATCTTTACGGTAACATGGGTTCAGGAACAATCGTTATTAAAATG
AAAAACGGTGGGAAATATACGTTTGAATTACACAAAAAACTGCAAGAGCATCGTATGGCAGACGTCATAGATGGCACTAA
TATTGATAACATTGAAGTGAATATAAAATAA

Protein sequence :
MKMRTITKTSLALGLLTTGAITVTTQSVKAEKIQSTKVDKVPTLKAERLAMINITAGANSATTQAANTRQERTPKLEKAP
NTNEEKTSASKIEKISQPKQEEQKTLNISATPAPKQEQSQTTTESTTQQTKMTTPPSTNTPQPMQSTKSDTPQSPTIKQA
QTDMTPKYEDLRAYYTKPSFEFEKQFGFLLKPWTTVRFMNVIPNRFIYKIALVGKDEKKYKDGPYDNIDVFIVLEDNKYQ
LKKYSVGGITKTNSKKVNHKVELSITKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHNLYGNMGSGTIVIKM
KNGGKYTFELHKKLQEHRMADVIDGTNIDNIEVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0386 YP_042511.1 superantigen-like protein Virulence vSa¥á Protein 5e-141 100
set18 NP_645201.1 superantigen-like protein Virulence vSa¥á Protein 6e-141 99
SACOL0470 YP_185360.1 superantigen-like protein Virulence vSa¥á Protein 1e-136 98
set3nm YP_001331424.1 superantigen-like protein Virulence vSa¥á Protein 1e-136 98
SAUSA300_0397 YP_493111.1 superantigen-like protein Virulence vSa¥á Protein 1e-136 98
set8 NP_370948.1 superantigen-like protein Virulence vSa¥á Protein 7e-139 97
set8 NP_373634.1 superantigen-like protein Virulence vSa¥á Protein 7e-139 97
SAKOR_00406 YP_008490590.1 Exotoxin Virulence vSa¥á Protein 1e-135 94
SAMSHR1132_03740 YP_005324896.1 exotoxin Virulence vSa¥á Protein 1e-87 64
SAR0425 YP_039877.1 superantigen-like protein Not tested vSa¥á Protein 1e-90 63
SAR0424 YP_039876.1 superantigen-like protein Virulence vSa¥á Protein 4e-84 56